Antonella Dost
@nella_dost
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Postdoc @TheCleversLab @_Hubrecht | RESPIRE4 fellow @EuroRespSoc | primary human alveolar #organoids and COPD modeling
Utrecht, The Netherlands
Joined September 2020
Pre-print alert!.A primary human alveolar #organoid model that allows for 1) long-term expansion of progenitors; 2) AT2 maturation; 3) AT1 differentiation in defined media. Regenerating AT2s and AT1s show opposite responses to IFN-gamma! @TheCleversLab .
biorxiv.org
Chronic obstructive pulmonary disease is characterized by inflammation and emphysema, leading to progressive alveolar destruction. Currently, no therapies effectively regenerate the alveolar epithe...
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RT @TheCleversLab: The Clevers lab is represented at the #ERSCongress in Vienna, with @nella_dost presenting her primary human alveolar lun….
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Having a great time at the #ERSCongress in Vienna. Lots of great networking with my fellow @EarlyCareerERS members @carola_voss @TheCleversLab
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RT @paolapeinadof: What a great opportunity to participate in #LSC2024 and meet other RESPIRE4-MSCA fellows!🤗 I cannot feel more grateful f….
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RT @dzlacademy: A #RESPIRE4 Fellow meetup at the @EuroRespSoc #LSC2024 was convened in #Estoril 🇵🇹 today by ERS Fellowships & Awards Direct….
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RT @aaronlavelmoye: My final paper at @BCHStemCell @harvardmed @Carlakimlab merges cancer, inflammation and cell plasticity - we identified….
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Exciting news! As Guest Editor for @jovejournal, I'm organizing a methods video collection on “Studying Lung Cancer Using 3D In Vitro Models“. Interested in contributing? Submit your abstract now!" #lungcancer #3Dinvitromodels #organoids .
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RT @TheCleversLab: Rare cell type in the spotlight: Transcriptomic profile comparison reveals ionocyte core signature across multiple mamma….
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We are delighted to announce that our review on macrophages in lung cancer has been published in @eLife. It was a pleasure to work on this with @katarinabal and @HansClevers. @TheCleversLab @_Hubrecht #organoids
elifesciences.org
As macrophages are involved in various aspects of non-small cell lung cancer development and progression it is crucial to develop appropriate 3D co-culture platforms for modeling immune cell-tumor...
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Fantastic EMBO Organoid conference #EESOrgan, thank you to the organizers for such a smooth event with (almost) no technical issues and plenty of networking opportunities.
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Out today in the new issue @CellStemCell: Our Resource exploring early-stage lung cancer.Thank you for the preview Jihan Osborne, PhD, and John Minna, MD. @aaronlavelmoye @Kottond .#lungcancer #lungbiology #stemcell #singlecell #cancer .Free access link:
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Great collaborative effort from the Carla Kim lab, @Kottond lab, Yanagawa and Dubinett labs, combining organoid models, mouse models, and human patient data to study early stage lung cancer. Thanks to my co-first author @aaronlavelmoye and @CellStemCell .
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RT @aaronlavelmoye: Out now @CellStemCell! Using 3 systems, patient samples, and @10xGenomics scRNASeq we found that early-stage lung cance….
cell.com
Early-stage lung cancer is poorly understood. Dost, Moye et al. introduce new organoid systems to model lung cancer. KRAS-expressing alveolar progenitor cells had reduced expression of lineage genes...
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