Ansu Satpathy
@Satpathology
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immunotherapy, genomics, data, cancer @Stanford @Wing_VC @GladstoneInst @CartographyBio @Immunaitech @joinprox @parkerici
Joined July 2015
I think Brian is talking to Biotech.
"You don't want to be jumping to the hot new thing every time something runs up. The companies that do the best are started typically by people who did when it wasn't cool."
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RT @dhaliwas: Financing news! Excited to share that @AmplifyPartners has led a $30M financing for @tahoe_ai - the latest project in our gr….
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Clone tracing T cell responses in cancer (using TCR-seq methods) has been incredibly valuable for understanding immunotherapy response and opportunities. A holy grail for us has been thinking about to achieve this for innate immune responses in human cancer - with high accuracy.
For innate immune cells, the lack of diverse receptor rearrangements has prevented the study of clonal evolution of the innate immune system in human tissues and tumors. With @satpathology and @caleblareau, I’m delighted to share my PhD work that tackles this challenge:.
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I am a strong believer that depth of data can be just as powerful as scale of data. Deep analysis of small groups of humans, and even individuals, can lead to novel biological insights and principles. Today I am the guinea pig. In my own blood, @CalebLareau finds strong evidence
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RT @aaronmring: T cells do the heavy lifting when it comes to the anti-tumor action of checkpoint immunotherapy. But do antibodies play a r….
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this is such an interesting paper - suggests that the immune system may be a major (and tractable) target for aging intervention. the brain - immune interaction is also interesting, given findings from several groups that have shown replacement of brain microglia by peripheral.
I'm thrilled to share our new study out in @NatureMedicine! We show that a blood test can estimate how aged or youthful one’s organs are and that these organ ages predict future disease and lifespan. Final paper from my PhD in the @wysscoray lab. 🧵1/12.🔗
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RT @euanashley: Atul Butte died yesterday. The world lost a giant. A big bear of a man. With a huge smile. With love for everyone. With ene….
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RT @CancerResearch: 🌟 Meet the 2025 Lloyd J. Old STARs- five extraordinary rising scientific leaders whose work is pushing the boundaries o….
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RT @ScienceKyle: 🚨 New Preprint 🚨 .A continuous landscape of signaling encodes a corresponding landscape of CAR T cell phenotype. How can w….
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RT @AAMortazavi: The general public would think we’re absolutely nuts… derisking is one thing but this is ridiculous $xbi .
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Awesome to have @JSheltzer at Stanford!.
I’m thrilled to share that I’m joining the faculty at the Stanford University School of Medicine. My lab and I will be relocating to Stanford this summer!
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RT @LNuzhna: About a year ago I thought how it must be nice to be building a company working with known tx modality going after known targe….
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RT @HutchInnovation: We are pleased to share our work evaluating some of the latest single-cell platforms, including updated chemistries, i….
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RT @srikosuri: Solving the "replication crisis" is dumb because (1) it's not a crisis, (2) the medicine is worse than the disease. Much of….
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RT @BowTiedBiotech: @Aaron51687924 @AppleHelix If antigen expression is tightly restricted and tumor-specific, like KLK2 versus PSMA, then….
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awesome clone tracing method and story from @AlejoFraticelli and colleagues.
Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in @Nature. This has been an amazing collaboration with the lab of Lars Velten (@larsplus) at @CRGenomica .
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RT @AlejoFraticelli: Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in @Nature. This has been….
nature.com
Nature - The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell...
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I once quit a study section mid-review because a reviewer gave an exceptionally productive physician-scientist trainee (after 15 years of training) a non-fundable K08 score because of small deficiencies in their animal protocol. He said he was being 'fair.' I yelled at him and.
The NIH is broken. Much of $50 billion a year funds bureaucracy, political nonsense, and academic welfare instead of breakthrough science. America needs to slash the red tape, fund bold ideas, and stop rewarding mediocrity if we want to lead the next golden age of science. 🧵
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congratulations to @jacobkimmel @byersblake and team - great to see people driving hard towards innovative medicines!.
We’ve raised a $130 million Series B led by @kleinerperkins alongside new investors @natfriedman/@danielgross , @vkhosla, and @humancapital — joined by existing investors @foundersfund , @_DimensionCap, and @brian_armstrong (yes, the cofounders are doubling down). We also raised.
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