Douglas Dyer
@douglaspdyer
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he/him, chemokines and the glycocalyx in health and disease at the Wellcome Centre for Matrix Research UoM @douglaspdyer.bsky.social
Joined September 2012
Excited to see the peer reviewed version of @MegTriesScience PhD work on the cover of Science Signaling, great explanation thread below
science.org
Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate.
Excited to share that my first first-author paper is now on @biorxivpreprint ! Here we’ve shown that leukocytes have a heparan sulfate glycocalyx that regulates their recruitment into skin during inflammation 🦠 🏃🏻♀️🩸 @douglaspdyer @SaundersLab1
https://t.co/iCL5i3P2Ut
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Leukocytes possess their own glycocalyx that contains heparan sulfate and regulates their recruitment to sites of inflammation, according to results from a mouse model of #psoriasis. @MegTriesScience @LydiaBeckerIII @douglaspdyer
https://t.co/mwkI1hUPYg
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@cosmos_atom_ @ScienceMagazine @scisignal Haha, spot on! Leukocytes tweak their surface glycans (that "coating") during inflammation like psoriasis, signaling other immune cells to join the fight at the site. It's like a cellular flare signal. Science keeps surprising!
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@ScienceMagazine @scisignal @grok so basically, cells are just flexing their coats during a flare-up? wild.
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@ScienceMagazine @scisignal Research shows leukocytes adjust their coatings: my immune system dresses better for parties than I do.
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Read the latest on monocyte protection during intestinal damage from @douglaspdyer and colleagues
mucosalimmunology.org
Radiotherapy (RT) is essential in treating abdominal and pelvic cancers but often damages the healthy tissues, particularly the intestines, leading to radiation-induced toxicities with limited...
CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity https://t.co/73qOTM9Y6V
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Read the latest on monocyte protection during intestinal damage from @douglaspdyer and colleagues
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New findings show that leukocytes have a surface “coating” that can be modified during inflammatory conditions, such as #psoriasis, revealing how these immune cells are recruited to sites of inflammation. @MegTriesScience @LydiaBeckerIII @douglaspdyer
https://t.co/mwkI1hUPYg
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New @SciSignal findings show that cells called leukocytes have a surface “coating” that can be modified during inflammatory conditions, such as #psoriasis, revealing how immune cells are recruited to sites of inflammation. https://t.co/lOzjyL46sU
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My PhD work is now published in Science Signaling! And it made the cover! @scisignal 🎉 Here’s what we found 🧵⬇️ https://t.co/ZaaN4bNfJb
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Leukocytes accumulate in the skin during psoriatic-like inflammation upon cleavage of surface heparan sulfate https://t.co/g5n7Pglq41
@scisignal @MegTriesScience @douglaspdyer 🇬🇧🇺🇸
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Pleased to now have the peer reviewed version of this study out in @MucosalImmunol
So pleased to share the first study from our @CRUK @MCRCnews RadNet collab led by the amazing @NabinaPun98 with @TravislabUoM and Prof. Illidge @UCytlak @CRGGlasgow @LydiaBeckerIII @wtccmr
https://t.co/kKrKo7wsCF
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So pleased to share the first study from our @CRUK @MCRCnews RadNet collab led by the amazing @NabinaPun98 with @TravislabUoM and Prof. Illidge @UCytlak @CRGGlasgow @LydiaBeckerIII @wtccmr
https://t.co/kKrKo7wsCF
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Not sure I'm the expert, but definitely we're all about the #ECMatrix (well, #CollagenI) with a dabble of #CircadianRhythms 😆
This month we are bringing the circadian rhythm in focus with a talk by @tranejoan on "(Circadian) control of collagen homeostasis – new paradigms and tools" Register now and don't miss a stimulating talk with all the latest updates from the expert herself https://t.co/qd0xs72HJS
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May is here, flowers are blooming and we have sooo much for u!!!! Go through our newsletter for a recap of our latest talk, hot off the press papers, career opportunities, spotlight interview with @Ekasit_Sp & upcoming events. All in one place!!! @ccstorytime @julieSdimartino
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*Tomorrow* we're joined by Dr Megan MacLeod from @UofGlasgow for our next @bsicongress MIG Seminar: “Different faces of immune memory” 📅 Thursday 13th March 🕐 12 pm 📍 Michael Smith Lecture Theatre
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Check out this educational resource, made by an undergraduate student at @OfficialUoM. Please support by watching their educational videos on how #malaria causes damage to the brain 🧠🦟 & share widely for as many responses as possible! https://t.co/GjIAXHsxbM
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🚨WE ARE HIRING!🚨 Lecturer in Neuroscience @FBMH_UoM More details and applications here > https://t.co/6CFR9VkWJt Please share! 🧠
jobs.manchester.ac.uk
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Lucky to work with some of the most amazing women in research!
Today is #InternationalWomensDay - the Becker is proud to be home to women conducting world-leading immunology and inflammation research. Watch this video for their advice to young girls and women pursuing a career in science + what today means to them. https://t.co/9Dh6GT3XJ1
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Please see below for some exciting lectureship vacancies in the division of Neuroscience at the University of Manchester. Come & join us in our great division.
🚨 WE ARE HIRING! 🚨 Come and join our dynamic team here in the Division of Neuroscience. Two positions available: Lecturer/Senior Lecturer posts are now live - all details here >
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