Jinxin BEI
@BEI506
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Our new Cell study: Systemic immune activity occurs during human immune system maturation https://t.co/Sjd90D7bk1 Thanks and congrats to all collaborators.
cell.com
Profiling of immune cells from consecutive developmental time points in second-trimester fetuses and adults reveals that immune activation, immune tolerance, and hematopoiesis occur in a systemic way...
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Online: EB virus hijacks histone demethylase machinery to drive epithelial malignancy progression through KDM5B upregulation EBV stimulates KDM5B expression via interactions of EBNA1 (latent gene) and BZLF1 (lytic gene) on KDM5B promoter. https://t.co/tDgtGaXiV9
nature.com
Signal Transduction and Targeted Therapy - Epstein-Barr virus hijacks histone demethylase machinery to drive epithelial malignancy progression through KDM5B upregulation
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our epigenetic study on another virus related cancer -- Cervical Cancer JCI - Super-enhancer-driven EFNA1 fuels tumor progression in cervical cancer via the FOSL2-Src/AKT/STAT3 axis https://t.co/d2mlbZ0qA1 Thanks to our team and collaborators!
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Novel NPC risk gene! Integrative Transcriptome-Wide Association Study With Expression Quantitative Trait Loci Colocalization Identifies a Causal VAMP8 Variant for Nasopharyngeal Carcinoma Susceptibility https://t.co/w17jfbhjNm Thanks to all collaborators!
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Published in JCI. We call for attention to study genetic effects on tumor microenvironment components in nasopharyngeal carcinoma https://t.co/nGMrgNKRaC Thanks for invaluable supports from our collaborators. A good start for a Happy New Year!
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Using NPC as a model, our recent study delineates Tertiary Lymphoid Structure at single-cell and spatial resolution, providing insights into cancer immunoevasion and immunotherapy. With more than two years peer-review process! Grateful to coauthors! https://t.co/5mnyOICe9k
nature.com
Nature Communications - The interactions between tertiary lymphoid structures (TLS) and tumor cell aggregates remain to be investigated. Here, single-cell and spatial transcriptomics reveal the...
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Single‐Cell Analysis of NK/T cell lymphoma Paper: https://t.co/p0jYKgEhmm LinkedIn https://t.co/O2P0eoQhgF Facebook https://t.co/ELwPdK6lfE
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Research Publication Social Media Publicity LinkedIn https://t.co/O2P0eoQhgF Facebook https://t.co/ELwPdK6lfE
linkedin.com
#AMCDiscoveries To better understand the origins of the heterogeneity, researchers from National Cancer Centre Singapore (NCCS), Singapore General Hospital (SGH) and Duke-NUS Medical School conducted...
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-Integrating in-house and public single-cell transcriptome datasets -Another nice collaboration experience https://t.co/WeZV02xzxQ -Figure 1
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Comparative single‐cell RNA sequencing analysis of immune response to inactivated vaccine and natural SARS‐CoV‐2 infection - He - 2024 - Journal of Medical Virology - Wiley Online Library https://t.co/WeZV02xzxQ A second work on COVID-19. Thank everyone who provided support.
onlinelibrary.wiley.com
Uncovering the immune response to an inactivated SARS-CoV-2 vaccine (In-Vac) and natural infection is crucial for comprehending COVID-19 immunology. Here we conducted an integrated analysis of...
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The first single cell transcriptome analysis on NK/T- Cell Lymphoma: Pivotal role of EBV to drive malignant transformation of NK/T cells, establishing immunosuppressive tumor microenvironment of NKTCL. https://t.co/p0jYKgEhmm
advanced.onlinelibrary.wiley.com
Single-cell RNA-sequencing analysis and functional investigations uncover the pivotal role of EBV, particularly the viral gene LMP1, in the malignant transformation and progression of NKTCL. Malign...
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"Large-Scale Whole-Exome Sequencing Association Study Implicates Genetic Effects on Viral Oncogenesis and TME in Nasopharyngeal Carcinoma" : Crucial interplay between genetic variations and essential elements of TME (EBV&non-cancer cells) More at https://t.co/df0BIJtdSD
#medRxiv
medrxiv.org
Nasopharyngeal carcinoma (NPC) presents a substantial clinical challenge with limited understanding of its genetic underpinnings. Here we conduct the largest-scale whole-exome sequencing association...
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