Maria P. Fernandez
@mariadelapax
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Neurobiologist I Neuronal control of behavior in Drosophila Biology Department, Indiana University Bloomington @IUBiology Bluesky: @mariadelapax.bsky.social
Bloomington, Indiana
Joined October 2010
Our latest manuscript, published today in #PLOSGenetics: .The Drosophila circadian clock gene cycle controls the development of clock neurons
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RT @ErikHerzog: Happy end of Daylight Saving Time. For health, safety, and economics let’s keep Permanent Standard Time. @SRBR_Outreach @S….
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RT @drEllaGutierrez: Our new preprint is out! 🪰 ⬇️.📍The oviposition inhibitory neuron (oviIN) is a hub in the oviposition circuit receiving….
biorxiv.org
Understanding how neural circuits integrate sensory and state information to support context-dependent behavior is a central issue in neuroscience. In Drosophila, oviposition is a complex process in...
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RT @Neely_Lab: Turn down the pain, turn up the gain: Our new paper on peripheral pain targets is out @GeneticsGSA. Work by Zina Hamoudi and….
academic.oup.com
Chronic pain has an enormous impact on the quality of life of billions of patients, families, and caregivers worldwide. Current therapies do not adequately
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RT @MArbeitman: The FlyBoard is happy to announce the call for nominations for the Drosophila Community Service Award. Please submit your n….
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RT @FlyBaseDotOrg: The Fly Board introduced a new Mentor-Mentee program, which aims to foster the development of early-career scientists by….
docs.google.com
We appreciate you taking the time and volunteering to be a mentor! To be a participating mentor, we request that you complete the survey to enable the program committee to match you with the most...
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So many great resources here, including neuropeptide/neuropeptide receptor (hello, PdfR) expression mapping and splitGal4 lines.
Finally, its out on biorxiv. Our labs collaboration with Rubin lab@Janelia building CX specific cell types, determining their neurochemical identities and screening them for sleep phenotypes. 7 years in making and hopefully a great resource for the community.
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3- Clk downregulation also leads to developmental effects on sLNv morphology.
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* I guess it is now an 'article', no just a 'manuscript' : ).
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2- This effect is due to a developmental role of cyc, as both knocking down cyc or expressing a dominant negative form of cyc exclusively during development lead to defasciculation phenotypes in adult clock neurons.
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Mini summary.Our results show that:. 1- Downregulating the clock gene cyc specifically in the Pdf-expressing neurons leads to decreased fasciculation both in larval and adult brains.
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RT @RAICYT_Ar: El desmantelamiento de la Agencia, corazón de la ciencia en Argentina, sigue avanzando. A la falta de nombramiento del dire….
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RT @RayesDiego: In @eLife: The ketone body β-hydroxybutyrate ameliorates neurodevelopmental deficits in the GABAergic system of daf-18/PTEN….
elifesciences.org
PTEN mutations disrupt inhibitory GABAergic signaling, causing neurodevelopmental defects that can be mitigated by β-hydroxybutyrate, which activates DAF-16/FOXO and may offer a therapeutic approach...
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RT @EricTopol: How important circadian rhythm is for promoting our health: a study of ~89,000 @UK_biobank participants with 13 million hour….
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RT @CSHLflycourse: New opportunity for you to “pay it forward” - don’t miss it!!! #mentoring #Drosophila #share_ur_wisdom.
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RT @biorxiv_neursci: Neuropeptide-dependent spike time precision and plasticity in circadian output neurons #biorx….
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RT @SatchinPanda: Listen to this incredible story of Prof. Charlotte Helfrich-Förster. She made a huge circadian rhythm discovery when she….
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