 
            
              Iain Tan, NCCS/GIS/Duke-NUS/STCC
            
            @iaintan_mdphd
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              Husband, Father, GI (Colorectal) Medical Oncologist & Scientist. Genomics | Immunotherapy | Diagnostics | Population Health #Blessed #Grateful
              
              Joined March 2022
            
            
           Delighted to work with @shyam_lab, @SabineTejpar, Joanito & many talented colleagues on our paper, using insights from single-cell & bulk -omics to propose an update to CMS classification of colorectal cancer, in @NatureGenet 1/  https://t.co/kStHkikbCh 
          
          
                
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             Great stuff @EvelynWongYT ! 
           Highlight of any conference is always the in-person connection with the global GI community! Always grateful for your encouragement and suuport @KaiKeenShiu
            
          
                
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             Highlight of any conference is always the in-person connection with the global GI community! Always grateful for your encouragement and suuport @KaiKeenShiu
          
           Hey @EvelynWongYT you did a great 1st #GI25 presentation and Q+A. Good luck for your talk at JSMO this year too 💪👏👏 
            
                
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             I agree, This is ridiculous! Cancer & Cancer research transcends politics. Cancer Research saves lives! Cancer Research illuminates knowledge. To all my fellow cancer researchers, Keep the faith! 
           We were just notified all @NIH @NCICTEP_ClinRes @NCI meetings are now CANCELLED. Investigators PLS continue your hard work and dedication to make a difference. #Cancer is indifferent to politics and impacts everyone. @asco #ASCOGI25 #CancerResearch
               https://t.co/uKw1UJJviN 
            
          
                
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             Grateful for the opportunity to work together with Daniela, @AndrsHidalgo16 @lai9uan to bring you our review on adaptations of neutrophils in cancer! We are really excited about the concepts we brought out in this review and hope you have as much fun discussing it as we did! 
           Hot off the press, our review article is out @ImmunityCP ! It has been a super enjoyable process collaborating with @AndrsHidalgo16, #DanielaCerezoWallis and @im_mel_nology to put this article together. #ThePowerOfMany Link to article:  https://t.co/TDR07YBhXo 
            
            
                
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             A monumental work to start 2025! @JCI_insight Led by @BEI506 and global team 🇭🇰🇨🇳🇸🇬 We uncovered the link between germline SNPs & TIME of #NPC #nasopharyngealcarcinoma - RPL14 that modulates the EBV life cycle - SELE that modulates the TIME  https://t.co/cIZbeHviRU 
          
          
                
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             We’ve done a lot of single cell work on colorectal cancer, but as Grace Yeo from @astar_gis showed at #HCA2024GM, spatial omics can still uncover cell states we didn’t know about. Plus domains, signaling, integration with pathology, etc. And the technologies are getting better … 
          
                
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            #ACORD24 throughly enjoyed the one week intense protocol writing workshop. Writing a full protocol in a week was intense but the opportunity to network for international collaborations was amazing! #multicentre #clinicaltrials
          
          
                
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             No. HaNSA isn't the name of a Korean girl band🤣 It's the Head and Neck Sarcoma Assessor! This helps guide clinicians managing these rare cancers make treatment decisions. Scan the QR code to try this out for yourself!  https://t.co/KLuMU92oLs 
            #sarcoma #rarecancer #CTOSTweetos
          
          
                
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             We recently described a unique TME in gastric cancer peritoneal metastases. To address this, we probably need combination locoregional and systemic therapy. We describe for the first time: PIANO trial, combining PIPAC oxaliplatin with systemic nivolumab.  https://t.co/3cOM5kKUbT 
          
          
                
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             Pleasure speaking on individualisation of induction and concurrent systemic tx in LA-NPC #ESMO2024 with @PBlanchardMD Nice to see many colleagues young and seasoned at the audience! 😁 @herbloong
            #ESMOAmbassadors
            @myESMO
          
          
                
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             ⚡️Early-onset Colorectal Cancer! An incredible showcase of EOCRC research by @KimmieNgMD. From EORTC work, Biobanks and longitudinal cohort study to the actual implementation of a service catered for EOCRC. More work to do - modelling, economics, productivity! @OncoAlert #ESMO24
          
          
                
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            @MyriamChalabi 💥 smashing it at #ESMO24 with #NICHE2 showing 100% 3 years DFS! But what is fascinating is the #ctdna data that she presented! Indeed: can ctDNA predict pathCR! #ESMO24 @OncoAlert
          
          
                
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             Plenary 2: How AI will really transform cancer care. Don’t miss the dynamic duo at 12:00 today ! 
          
                
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             Excited to share our work on city-wide metagenomic surveillance of hawker centres in Singapore! w/@macadology Several surprising findings here ... see thread  https://t.co/q8fCeajxNk 
          
          
                
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             This could be an important study --Olanzepine for moderately ematogenic chemo 
          
                
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             Indeed, great job spearheading this! ASCOBT covers very important and timely topics that will both describe the near term developments & shape the medium term future of oncology! 
           My take on #ASCOBT24 and why this is a meeting not to be missed and will only grow from strength to strength! @lillian_siu @ASCOPres @ASCO ASCO Breakthrough Will Explore Artificial Intelligence, Novel Therapeutics, and Health Equity 
          
                
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             Ecstatic and proud to share the NICHE-2 results, now published in @NEJM. Out of 111 pts, 95% had an MPR , and 68% a pCR after only 4 weeks of #neoadjuvant #immunotherapy. Grateful to the pts and colleagues who made this possible. @HaanenJohn
             https://t.co/h7xgmjOfjz 
          
          
                
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            #ASCO24 Honoured and proud on behalf of my team to have presented the first results of NEOPRISM-CRC. More to follow 🧬🔬📖 @KristenCiombor was a fantastic+ insightful discussant with astute questions from Romain Cohen @michael_overman @ILSONDavid, afterwards + online too🤨☕️💻🙏
          
          
                
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             Great job @VairavanL ! Glad to be part of this important piece of work. We generated benchmarking data using tumor alliquots with different degree of degradation (time on ice). ctQC removes low quality cells to reveal true biological signals from noise. 
           We propose ctQC(  https://t.co/hm2OfLoDqs),  a data-driven method to filter low-quality cells from scRNA & spatial omics data! Apart from empty droplets it efficiently eliminates soup/debris & damaged cells improving downstream biological inferences. Comments & suggestions welcome! 
          
                
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