John Hogenesch
@jbhclock
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Professor of Pediatrics, Thomas F. Boat Chair, Human Genetics, Immunobiology, and Pulmonary Medicine, Cincinnati Children's and Professor of Molecular Biology
Cincinnati, OH; San Diego, CA
Joined October 2012
The Quest by Circadian Medicine to Make the Most of Our Body Clocks - The New York Times
nytimes.com
Researchers are trying to figure out the right hour of the day to do everything. Can their studies sync us up with better health?
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Why do heart attacks during the night cause less damage than during daytime? The role of neutrophils and circadian clock genes in reducing inflammation and injury @JExpMed in experimental model https://t.co/EhnI5BPD7V
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This is really gross. I know money is money, but I can’t imagine lowering your standards to the point of getting into bed with an organization as perfidious as the Boston Red Sox.
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7 years later and still reckless
Seven years after the first gene-edited babies were revealed, biotech startup Manhattan Genomics is reviving the idea of editing human embryos to make disease-free children.
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What happened the last time the U.S. tried permanent DST? 79% supported it beforehand, but after many dark winter mornings, support plunged to 42%. People didn’t like it! The most recent permanent DST bill failed, and history shows that's for the best. https://t.co/vLi2QTQ8Bb
smithsonianmag.com
A 1974 switch to year-round DST proved unpopular, with Americans expressing "distaste" for the long, dark winter mornings
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I feel like the NIH Biosketch format hasn’t changed lately. Should we do these in Swedish moving forward?
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Happy angioplastyversary #cmgsays
September 16, 1977, Andreas Gruentzig performed the 1st coronary angioplasty in Zurich. Below is the story, told by the 1st patient himself, Adolph Bachman, and his doctor, Bernhard Meier. This was the birth, not just of interventional cardiology, but a whole new branch of
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Robert Redford was my favorite, it’s hard to process that he is gone. His performances made more movies I love than anyone else, I’d take The Sting over any film for flawless perfection. We don’t expect famous people to also be good people but he was. He belongs to the ages
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A simple way to help reduce obesity and stroke? Stop the shifts in our clocks twice a year
pnas.org
Seasonal changes in time policy, such as switching between Standard Time (SDT) and Daylight Saving Time (DST), have been adopted by many countries,...
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RIP David Baltimore. To make a discovery directly challenging fundamental molecular biology so convincingly to win a Nobel Prize shortly thereafter is simply remarkable https://t.co/v4aqnyNfcS
@nytimes by @ginakolata
nytimes.com
He was only 37 when he made a discovery that challenged the existing tenets of biology and led to an understanding of retroviruses and viruses, including H.I.V.
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UAB and Children's of AL is looking for a new Division Director of Pediatric Neurology (come be one of my bosses!). We are consistently in the top 30 nationwide in Pediatric Neurology and have excellent subspecialties in: Epilepsy, Autism, and NMDs. Apply: https://t.co/XqHAdGQpZ7
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Sergey Brin and Gwyneth Paltrow presented the Breakthrough Prize in Life Sciences to Emmanuel Mignot and Masashi Yanagisawa for their groundbreaking discovery of the causes of narcolepsy and the development of treatments for sleep disorders. Their recognition underscores the
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I'm excited that @Jjiyeon_lee's 2nd paper from the lab is out in @NatureAging. We found that the circadian gene REV-ERBalpha regulates brain NAD+ by controlling CD38 in astrocytes. REV-ERB KO or pharmacologic inhibition mitigates tau pathology in mice.
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If you are interested in our research about discovering species with extremely low cancer rates or using ideas from integrated pest management to improve cancer therapy, ASU has a new podcast Lab Coat Optional that featured my work in an episode:
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@mattinwpb @mcuban This is just terrible. My wife and I have now stopped using our ‘pharmacy benefit’ for either of us as cost plus now carries all our meds and is cheaper, and allows for a 90 day supply. Our PBM-negotiated rate was 30 days max. What a PITA.
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