Marc Expòsit
@marc_exposit
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PhD student, Baker lab @UWproteindesign. Interested in synthetic biology and its impact in society. Sant Dalmaienc de la Universitat de Girona.
Seattle, WA
Joined March 2015
Cute story alert!🧵@Caltech two clueless office mates (@piraner & I) created a tool to control cells with ultrasound. As postdocs (@UCSF & @UWproteindesign), we teamed up again (with @majo__duran & @AdamChazin) to build a tool for engineered cell signaling
nature.com
Nature - A synthetic receptor platform that enables mammalian cells to respond to soluble factors allows specific signalling networks to be precisely controlled, with a variety of therapeutic...
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David didn’t just launch a field that's transforming science and soon, our lives—he did it while being an incredible mentor and a caring human. His dedication to his lab and students is just as worth celebrating. Cograts to David and to us at the @UWproteindesign!
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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I’ve always believed great science happens with great people. Couldn’t ask for a better team than Buwei, Green and Brian. Together, we created EndoTags, a de novo protein version of the foundational LYTAC system from the Bertozzi lab.@UWproteindesign
nature.com
Nature - Computationally designed genetically encoded proteins can be used to target surface proteins, thereby triggering endocytosis and subsequent intracellular degradation, activating signalling...
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I'm sharing my story in a difficult time for Palestinians and Lebanon, where we found refuge after being exiled from Haifa. I want to honor those who suffered the most and never got to live out their dreams—my grandparents, Jido Ali and Taita Khadejeh. I hope they’re proud (1/3)
The first episode of @BakerLabPodcast is live. Meet Mohamad Abedi, who went from being a Palestinian refugee to a postdoctoral researcher. His journey proves that science can be a creative and transformative process. Apple: https://t.co/kBk9SW7kDE Spotify:
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🚨 Front cover alert! 🚨 Scientists have found ‘fossil chromosomes’ in the remains of a 52,000-year-old woolly mammoth. With up to a million times more sequence, the scale of the discovery dwarfs ancient DNA and paves way to assemble genomes of extinct species! 🧬🌍 The work is
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Tenir més referents d'estudis en català hauria estat un recurs inestimable quan vaig col·laborar en la redacció de "L'edició genòmica i el seu impacte" amb la @SCB_iec 📄 https://t.co/EQ6ghesBK7
https://t.co/HFYolmUj4p
Quin plaer haver pogut col·laborar amb aquest equip per redactar l'informe "L'edició genòmica i el seu impacte". Si teniu curiositat per saber més de l'edició genòmica, no dubteu en fer-li una ullada a l'informe i a la xerrada: https://t.co/oSDAVHpLn3
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!! Iniciatives així són exemplars, no només com a referència terminològica, sinó també per facilitar l'accés directe i en català als resultats de la investigació científica.
🌟 Fita històrica per a la llengua! @NatureComms ha publicat un resum en català d'un estudi del #CRG liderat per @RodericGuigo i @Silvia_Torello, que descriu un mètode per a la seqüenciació completa de molècules d’ARN. 🔗 https://t.co/N7iA9H8GyK
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1/6 Can #AlphaFold learn from + & - labeled data to predict peptide binding better? w/ Phil Bradley @JustasDauparas @minkbaek @Mohamad_Abedi David Baker we present joint structure prediction-classification fine-tuning of #AF2 to classify pMHC binding.@UWproteindesign @fredhutch
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AI algorithms can now churn out predictions for the 3D shapes of proteins with a precision matching that of painstaking laboratory techniques. The programs, and the blizzard of protein structures they have revealed, are Science’s 2021 #BOTY. https://t.co/zBZlWr0fis
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New preprint! We came up with 2 methods to design de novo scaffold proteins to hold arbitrary functional motifs: hallucination (optimizing a seq against predictions of RoseTTAFold (RF)) and inpainting (recover masked regions of seq+struc.) 1/n
biorxiv.org
Current approaches to de novo design of proteins harboring a desired binding or catalytic motif require pre-specification of an overall fold or secondary structure composition, and hence considerable...
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A priori sembla un article inofensiu, que sembla alinear-se amb els objectius i valors que volem promoure des de les Young IT Girls. Ara bé, analitzem-lo una mica més en detall: Obrim fil.👇
Jefa de grupo en el Instituto de Bioingeniería de Cataluña (IBEC), explica cómo vive su experiencia como madre mientras desarrolla proyectos pioneros en la creación de mini-órganos artificiales
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I quina sort trobar la meva base complementària en tu
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Interesant: Without Code for DeepMind’s Protein AI, One Lab Wrote Its Own
wired.com
The Google subsidiary solved a fundamental problem in biology but didn’t promptly share its solution. So a University of Washington team tried to re-create it.
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Our paper on sci-Space, a spatially resolved version of sci-RNA-seq, is out today! Led by @srsrivatsan and @mregier13, Joint work with @JShendure and @kellystevenslab. (Art by @nigelsussman)
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Congratulations to Dr. @SRsrivatsan on a brilliant (and successful) thesis defense!! (@coletrapnell @uwgenome @UW_MSTP)
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Es un verdadero honor. Se lo dedico a mi padre, que nos dejó demasiado pronto. Él me enseñó a ver el mundo con curiosidad y me transmitió la sensación única de descubrir algo por primera vez.
Y el #PremioFPdGi Investigación Científica 2021 es para... César de la Fuente ¡Muchas felicidades @delafuenteupenn!
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D'un dissabte post vacuna a 38'5°C. El sol es ponia al teu jardí. Tu em parlaves de Seattle. Nosaltres.
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Fa just un any anava a la universitat per última vegada degut al confinament. Avui, un any després, m'han vacunat. Unes hores després han aturat la vacunació de #AstraZeneca #VacunaCOVID19
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