FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate:

This chilly autumn day brings the October #TechnicalAdvances https://t.co/s8kvAhst9P. If you'd like your paper with a new technique, resource,or reagent featured in an upcoming month, make sure to flag it when you #FTYP.

https://t.co/e1Tirvv3TO is back up.

Searches and tools are currently down for https://t.co/e1TirvvBJm. Our developers are working on getting us back up.

New #MetabolicPathway reports too: the GLUCOSYLCERAMIDE BIOSYNTHESIS https://t.co/hzT5vHcKic, the GPI-ANCHOR PROTEIN BIOSYNTHESIS https://t.co/Ssr3OYGEW5 and the DOLICHYL PHOSPHATE BIOSYNTHESIS https://t.co/ss8iuk1z7e pathways.

And some new family gene groups: SPECTRINS https://t.co/sKcnJPAhR6 and SINGLE VON WILLEBRAND FACTOR TYPE C DOMAIN PROTEINS

This FlyBase release features mitochondrial complex #GeneGroups: MITOCHONDRIAL INNER MEMBRANE PEPTIDASE COMPLEX, https://t.co/S9Ll4sk59w, MITOCHONDRIAL DEGRADOSOME https://t.co/M3zYfxBiUn and MITOCHONDRIAL PROCESSING PEPTIDASE

Also #NewInFlyBase for FB2025_04: You can now access the @alliancegenome.bsky.social BLAST service directly from the FlyBase toolbar at the top of every FlyBase page. The path is Tools>Genomics Tools>Fly BLAST @ Alliance.

More new bulk files: •Disease-implicated variants •Gene relationship comments •InterPro signatures •Representative publications •Chemical Synonyms •Curated Expression

New bulk downloads include: •Aberrations - gene deletion/duplication data •Split system combinations •Human disease model reports •Single Cell RNA-Seq Metadata •Gene model status and annotation comments •Antibody information (There's more!)

#FlyBase release FB2025_04 is live. There's a couple of major changes in this release. First, we've added many new bulk files to the Downloads page. https://t.co/olCXZxHfiO (you can find descriptions of the contents and format of each file here https://t.co/KE5Sbm7omW)

Model organism databases face budget cuts and closures https://t.co/TUFIdMTkbq @Nature

There's an update on the state of FlyBase on the https://t.co/e1TirvvBJm front page. You can contribute to FlyBase at this link https://t.co/IrQapPFJWR. We express enormous gratitude to the people, labs, groups, and foundations who have already helped us. #FlyBase #Drosophila

It's #TechnicalAdvances update time; the papers added in September are here https://t.co/kXORmUwVgT. Want your paper with with a new technique, reagent, or resource featured next month? Flag it when you #FTYP!

The results page, here shown for a BLASTX search, shows a graphical overview at the top of the page. The hit list beneath looks like the BLAST output you know and love.

or a search can be restricted to only Drosophila melanogaster databases. Once you enter a DNA or protein sequence in the search box, you'll be offered appropriate options for the nucleotide or protein databases you wish to search.

You can now search FlyBase and WormBase sequence data using the Alliance of Genome Resources BLAST server: https://t.co/eQsIzrDvSG The Fly interface allows searching against many arthopods, #FlyBaseTweetorial #BLAST

The FlyBase situation has made the national news

https://t.co/ZSXB50OycS Harvard Funding Cuts Endanger the Massive Fruit Fly Database That Powers Genetic Research

There are only 10 days left to register for EDRC 2025! Visit https://t.co/zLO8q1sjWb for more information. @edrc2025 @FlyBaseDotOrg @NeuroAlc @UniversidadMH @CSIC @drosospain

Fly folk: The Amazing and essential @FlyBaseDotOrg is in existential need due to Trump termination of the grant that supports this vital resource. Please donate to help keep Flybase alive. I just did. Info here on how to make a tax deductible donation: https://t.co/Tcob7QddZt