Joel Wagner
@joelpwagner
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Reimagining cancer medicine in Oncology Data Science @NovartisScience. Formerly @jacksonlab, @MITdeptofBE, @Cambridge_Uni, @UWMadison, @WVNYSCamp. He/him.
Cambridge, MA
Joined May 2015
Proud to see this work published based on a collaboration between @NovartisScience and @MGH_RI.
Recently published:.Dynamic evolution of fibroblasts revealed by single cell RNA sequencing of human #pancreaticcancer, by Slavica Dimitrieva et al. @hornheiko @davetingmgh @motazqadan @joelpwagner #PDAC #scRNAseq #openaccess
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RT @acambridgediary: A picture of Cambridge every day since 2010. (No 5000) Tuesday 5th December 2023. So here it is - my final picture of….
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RT @ac_palmer: New paper:. Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy, because they….
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RT @EricTopol: @hholdenthorp @juliettekayyem @meghas I could have highlighted every word. Thanks Holden 🙏
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Thank you to the scientists in industry and government making this a reality, and to the families of children participating in these clinical trials. Let's hope approval comes soon.
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RT @MSKEducation: There is 1⃣ more week to apply for our 2022 Summer Research Programs. This is a great opportunity for #undergraduate stud….
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If folks are looking for (K)N95 masks, I recommend For at-home covid tests, I had luck there or also More info on at-home covid tests here:
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RT @satijalab: Applications are open for the @cegs_ica summer internship program! Open to undergrads who are interested in learning about s….
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By exploiting aligned RNA-seq information, CaSpER avoided the need for explicit normal references, but it only provided categorical CNV calls and not continuous CNV values like the other two methods." 4/4.
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CopyKAT was unable to differentiate between normal samples and tumor cells except in narrow circumstances with intermediate numbers of unlabeled normal samples relative to tumor cells, but performed as reliably as InferCNV when provided with normal sample annotations. 3/4.
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From our Conclusion: "InferCNV was a robust method, provided that at least some (as few as 5) normal samples were provided. 2/4.
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Very happy to publish this work with Noemi Di Nanni (an Innovation Postdoctoral Fellow) and Joseph Boen (a summer intern) in the Oncology Data Science group @NovartisScience, comparing InferCNV, CopyKAT, and CaSpER methods for inferring copy number from gene expression data. 1/4.
Inferring copy number variation from gene expression data: methods, comparisons, and applications to oncology #bioRxiv.
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RT @Ginkgo: A wonderful opportunity to share with students or recent graduates in your life with a passion for synthetic biology, or public….
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RT @czbiohub: Tabula Sapiens is a first-draft single cell transcriptomic atlas of 2 human donors, 14 organs, and 150,000 cells. This colla….
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RT @jaybradner: Seeking curious scientists who are passionate about drug hunting for our Innovation Postdoctoral Fellowship. Apply asap to….
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On International Day of Women and Girls in Science, I am grateful for my past female mentors (esp. @mkemp_lab, Amariliz Rivera-Medina, @kristen_naegle, and Francesca Menghi), thinking about who I'm mentoring, and reflecting on my daughter's future. #WomenInScience.
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RT @kellystevenslab: @NIH R01’s from White scientists are funded at ~twice the award rate as Black scientists. @NIH has known this for a d….
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The #Oncology #DataScience group @NovartisScience is hiring! Come make a difference in the lives of cancer patients as part of the team: . @dfcidatascience @CompOncMSK @MITdeptofBE @cancersysbio @blkwomencompbio @womeninstat @LatinasinSTEM @sacnas.
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RT @dana_peer: Our first Human Tumor Atlas (HTAN) paper, jointly with the Rudin's lab on Small Cell Lung Cancer is ready. A stepping stone….
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