Joe Chambers
@je_chambers
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Researcher @TheCIMR @Cambridge_Uni @MarciniakLab interested in cell biology, especially proteostasis and the ER. More active @joechambers.bsky.social
England, United Kingdom
Joined July 2017
Our paper is now out in @ScienceAdvances ! . We found that the disease-causing “Z” mutant of α1-antitrypsin “gums-up” the endoplasmic reticulum (ER) by forming a solid matrix, shown here by hypotonic shock… 1/8
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RT @DrSimonCook1: I have a BBSRC CTP PhD on protein kinases & cancer therapies available to start in Oct 2025. It is a collaboration betwee….
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RT @AvezovL: Our new paper is out, � on how a membrane-curving protein RTN4/Nogo links neurite regeneration and the….
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RT @AvezovL: 🚨With @AbellJonny & @Kosloverlab we are excited to organise “The Endoplasmic Reticulum Structure and Function Across Cell Typ….
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Brilliant news! Congratulations Marina!.
Congratulations to Marina for being awarded the Corday-Morgan #RSCPrizes for the development of unique probes and methodologies in fluorescence imaging! 🎉🔬
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RT @Alex_Doune: Only two days left to apply to join my new lab at the University of Manchester @MCF_UoM @FBMH_UoM!. #PleaseShare #Applynow….
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RT @Sharpe_Lab: We're starting to recruit postdocs to work on this exciting ERC (now UKRI) project. Please get in touch if you would like t….
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Fantastic opportunity to work with a brilliant scientist using really innovative approaches. Apply!.
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RT @CamillaGodlee: I am hiring a research assistant for my lab working on host-pathogen interactions of bacterial infections. Please send….
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RT @ReidLab_HSP: If you're interested in ER morphology and lysosome function in neurons then check our new BioRxiv paper out:.Atlastin-1 re….
biorxiv.org
Mutation of the ATL1 gene is one of the most common causes of hereditary spastic paraplegia (HSP), a group of genetic neurodegenerative conditions characterised by distal axonal degeneration of the...
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RT @DPhaz: Delighted our paper on oxygen tension in cell culture is now out in @embojournal. Particular congratulations to @joycelyntsi (se….
embopress.org
imageimageCell culture is considered a microenvironment with high oxygen. Here, terminally-differentiated cells are shown to be deprived of pericellular oxygen in standard culture systems. mandating...
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RT @AvezovL: Our📰 in PNAS now on how the ER shaped as nanoscopic pipework powers Ca2+ firing. Explains why ER is shaped as a tubular networ….
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RT @AvezovL: Luminal transport through intact endoplasmic reticulum limits the magnitude of localized Ca2+ signals | now our in PNAS https:….
pnas.org
The endoplasmic reticulum (ER) forms an interconnected network of tubules stretching throughout the cell. Understanding how ER functionality relies...
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Come and work with an amazing scientist on amazing questions at the amazing @TheCIMR. It's a no-brainer! Apply!.
🚨 JOB CALL!!! 🚨. If you’re interested in neuronal cell biology, come and work with us to use custom imaging and omics tools to study organelle contact sites in neurons. Please RT friends‼️. Open calls for a @wellcometrust funded Post doc and RA position listed below…
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RT @lippert_lab: If you're interested in doing a PhD, postdoc or looking for an RA position in Germany doing fun microscopy and cool immuno….
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Thrilled to see Jonny getting his lab up and running! Exciting times ahead, so keep your eyes peeled if you're in the market for PhD, postdoc or technician positions to do great science!.
🍻🍻🍻Well folks…some great news to share. Incredibly happy to announce that I’ll be starting my group @TheCIMR in Feb2024 with funding from a @wellcometrust CDA. A massive thanks to CIMR and my various mentors @ProfKHarvey, @JLS_Lab, Craig Blackstone and Peter St George Hyslop!.
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RT @melissagammons1: So incredibly excited to join @TheCIMR as a @wellcometrust funded CDA fellow. Cannot express my gratitude enough for t….
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RT @RachelSEdgar: We’re excited to share our work describing how formation of fluid assemblies called biomolecular condensates buffers intr….
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RT @ONeill_Lab: In a departure from biological rhythms, we’re excited to share our work describing the role of macromolecular assembly & co….
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Incredible work from the @DeriveryLab, led by @_JosephWatson & @Lara_K_Kruger ! Summarised in this great thread.
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