Matt Birnie
@mtbirnie
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Neuroscientist, Cyclist, Runner
| @BristolUni | @UCIrvine |
Joined July 2020
Excited to be able to finally share this work with everyone! Histone variant exchange, where histone protein are swapped for one another, is an interesting mechanism for gene regulation. We show it plays a key role in cocaine responses.
Please see this exciting publication by @PhilippMews and others which describes a novel "chromatin scar" induced by cocaine, lasting depletion of H2A.Z from nucleosomes, in nucleus accumbens medium spiny neurons that drives gene priming and drug relapse. https://t.co/lZi9rg5cj4
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Early-life adversity and life-long memory issues? Everything (well, almost) you might wish to know, in humans and animals. Circuits, epigenetics & >200 source references. With the amazing @mtbirnie
https://t.co/QqgNfq8nzS
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We're looking to fill a postdoc to work on traumatic stress plasticity of inhibitory circuits in the basolateral amygdala, funded by a VA grant to work in new state-of-the-art VA facility in New Orleans. Looking for hard-working, ambitious individual with patch clamp experience..
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Apropos of...nothing in particular....here is some trivia to start your week off & flex your cannabinoid knowledge💪🧠 Which of the below ligands does NOT bind to the cannabinoid 1 (CB1) receptor?
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Are you a postdoc or student working on a neuroendocrine research project?🧠🔬 💸Get up to £7,000 support for consumables/other research costs to enable you to carry out the best possible neuroendocrine research project. Deadline 1 May More: https://t.co/9Ozmi9Oeqk
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I'm so proud to share my Ph.D. work from @OferYizhar's lab, now on bioRxiv. We developed a new approach for transcranial optogenetic silencing in untethered and freely-behaving pups, exploring the role of oxytocin in early-life social behavior >> https://t.co/I3E2KcVYWK
biorxiv.org
Oxytocin is essential in shaping social behavior across the lifespan. While the role of oxytocin signaling in parental care has been widely investigated, little is known about its function in social...
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APPLICATIONS ARE INVITED for the Editor-in-Chief, Translational and Clinical strand, JNE This is an exciting time to become involved in the ongoing global development of our prestigious Journal. Apply by 23 November: https://t.co/XKJXUH6iM2
@JNE_Editor
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I thought about it. Not sure how feasible this is because of the visa bureaucracy but I’m happy to extend my invitation to 3 international researchers from Israeli labs working on either Neuroimmunology, Immunology or neuroscience. Please reach out and I will do my best to
If you’re collaborating with Israeli PIs, think about whether you could invite one of their international trainees for a short stay so that they can get some work done while they are unable to return to their home lab.
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Congratulations @hotmasupton, @ederzavala, @staffordlightma et al on this fundamental study measuring #circadian hormone levels in ambulatory humans! Endless opportunities to identify disrupted rhythms in #metabolic #inflammatory #mental disorders https://t.co/DRjccQ52Qa
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🚨 Researchers @AtSpared show that early life adversity in mice leads to long-lasting effects in a mouse version of a human reward task: "Early life stress in male mice blunts responsiveness in a translationally-relevant reward task" 👉 https://t.co/Lc6cribldU
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📢 MULTIPLE NEUROSCIENCE FACULTY POSITIONS AVAILABLE! 📢 Looking to set up your first lab or bring your existing research to sunny Devon? Lecturer and Senior Lecturer positions available now at @UniofExeter @ExeterMed. Join us!
exeter.ac.uk
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Wow, the USA Brain Bee was intense! 😲 So many brilliant students from across the country! It was an honor to help host it at @ucicnlm with @manuellayassa @winnyning and all our volunteers 😍 (I have ~0 pictures though because I was running around too much 😂) #USAbrainbee
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Have you submitted your ground-breaking research yet? Don’t wait until the last minute - the deadline is tomorrow! Submit your abstract today 👉 https://t.co/kGukrrDRbt
@SENC_ @JovInvest_SENC @JuanLerma1 @TheBaleLab
#IBRO2023 #neuroscience #researchers #abstractsubmission
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📢I am giving a free public lecture in Brighton soon, on Tuesday 25th April, 6.30pm 📢To book a ticket, double click 👇 https://t.co/0yXM3By1mG
#BNA2023
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There is still time to submit abstracts & #travelawards & early registration still open for #EBPS2023 @EurBehavPharm! https://t.co/AcEbbh6iEY Please share widely for those interested in #behavioralneuroscience. Fantastic conference for trainees to expand their #global network.
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Excited to share a new Hill lab paper on how genetic variance in FAAH, the enzyme that metabolizes the endocannabinoid anandamide, can influence feeding responses to orexigenic and anorectic signals, that just came out in @eLife
https://t.co/yaGxIfYvBo
elifesciences.org
A genetic knock-in mouse model reveals that the endocrine state governs the effect of the common fatty acid amide hydrolase C385A variant on body weight through a hypothalamic-mediated mechanism.
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Long-term use of #steroids could impair memory finds a new study that showed even a relatively short course of the drug led to impaired memory performance when carrying out a memory and learning-related task.🧠 Read more👉 https://t.co/uaI1V2Asr7
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Ever wondered why chronic steroid use can cause #dementia? Excited to share our paper with @staffordlightma @BeckyConwayCam2 @BristolUni out today in @PNASNews ! Check it out below⬇️ https://t.co/7ewBKvehOn
pnas.org
Disrupted circadian activity is associated with many neuropsychiatric disorders. A major coordinator of circadian biological systems is adrenal glu...
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Pls Check out the lab's preprint: @dilithium21 Used new GRAB-NE sensors from @yulonglilab, measuring NE and DA release, GCaMP responses, & interactions between tonic & phasic firing modes. https://t.co/Sann7wHrs5
#NIMH @UWAnesthPainMed @NAPECenter @UWPharmacology
biorxiv.org
Catecholamine signaling is thought to modulate cognition in an inverted-U relationship, but the mechanisms are unclear. We measured norepinephrine and dopamine release, postsynaptic calcium respons...
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