I was on pandero duty last night. So great to see my Puerto Rican community continue to represent at @ABRCMS every year!

Cryo-EM analysis of fibrils from four cardiomyopathic ATTRwt amyloidosis patients reveals identical structures with minimal variability. @saelicesL @RosePedretti9 @lanie1803 @Shumyla44 @FernandezR_MC @Preeti_Singh_V @culkat5 @Singh_Virender @_ahmed_yasmin https://t.co/2f1ngP1vND

2024 has been INSANE so far, and I need to brag about it... So let's start with pubs. My lab has put together 8 papers: 3 accepted on PR journals, 5 on @biorxivpreprint on their way. 5 on structural studies of ATTR fibrils (16 cryoEM structures!), 3 on diagnostic development 🔥

Hi!! This will be a long one but please stay with me! After 3 years doing talks for Puerto Rican undergraduates, high and middle school students talking, about environmental sciences, biology and topics surrounding my research work, I was asked to formalize my efforts. (1/?)

🎉 Congratulations Luis (@orlandolch) on passing your qualifying exam! 📚 Your dedication has paid off, and you're one step closer to earning that PhD! Keep shining bright! 🌟 #PhDLife #AcademicSuccess. @culkat5 why so much enthusiasm?

I’m more than happy to have been a part of this project with the Saelices Lab! ❤️ There’s a lot more to discover about ATTR amyloidosis, so the future looks very exciting!

My lab rocks... I just wanted to share and show off.

Things I wish my academic friends and colleagues knew about Puerto Ricans 🇵🇷: 1) We say “buen provecho” (translates to bon appetite) to not only wish you a good meal, but it is also common curtesy amongst family, friends, and strangers. Talking during meals is not seen as rude.

Our first cryo-EM fibril structure of tau (in collaboration with the Saelices lab!). Structure encodes disease-associated patterns of acetylation. Congrats to Li Li and Binh! @SaelicesL, @UTSWCAND, @UTSWBrain, @UTSWNews https://t.co/NrzDHhSl3d

New @biorxivpreprint explores post-translational modifications, such as O-GlcNAc modification, of #Parkinsons-associated α-Synuclein; Heat shock proteins interactions with O-GlcNAc fibrils inhibit their seeding activity; From @aaronbalana @MattRPratt et al https://t.co/zq8O16z1Vp

One more outing and so much fun! Thanks @RosePedretti9 for organizing!

He finshed his confocal session for today https://t.co/JKvGIrk2Er

The U.S. launched a racist eugenics program in Puerto Rico in the 1930s — sterilizing about one third of Puerto Rican women by 1976, many forced or coerced. It was just one chapter of U.S. colonial eugenics programs and medical experiments targeting women of color. 🧵(1/8)

We are going after you. Watch your back. Lab outing #6??? Always a blast! Thanks a lot @RosePedretti9 for organizing! @FernandezR_MC @_ahmed_yasmin @gvald2 @orlandolch

#academia has its ups and downs, but my lab sure knows how to put a smile on my face. I came back from a conference to this #wholesome door

New🔥 #DataScience #Bioinformatics resource: 850,000‼️ #scRNAseq cells from 226 samples across 10 cancer types draw a map of the tumor microenvironment, in particular fibroblasts. Let’s see👇what are the main contributions of this work & what this means for #cancer #Genomics🧵

🧐🤓Programa RAMP-UP, único en 🇵🇷, proveerá investigación post bachillerato a estudiantes de UPR Los estudiantes obtendrán experiencia investigativa, mentoría, ayuda hacia sus estudios graduados y un estipendio. Todo lo encuentras aquí ⬇️ https://t.co/IcIbxBK7dr

(mensaje para estudiantes de escuela superior y bachillerato) 🇵🇷 Si quieres ser científico y tienes dudas sobre lo que Puerto Rico tiene para ofrecerte, escríbeme para orientarte.

Puerto Rico will need more than our prayers. Stay tuned for ways you can aid and help different communities in the aftermath. I will create a thread with the ones I see/hear about (feel free to DM) Let’s not forget about this next week. Recovery takes weeks, months, years…

PhD supervisors have two moods: