Raghav Sundar
@sundar__raghav
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MD PhD, GI Oncologist in Gastroesophageal Cancer and Peritoneal metastases
Singapore
Joined October 2015
#GastricCancer treatment can make eating difficult and lead to significant weight loss. Dr. @sundar__raghav, of @YaleCancer, highlights the importance of nutrition support and early access to clinical trials to help patients maintain strength. 🎥 https://t.co/5SPqBlXJ20
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Excited for Phase 3 HERIZON-GEA01: zanidatamab + chemo ± tisle improved PFS vs tras + chemo for HER2+ GEA, with significant OS benefit for triplet and OS trend with doublet. Grateful to patients and investigators. Stay tuned for full results @OncoAlert
https://t.co/Ohi299Sf2b
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Sharing our work in the spatial biology of HER2+ gastric cancer @GUTJournal_BMJ. Figuring out and targeting the tumor microenvironment is an exciting time for cancer therapeutics. @FilippoPietran4 @josephjzhao @KoheiShitara
gut.bmj.com
Background Human epidermal growth factor receptor 2 (HER2; ERBB2 ) is overexpressed or amplified in 15–20% of gastric cancers (HER2+ GC). Within individual HER2+ GCs, HER2/ ERBB2 expression is often...
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New Study Highlights Need for Coordinated Approach to Stomach Cancer Screening and Prevention https://t.co/7dyDvwMzVG
@sundar__raghav @YaleCancer
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Collaboration led by @JeeyunM @jitcancer @sitcancer: After 1 cycle chemo, 4/10 (40%) CLDN18.2+ tumors lost expression and 3/29 (10.3%) gained it. CLDN18.2+ TMEs are immune-inflamed yet fibrotic (TGF-β/ECM+) supports serial testing and combo strategies https://t.co/ITXHeMl3Bq
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Tonight on #YaleCancerAnswers, @DrEricWiner speaks with @sundar__raghav, medical oncologist @YaleGICancers. Tune in + learn about breakthroughs, innovative treatments, + Dr. Sundar’s journey from Singapore ➡️ Yale. 🎧Listen live @wnpr 🔁Download @ApplePodcasts 💻Watch @YouTube
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A pair of phase 1 trials evaluating antibody–drug conjugates identify potential strategies to treat advanced gastroesophageal #cancers and highlight the rapid expansion of claudin18.2-targeting drug development in solid tumors. News & Views from @KlempnerSam and @sundar__raghav
nature.com
Nature Medicine - A pair of phase 1 trials evaluating antibody–drug conjugates identify potential strategies to treat advanced gastroesophageal cancers and highlight the rapid expansion of...
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Targeting Claudin18.2 beyond monoclonal antibodies like zolbetixumab is arriving! In this article by @KlempnerSam and myself in @NatureMedicine we discuss two promising Claudin18.2 targeting Antibody-Drug Conjugates.
nature.com
Nature Medicine - A pair of phase 1 trials evaluating antibody–drug conjugates identify potential strategies to treat advanced gastroesophageal cancers and highlight the rapid expansion of...
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Moving immunotherapy into earlier stages of gastroesophageal cancers is a game changer for patients. In this study, we tease out the optimal chemotherapy backbone to combine with immunotherapy. https://t.co/97h7z88uho
@josephjzhao @KlempnerSam
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Examining periop Checkpoint inhibitor benefit in gastro-esophageal cancer... https://t.co/lNe0glc9aD Led by very talented @josephjzhao and Kennedy Ng. @sundar__raghav
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It’s my great honor to write the editorial for the pivotal MATTERHORN study @NEJM @YJanjigianMD @ASCO More global collaboration is needed to further improve outcomes for our patients with gastric/GEJ cancer.@OncoAlert @oncodaily
https://t.co/ZhCzZdCFq4
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Grateful for this award from MASCC. We have been working closely with @RichPaxman to build a device to reduce chemotherapy induced peripheral neuropathy. Awaiting results from the ICE COMPRESS trial. This has been a massive team effort! https://t.co/7W81EdZvsV
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Gastric cancer @TheLancet
https://t.co/wjuz9H4LWn 👏Excellent and comprehensive summary from screening to targeted therapies by @sundar__raghav @LizzySmyth1 @YJanjigianMD @KoheiShitara @HannekevanLaar1
@myESMO
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A tribute to Dr. Agatsuma was a meaningful moment during my DESTINY-Gastric04 presentation at #ASCO25 with @NEJM publication. I deeply respect him and the entire team behind the development of T-DXd. @ASCO @OncoAlert @DaiichiSankyo @DaiichiSankyoUS @AstraZeneca @Oncology_at_AZ
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Cancer patients with B cell malignancies and differential expression of CD24, CDK14 and PLEKHG1 have highest risk of breakthrough infections after SARS-CoV2 vaccination https://t.co/BTmZRfyFDA Thank you @kuanrongchan @sundar__raghav for the collaboration! 😎
nature.com
npj Vaccines - Cancer type and gene signatures associated with breakthrough infections following COVID-19 mRNA vaccination
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Thrilled to share our latest Review on Gastric Cancer in the @TheLancet covering the latest in the treatment and management of this illness @LizzySmyth1 @KoheiShitara @HannekevanLaar1 @MarkarSheraz @YJanjigianMD & Izuma Nakayama.
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String of #AACR25 posts coming up! Proud of the work by @josephjzhao unraveling epigenetic mechanisms of peritoneal metastases in gastroesophageal cancers. @KlempnerSam @JohnnyOngCA
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Published today simultaneously with #AACR25 our work on colorectal cancer peritoneal metastases in Clinical Cancer Research. https://t.co/hJRo0harRw slowly heading toward the goal of treating this difficult disease with novel therapeutics
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Grateful to be given the opportunity to share our work on tumor evolution in gastric cancer and peritoneal metastases at #AACR25 with Dr Sun Young Rha @KlempnerSam @josephjzhao @choong_kun
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