Thanks @yaojj02 and colleagues for hosting a fun visit to @DukeUBME! Awesome time with Junjie, @GerechtSharon, @SongLabDuke, @HosseinSalahsho, @chorye, @ZhiyangJin, Phil Romero et al.

Best group costume 2025! #JurassicLab 🦕🦖 🎃 Teamwork makes the scream work 👻

Some people might be offended But it’s actually sweet All the time you’ve spent on me It’s honestly wild All the effort you’ve put in It’s actually romantic 🎵

Tonight on @60Minutes: our Mice Against Ticks project. Led by @JoannaBuchthal w/@ixodesdammini, we asked communities how to edit wild mice to stop Lyme, b/c those who'll live with interventions deserve to shape them. We've engineered accordingly.

Years in the making — Mice Against Ticks is on @60Minutes this Sunday! Sneak peek: https://t.co/yzHdKmjSH2 Help stop Lyme! https://t.co/b6GBbq8zBv Heartfelt thanks to our amazing team, collaborators & island communities for bringing this story to life! #LymeDisease #MITMediaLab

:snaps: :snaps: :snaps: Just loved this, @erika_alden_d! We’re obsessed with better ways to track & share science. This ELN+LIMS built in Notion + Airtable is usable, readable, and full of real stats & insights. and it's pretty!

Amazing talk by @chorye about directed evolution, robotics and automation. Also very interesting links for education #SEED2025

A phenomenal interview with the scientist we owe multiple fields of science to. Thank you David for such phenomenal work and for communicating the importance of public funding with such clarity and purpose. Everyone should take 10 minutes to watch this.

I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with @WalterIsaacson & @amanpour on @AmanpourCoPBS, airing on @PBS tonight at 11 pm ET, and on @cnni earlier today. Pls share! https://t.co/cyVZpAwJiq

Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to @yuichi_furuhata, a true master bioengineer, on leading this excellent work!

The NIH notified me yesterday that there is currently no policy that supports applying for a R00 that is associated with a terminated K99. So now, both the postdoc K99 (Harvard, $250k) and the R00 (non-Harvard institution TBD, $750) are BOTH effectively terminated.

Our proposal supported lab automation software infrastructure, with backing from major robotics companies. It was due in a week. Pure idiocy. https://t.co/sQ1i50gLcQ

NIH just early-expired its 1st & only software NOFO: “Building Sustainable Software Tools for Open Science.” I guess “sustainable” is too risky now. So much for funding the STEM workforce.

Just checkin’ the till here, @BostonGlobe, but I think you missed a few thousand. Per my last count, @HarvardU has 13 affiliated hospitals, 2000+ PhD students and over 5000 postdocs.

Harvard notified me today that this K99 grant is terminated.

For anyone still not taking this seriously, this is what defcon 1 looks like re: the end of America as a scientific superpower. Heartbroken for our Harvard colleagues and for the world to lose these discoveries.

How are folks handling NIH’s no foreign subawards policy? Anyone working with consortia (e.g. Human @ProteinAtlas, Sweden), this is a big issue—some orgs are the only source for rare reagents/proteins, sold at cost. Curious what implications this has + how ppl plan to navigate.

Last week, I had the pleasure of visiting the @DukeU Center for Biomolecular and Tissue Engineering to discuss our latest work using AI to accelerate antibiotic discovery. Thank you @pranamanam, @chorye, @SophieVincoff, and more!

Counterpoint: Physics-derived modeling has dramatically improved clinical trial success rates and efficiency. QSP is one of the most sought after skill sets and highest paying job tracks in pharma right now.

Read: OpenAI raised $40B in one round—i.e., the entire NIH budget.