Tim Nice
@tim_nicelab
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Scientist, enteric viruses, host defense
Portland, OR
Joined November 2018
Excited to see this come out in @MucosalImmunol! We set out to find novel regulators of the intestinal antiviral response and discovered a broader role for IRF6 in controlling gut epithelial cell gene expression.
Tim Nice and colleagues @tim_nicelab identify a role for Interferon regulatory factor 6 (IRF6) in intestinal epithelial cell development and immunity: https://t.co/dPOBEzNRMJ
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Interferon lambda represent. Awesome session at #cytokines2024 @CytokineSociety Amazing work presented by @achillebro @Lo_Zanzi @BoulantLab @tim_nicelab @RuneHartmann. Always so great to see what’s happening in the interferon world.
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Don’t miss the symposium “Lambda Interferon” on Oct 3rd @CytokineSociety
https://t.co/EnZQvzsD7M with fantastic talks @achillebro @Megan_Stanifer @RuneHartmann @tim_nicelab @SanghyunLeeLab!! See you there! #InterferonPower
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The Ding Lab at the Washington University in St. Louis ( https://t.co/lr1TRzTcH6) is hiring! We are looking for motivated postdocs and technicians to study rotavirus biology and vaccines using viral reverse genetics, mouse models, and human intestinal organoids. Spread the word!
sdinglab.wustl.edu
A website by WashU Sites
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The lab’s first publication in @CellReports! We show that loss of MEF2A elicits R-loop accumulation and IFN production. R-loop associated molecules, ATR and DDX41, are required for the activation of STING.
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Check out our new paper from the Hinterleitner lab published @ImmunityCP The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells
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Finally, big thanks to our collaborators @VerduLab @DermodyLab @jishnu1729 @MeiselLab @BanaJabri @tim_nicelab @chemgurl @BriglebPam @kishsang and others not on twitter
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AAI is proud to celebrate International Day of Women & Girls in Science. Pictured is Katherine MacNamara who understands that “It is important to me to encourage girls to pursue science as a career” Visit https://t.co/TxmYk7SQL4 for more highlights of women in science.
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I imagine daycare, eldercare, cruise ship staff etc. in outbreak prone settings would be interested in a tx with potential to limit GI viral disease!?!
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Our mouse models showed striking protection of peg-IFNL against norovirus… would be exciting to see if human guts could be similarly protected
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Exciting phase 3 protection of peg-IFNL against respiratory viral disease!
nejm.org
The efficacy of a single dose of pegylated interferon lambda in preventing clinical events among outpatients with acute symptomatic coronavirus disease 2019 (Covid-19) is unclear. We conducted a ra...
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Interferon λ, a new way to cut hospitalizations by 50% after Covid, in a randomized, placebo-controlled trial >2,000 patients age 50+ or high risk @dr_gilmarreis and colleagues https://t.co/njkI3VzbB1
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A commentary on this paper: https://t.co/1hfyLvmTtl
scientificamerican.com
An injection of a type of interferon drastically reduced the risk of severe COVID in a late-stage trial
Interferon λ, a new way to cut hospitalizations by 50% after Covid, in a randomized, placebo-controlled trial >2,000 patients age 50+ or high risk @dr_gilmarreis and colleagues https://t.co/njkI3VzbB1
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Applications to OHSU #PREP (Postbaccalaureate Research Education Program) are now open! OHSU PREP offers a supportive community for exceptional research training and professional development opportunities. Head over to https://t.co/9aw4AqbCsq for more details and to apply!
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Tweet fail. Here is the link https://t.co/z8p9sfPFPc and big thanks to @jakstatman
biorxiv.org
Type I and III Interferons (IFN) constitute the host system’s first line of defense against viral infections. Although the two families use distinct extracellular receptor complexes, an identical...
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Great morning sessions and wonderful lunch discussions at #IFNL2022 #Cytokines2022 Looking forward to more tomorrow!
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I am so grateful for all the support of my lab, my department, my mentors, and colleagues. Especially thankful for the efforts of Lena Li, Bridget Robinson, Mack Peters, @jakevanwinkle, @DaveVariable, Austin Wright, and so many more! I wouldn’t be here without you all
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The University of Michigan is looking for our next virology-focused colleague! Bring your talents to Ann Arbor and join our terrific community! See ad below and spread the word! @BlackInMicro, @AmerSocVirol @STEMInColor_ , @sacnas
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Theres been a lot of negative news lately, but one positive personal development is that my paper on IFN, TNF, and human intestinal epithelial cells with @tim_nicelab, @jakevanwinkle, and many others is officially published! https://t.co/guHLvQbnAb
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