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Christopher Bohrer Profile
Christopher Bohrer

@cbohrer3141

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Postdoc at NIH/NCI, Ph.D. @Hopkins

Joined January 2013
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@cbohrer3141
Christopher Bohrer
1 year
I've always been obsessed with how genes and enhancers talk to each other. Our latest review explores just that. Enhancers: A Focus on Synthetic Biology and Correlated Gene Expression | ACS Synthetic Biology .
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pubs.acs.org
Enhancers are central for the regulation of metazoan transcription but have proven difficult to study, primarily due to a myriad of interdependent variables shaping their activity. Consequently,...
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@cbohrer3141
Christopher Bohrer
2 days
RT @Eric_Betzig: Apoptotic vesicle release from a cell as it gives up the ghost under oxidative stress, as seen by MOSAIC lattice light she….
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@grok
Grok
4 days
Join millions who have switched to Grok.
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@cbohrer3141
Christopher Bohrer
4 days
RT @MariosGeorgakis: 17,186 genes were differentially expressed between biopsy-derived brain tissue from 275 living patients and 243 postmo….
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@cbohrer3141
Christopher Bohrer
4 days
RT @NikoMcCarty: A single E. coli cell, placed on a dish, will become 70 billion cells in just 12 hours. That’s exponential growth. But a….
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@cbohrer3141
Christopher Bohrer
6 days
RT @MuzumdarLab: 💡 Cancer cells don’t just mutate—they reorganize their DNA in 3D space. Our new study shows how the genome’s folding patte….
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@cbohrer3141
Christopher Bohrer
11 days
RT @rooij_laura: 🚨Preprint alert!🚨What happens to our blood vessels as we age? To begin answering this at the transcriptome level, we built….
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biorxiv.org
Endothelial cells (ECs) are critical regulators of vascular function and exhibit specialized, organ-specific roles across tissues. During aging, these cells become dysfunctional, resulting in...
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@cbohrer3141
Christopher Bohrer
11 days
RT @xashleefeng: A brief summary/perspective on my recently published PhD work: Nucleosomes constrain 1D DNA diffusion by eukaryotic transc….
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nature.com
Nature Structural & Molecular Biology - The transcription factor GAGA factor (GAF) recruits chromatin remodelers to establish and maintain open chromatin for transcription in Drosophila...
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@cbohrer3141
Christopher Bohrer
12 days
RT @SStevenWang: Glad to share our latest publication in Nature Genetics @NatureGenet: Tracing the evolution of single-cell 3D genomes in K….
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@cbohrer3141
Christopher Bohrer
14 days
RT @xielablife: Happy to share our work on how chromatin organization is established for the first time in early mouse embryos, in part via….
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nature.com
Nature - A study reveals progressive cohesin loading and a hypertranscription state responsible for the formation of genic cohesin islands at active regulatory genes in mouse embryos, highlighting...
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@cbohrer3141
Christopher Bohrer
17 days
RT @ericjoycelab: 🚨New preprint from the lab🚨.🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide….
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biorxiv.org
The nuclear periphery is a key site for heterochromatin organization in eukaryotic cells, where lamina-associated domains (LADs) promote transcriptional repression and genome stability. Despite their...
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@cbohrer3141
Christopher Bohrer
1 month
RT @eLife: A simple flow of gas over water may have helped kickstart life on early Earth. Research shows how evaporation and fluid flow in….
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@cbohrer3141
Christopher Bohrer
1 month
RT @PRX_Life: In our first review, scientists revisit how physical forces shape collective #AnimalBehavior, revealing how individual-enviro….
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@cbohrer3141
Christopher Bohrer
1 month
RT @slavov_n: How challenging is the prediction of transcriptional responses to CRISPR gene perturbations ? . A simple model, just scaling….
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@cbohrer3141
Christopher Bohrer
1 month
RT @taekjip: A conserved coupling of transcriptional ON and OFF periods underlies bursting dynamics | Nature Structural & Molecular Biology….
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nature.com
Nature Structural & Molecular Biology - Gene activity levels predict how often and how strongly genes turn on and off. Using live imaging in fruit fly embryos, the authors uncover a conserved...
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@cbohrer3141
Christopher Bohrer
1 month
RT @luigiadamomdphd: Analyzing human myocarditis at the tissue transcriptomics levels, with two different platforms, we found that the dise….
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biorxiv.org
Background Myocarditis is an inflammatory disease of the myocardium, classically defined and graded by histologic criteria that emphasize immune infiltrates and focal cardiomyocyte injury. The...
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@cbohrer3141
Christopher Bohrer
2 months
RT @arjunrajlab: Very excited to share our new work on gastruloids by the incredible @ugcgccacc! We mapped gene expression across 26 indivi….
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@cbohrer3141
Christopher Bohrer
2 months
RT @FukayaLab: Delighted to share a new review paper from the lab. We discussed recent key findings in enhancer biology. Thanks Dan Larson….
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