Stunning use of dTAG to study rapid dynamics of chromatin structure and cis-regulatory interactions at high resolution. Blueprint for studying mechanistic effects of TF degraders / modulators.

An inspired choice to lead a brilliant faculty of scholars. Congratulations, @mskcc CSO Ross Levine. I knew him when, and knew it then.

🚨FLIGHTSCOPE BLACK FRIDAY SALE $1,200 OFF Mevo Plus Golf Simulators!

How to Succeed in Biotech. Part 2 of this thoughtful and insight-rich reflection by Bruce Booth @LifeSciVC, on the eve of his 20th Altas-versary. Plain spoken and approachable, a high yielding reaction. Great read whether working at a small biotech or the largest independent

Go Bears!!!

Honored to keynote at Nucleate Summit 2025 with 500 brilliant entrepreneurs & scientists. The energy was electric—proof the future of biotech is in very good hands. #MyCompany

From decoding the genome’s “dark matter” to designing next-gen medicines, @HowardYChang is the ideal leader for @Amgen Research. Tackling the toughest problems in therapeutic science requires deep insights into human biology, creative new technologies in molecular biology,

Big news today: Phase 3 trial results published in @NEJM highlight @Amgen innovation in small cell lung cancer (#SCLC). 🔗Read how #MyCompany is reshaping treatment options: https://t.co/nzZHyZo7Rm

Amazing trip back home to Chicago for #ASCO2025, with our deeply dedicated Amgen oncology colleagues and our fearless leader Dr. @jsoriamd. Feeling very hopeful about the future of cancer care, our industry continues to rise to the generational challenge.

A new Nature Medicine study sheds light on why KRAS G12C–mutated NSCLC patients respond differently to treatment. Insights from two trials reveal molecular features and early blood-based markers that may predict outcomes. Grateful to our @Amgen team involved. #MyCompany

Hope you are having a restful and reflective Memorial Day weekend.

Grateful to join the Strategic Vision in Drug Discovery panel at #SDDS2025. At Amgen, we’re decoding disease at atomic resolution—advancing precision-based solutions grounded in deep human biology. Honored to share ideas with leaders pushing the boundaries of science.

Delighted to see LLF580 (efimosfermin alfa) acquired by @GSK, an FGF21 biologic for MASH. Thanks to @BostonPharm for believing in this idea. Third NIBR-born spin-out to be acquired for approx $1 bn or more.

At the @MilkenInstitute Global Conference panel, we discussed how AI, genetics & protein engineering are transforming drug discovery. From our research targeting Lp(a) to uncovering potentially protective mutations in obesity, we’re entering a new era of precision and

New in Nature Metabolism: CNS GIPR and GLP-1R are both essential for weight loss response to a GIPR-Ab/GLP-1 peptide–antibody conjugate in mice—and this signaling happens through brain regions that reach outside the blood–brain barrier. This provides a new perspective on central

This #DNADay, we’re celebrating DNA as a tool for innovation. Our DEL platform uses DNA barcoding to screen billions of molecules in parallel, accelerating discovery of small-molecule therapies targeting even the most elusive biology. #MyCompany

Tumor infiltrating clonal hematopoiesis associated with poor outcomes in solid tumors. Wonder if this is how IL1B inhibition seemed to improve survival from cancer in CANTOS…

Can you get too much of a good thing? Turns out ovarian cancer cells recurrently delete BRD4 regulatory elements to mute expression. So cool, even better from close friends.

These results show exciting clinical benefit & represent an important advance in #SCLC care for people in desperate need of more effective treatment options. Looking forward to sharing these findings with the scientific community as we strive to bring @Amgen’s immunotherapy to

Wonderful to be among the @TheMarkFdn leadership and community in NYC, taking vital signs and exchanging perspectives on progress in cancer therapy.

Another terrific outcome for a NIBR-born medicine. Congratulations to Rene Hersperger, Christian Bruns and all who worked to develop this gorgeous little electrophile.