joe
@jtyler91
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Big dumb scientist. Biochemist/cell biologist
Joined March 2012
RT @J_Cell_Sci: Joe Tyler @jtyler91, Anthony Davidson, Vassilis Koronakis & team find that inhibition of PAK activity leads to the producti….
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RT @loxstoplox: Evaluating different deconvolution algorithms today. Behold the power of Richardson-Lucy!
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RT @CellCellPress: Now online! Genetically encoded reporters of actin filament organization in living cells and tissues .
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RT @biorxiv_cellbio: NHSL3 interacts with Ena/VASP proteins and the Scar/WAVE complex and promotes cell migration. .
biorxiv.org
Tight control of mesenchymal cell migration is important for embryonic development and its deregulation causes disease. It is driven by lamellipodia protrusion, the leading edge of the migrating...
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RT @GoryachevAndrew: A long-awaited mechanistic analysis of small GTPase biology and membrane pattern formation by the labs of Peter Bielin….
embopress.org
imageimageFormation of Rho GTPase activity patterns on the plasma membrane is key to numerous morphogenic processes in eukaryotic cells. This study employs a reconstitution approach to reveal the...
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In my opinion, one purpose of poetry is to express something that can’t be described within our ‘normal’ manners of expression. This is something that .Isn’t necessarily ’enjoyable’. Understanding is forged in contradiction… Reproduction of style is meaningless.
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RT @hannes_maib: 🚨Long term postdoc position available on the reconstitution of lipid kinases!🚨. Do you have a passion for protein reconsti….
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RT @melghazaly96: Excited to share my first contribution to virology, 1 year into my postdoc @towerslab! Together with my colleague @kate_m….
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RT @MCB_Sheffield: Congratulation Mubarak (Kai Erdman's lab) on passing your PhD viva today!!!! 🎉.@ScienceShef @sheffielduni .
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RT @PLOSBiology: Screen for novel kinase regulators by @Montse_Llanses @ERainero_lab &co shows that the α2β1 integrin/p38 signaling axis is….
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RT @MegPoxon: Great day at #actin2024 featuring lots of v cool talks, including our very own @rachellawson954, @ZheBao_Sheff and @jtyler91….
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RT @psychescope: Please enjoy this movie of local #microtubule disassembly inside the yellow circle using #optokatanin (magenta) with ER la….
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RT @Mramalie91: نور حب ماما وبابا غادرت متألمة، مثخنة بجراحها نحو السماء . Noor, a young child from Gaza, was killed by an Israeli bombin….
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RT @BBCWorld: Nearly 70% of Gaza war dead are women and children, UN says
bbc.com
A UN agency verified victims from a six-month period and said it found international law violations.
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We propose that PAK kinase activity acts to limit its own recruitment. In its absence, a hyper recruitment of PAK and PAK binding partners disrupts the excitable signalling pathways that regulate PI3K activation.
biorxiv.org
P21 activated kinases (PAKs) are involved in a wide range of functions from the regulation of the cytoskeleton to the control of apoptosis and proliferation. Although many PAK substrates identified...
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PI3K dependent rearrangement of the actin cytoskeleton following the addition of Class I PAK kinase-inhibitor. Please read about it in our pre-print!
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RT @cheesan_tong: Check out the latest work from .@WUMIN_LAB on the competition and synergy of Arp2/3 and formins in nucleating actin waves….
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