Neuropsychopharmacology
@npp_journal
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Neuropsychopharmacology (NPP) is an official peer-reviewed publication of @ACNPorg. We report discoveries and promote training & outreach initiatives.
Nashville, TN
Joined February 2017
This paper, led by former NPP intern Hayley Thorpe, tracks the impact of our NPP social media efforts (which we are now sharing on social media - so meta!) on facilitating engagement with articles and driving website traffic https://t.co/6Kup81wPxv
nature.com
Neuropsychopharmacology - Optimizing social media initiatives to promote Neuropsychopharmacology (NPP) publications
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This recent study found diverse motor signs in late-life MDD are linked to changes in synaptic density & gray matter in subcortical basal ganglia-thalamic structures. Some motor signs also related to widespread gray & white matter changes across the 🧠 https://t.co/dzIF2Wqvta
nature.com
Neuropsychopharmacology - Motor signs in late life depression relate to altered subcortical synaptic density and gray matter volume: an 11C-UCB-J PET-MR study
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Don't miss this new review from @CodySiciliano & @ZFarahbakhsh 👇
Excited to share our @npp_journal review on kappa opioid receptors. @ZFarahbakhsh & I cover the canonical and dissenting viewpoints in parallel. In particular, we push back on the idea that the essential function of the kappa system is to encode aversion: https://t.co/IOXgBMtqnY
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Last Chance! ACNP Career-Spanning Mentorship Award applications are open for the ACNP 64th Annual Meeting: January 12-15, 2026, Nassau, Bahamas. Deadline to submit is November 6th at 5:00 pm Central. For more information, visit: https://t.co/obTzxWg702
#ACNP2026
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This recent study finds that DMT reshapes the 🧠’s connectome harmonic repertoire, mirroring effects of psilocybin, LSD & ketamine, with entropy and energy spectrum changes closely tracking the intensity of participants’ subjective experiences 🍄💊 https://t.co/txGrsEEZdg
nature.com
Neuropsychopharmacology - N,N-dimethyltryptamine effects on connectome harmonics, subjective experience and comparative psychedelic experiences
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🎉 Congratulations to our Social Media Editor, Dr. Leah Mayo, on being named to Avenue Calgary’s Top 40 Under 40! Her research on stress, cannabinoids, psychedelics, and mental health continues to make an impact - in and beyond the lab. 🔗
avenuecalgary.com
Leah Mayo’s groundbreaking work developing therapeutic applications of psychedelics and cannabis-related drugs as the first research chair in psychedelics in Canada is advancing mental health care.
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4️⃣ Hyper-maturity and accelerated aging in the hippocampus Mouse models of anxiety and depression showed “hyper-mature” hippocampi with aging-like gene expression.
nature.com
Neuropsychopharmacology - Hyper-maturity and accelerated aging in the hippocampus of mouse models of neuropsychiatric disorders with anxiety-like behavior
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3️⃣ DKK2 and hippocampal neurogenesis Loss of DKK2 disrupted context discrimination and Wnt signaling balance. JNK inhibition rescued these deficits, highlighting DKK2’s role in hippocampal neurogenesis and behavior.
nature.com
Neuropsychopharmacology - DKK2 contributes to context discrimination and adult hippocampal neurogenesis by suppressing Wnt/PCP signaling
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2️⃣Hierarchical critical periods in neurodevelopment Review proposing “hierarchical critical periods” across the cortex - from sensory to association areas - shaping vulnerability and resilience across childhood and adolescence. https://t.co/NJe6P3oCiO
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1️⃣ Integrating multi-polygenic scores for antidepressant outcomes Multi-polygenic scores (for insomnia, pain, inflammation) predicted poorer SSRI response in East Asian patients - a step toward personalized antidepressant treatment. https://t.co/lDGZUo9rM7
nature.com
Neuropsychopharmacology - Integrating multi-polygenic scores for enhanced prediction of antidepressant treatment outcomes in an East Asian population
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New week - new luck - new TWiNPP 🧠 #ThisWeekInNPP four studies on genetics, development, neurogenesis, and neuropsychiatric models. 🧵👇
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This recent 🔥 Hot Topic 🔥 highlights transcranial focused ultrasound stimulation as a novel, non-invasive way to target the subcallosal cingulate cortex in treatment-resistant depression, with early studies showing rapid, lasting improvements in mood https://t.co/0oDFkxNsa2
nature.com
Neuropsychopharmacology - Brainwaves meet soundwaves: ultrasound stimulation for treating major depressive disorder by targeting the subcallosal cingulate cortex
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“Whether it be the suppression of a violent head jerk or a guttural grunt, my Tourette Syndrome forces me to do battle every second.” Read Thomas White’s searing account of his life with Tourette Syndrome 👇 https://t.co/leKdqZMDke
nature.com
Neuropsychopharmacology - Louis Armstrong Stadium erupts as thousands of fans cheer the entrance of Tommy Haas and Richard Gasquet. As these tremendous athletes stride past me, I stiffen in my navy...
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Apply Today! ACNP Career-Spanning Mentorship Award applications are open for the ACNP 64th Annual Meeting: January 12-15, 2026, Nassau, Bahamas. Deadline to submit is November 6th at 5:00 pm Central. For more information, visit: https://t.co/obTzxWg702
#ACNP2026
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One nation under God you say A million other people standing next to me Pleading for salvation from a tyranny One nation under God you say On the one hand I am proud to be From a country that appears to be Built on freedom and democracy Just don’t look too close or you’re bound
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Kicking off Halloween weekend early by giving our intern the account’s password… spooky 👻👻👻
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ACNP Early-Stage Investigator Assistance Program applications close TODAY for the 64th Annual Meeting: Jan. 12-15, 2026, Atlantis Paradise Island Resort. You must already have an in-person invite or be registered to attend the meeting in person to apply. https://t.co/McsGVnbh0b
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🎉 Congratulations to our Social Media Editor, Dr. Leah Mayo (@MayoOnTheBrain), on being named to Calgary’s Top 40 Under 40! Her research on stress, psychedelics, cannabinoids & mental health continues to make an impact — in and beyond the lab 🔗
avenuecalgary.com
Leah Mayo’s groundbreaking work developing therapeutic applications of psychedelics and cannabis-related drugs as the first research chair in psychedelics in Canada is advancing mental health care.
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This recent 🔥Hot Topic🔥 discusses how the exposome- the sum of internal, external, and contextual exposures- shapes adolescent neuroplasticity & mental health risk and could present a novel opportunity to guide strategies to promote adolescent 🧠health https://t.co/RXjxYmPHwO
nature.com
Neuropsychopharmacology - The exposome and the developing adolescent brain: understanding mechanisms of neuroplasticity
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This recent study found that caffeine produced minimal changes in THC’s subjective, performance, or metabolic effects In contrast, CBD ⬆️ THC-induced “drug high,” performance impairment, & plasma THC and 11-OH-THC levels ☕️💊 https://t.co/VQTfYLX96T
nature.com
Neuropsychopharmacology - Effect of caffeine and cannabidiol (CBD) co-administration on Δ9-tetrahydrocannabinol (Δ9-THC) subjective effects, performance impairment, and pharmacokinetics
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In this recent paper, maternal separation stress produced dysregulated noradrenergic activity in the locus coeruleus (LC) across the lifespan, which disrupted LC regulation of coping strategies in adulthood https://t.co/cjxw81eoHn
nature.com
Neuropsychopharmacology - Maternal separation disrupts noradrenergic control of adult coping behaviors
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