Spirochrome is on Bluesky! Don't forget to give us a follow when you make it there, we'll follow you back!.🦋🦋🦋

RT @spirochrome: 🌑Goodbye bleaching, hello brightness! ☀️. We're thrilled to introduce two new ChloroAlkane (CA) ligands for Halotag labeli….

🌑Goodbye bleaching, hello brightness! ☀️. We're thrilled to introduce two new ChloroAlkane (CA) ligands for Halotag labeling and featuring @ZhixingChen2 fantastic photoresistant BD-dyes!. ✅ Highly photoresistant, no photoblueing.✅ Outstanding brightness.✅ Cell permeable.✅

RT @ZhixingChen2: Check it out at PNAS today. Thank you Alexandre for the collaboration!!. PK Mem probes offer long time-lapse imaging of c….

PKmem probes for gentle membrane imaging are now published in PNAS! Congratulations for these exceptional probes. Available at Spirochrome!.

The first UK Peroxisome Network Meeting in Exeter was a great success!.We're grateful to the organizers for giving us the opportunity to support this great event, especially Dr. Ruth Carmichael for coordinating with us. Triana Amen presented her amazing work on the development

RT @spirochrome: Amazing Kinase activity intergators (Kinprola) posted by Johnsson lab on BioRxiv. If you are looking for the best Halotag….

now published in Nature Chemical Biology:.

Amazing Kinase activity intergators (Kinprola) posted by Johnsson lab on BioRxiv. If you are looking for the best Halotag substrate match for Kinprola: CPY-CA it is available at Spirochrome!.

Our mechanosensitive Flipper-TR™ probes at work in a stunning article by Z. Chen Et al. from @uwanews. The study unveils a PM-ER mechanotransduction mechanism in response to external strain that dose-dependently regulates cellular metabolism.

Dear Yeast friends: Did you know PKmito ORANGE labels very nicely yeast cells mitochondria! . The image appeared in a recent article by @FMCBenning : PKmito ORANGE is a gentle probe with:.✅Fast staining.✅Reduced phototoxicity.✅Robust and specific mito

You can read more about the role of actin in early embryo spindle formation in the recent Science article by @loxstoplox and look at the other 😍 microscopy images and movies.

Let's start the week with this movie kindly shared by @loxstoplox. The movie depicts live imaging of an early mouse embryo labeled with Formin-2-GFP and DNA stained with SPY650-DNA during nuclear envelope breakdown. Note the nuclear dilution of Formin-2-GFP immediately before the

Link to the preprint:

New preprint by @hsi_yin from the Kai Johnsson lab!. A new split Halotag system with higher affinity of the complements + lower background labeling. The system works very well with our SiR-CA & CPY-CA halotag ligands and enables STED imaging or FLIM multiplexing. The short 14

In case you haven't (yet) found a good reason to use our halotag ligands, we strongly suggest reading this great piece from the Johnsson lab!.Congrats to @hsi_yin and all the co-authors.

RT @RetoPaul: The MOSAIC reconfigurable microscope by @Eric_Betzig et al is finally out! . MOSAIC integrates multiple advanced imaging te….

RT @loxstoplox: I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse….

RT @BCM_IntegMicro: Super resolution imaging of mitochondria using PKMito Orange allows for visualization of cristae in real time. https://….

We are thrilled to continue our great collaboration with @ZhixingChen2 and @genvivotech. New products will be launched soon!.

Thank you @AxonsAlex , this movie is mind blowing!. We are immensely proud that, thanks to you, our SPY555-FastAct actin probe is represented at the Nikon Small World in Motion competition!. We'll keep our fingers crossed for the competition 🤞.