Xinyu Feng
@xashleefeng
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Postdoc @ Lacra Bintu Lab
Stanford, CA
Joined March 2020
A brief summary/perspective on my recently published PhD work: Nucleosomes constrain 1D DNA diffusion by eukaryotic transcription factors https://t.co/VnpaEu0gbc
@taekjip
nature.com
Nature Structural & Molecular Biology - The transcription factor GAGA factor (GAF) recruits chromatin remodelers to establish and maintain open chromatin for transcription in Drosophila...
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My PhD work is online! Huge thanks to my advisors Carl and TJ, and collaborators! @taekjip @maryamyamadi @FuYiben @Mejohnson81
GAGA zinc finger transcription factor searches chromatin by 1D–3D facilitated diffusion https://t.co/LbRmYoghXG
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"Native nucleosomes know where to go!” Our Condense-seq paper is now published in Nature! 📄 https://t.co/hNWY0rxsnk I’m deeply grateful to my PhD advisor @taekjip and our incredible collaborators @MuirLab , @binzmit , Erika Pearce, and Ben Garcia lab!!
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The DelRosso Lab is starting @UCSF 1/2025 and is seeking applicants for a research postbac! We will be developing cutting edge high-throughput approaches to study the relationship between disordered protein interactions and transcription in human cells🔎 https://t.co/C1bO6omasm
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We are hiring a lab manager/research assistant. Hoping to interview and choose one over the next few weeks. Please apply through the Stanford posting https://t.co/VoBwZdtFaz or email lbintu@stanford.edu with CV, transcript, career goals, and desired start date.
careersearch.stanford.edu
located in Shriram Center, is seeking a Life Science Research Professional to join our team as lab manager and research assistant. Responsibilities...
We are hiring a lab manager/research assistant! More details and how to apply here:
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Proud to announce my latest preprint, the culmination of my dissertation research defended two weeks ago! As co-first author, I'm excited to share the "dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers". https://t.co/EkMjg7qGgF
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Check out this cool video made by @janetiwasa! The DNA and histone dynamics in the animation was based on our recently published paper with @MPoyton @taekjip and Carl Wu et al.
science.org
Multicolor single-molecule FRET reveals how SWR1 unwraps DNA to exchange nucleosomal H2A-H2B for H2A.Z-H2B.
Just wrapped up a fun project visualizing histone exchange by SWR1 with the labs of Carl Wu and @taekjip. We created a short narrated animation (linked below) and a longer one that directly used FRET measurements in the animation (check that one out here: https://t.co/NqRs4QZxTq)
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COSB has a special issue on Biophysical Methods "Seeing is Believing". Free to read for three months. https://t.co/EhiOaskHic
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Want to know how long it takes SWR1 to remodel a #nucleosome? @xashleefeng and I used #smfret to watch SWR1 in action! Big-ups to everyone in Carl Wu’s and @taekjip’s labs for making this happen.
Coordinated DNA and Histone Dynamics Drive Accurate Histone H2A.Z Exchange https://t.co/PyVoGxcca2
#bioRxiv
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We posted two manuscripts on small RNA-based gene regulation in bacteria. Quantitative super-resolution imaging and stochastic modeling. Wonderful collaboration with Cari Vanderpool and Zan Luthey-Schulten labs. https://t.co/RSGaq5xsg0
https://t.co/2T2I2ODb4a
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Delighted to share my work @JohnsHopkins on ‘Very fast #CRISPR’ @ScienceMagazine ! Could not have done this without my fantastic advisors @taekjip @Binwulab, amazing colleagues @rogerszou, Shuaixin, Yuta, Xiaoguang, @sh_razavi and everyone contributed! https://t.co/kEsNOZqUo0
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Check out this new @elife paper from Carl Wu’s lab. They used live-cell single molecule imaging to show how RNA Pol II kicks H2A.Z out of promoters.
elifesciences.org
Histone variant H2A.Z is deposited near transcription start sites by the chromatin remodeler SWR1 and seems to be removed by RNA polymerase II at an early stage of transcription elongation.
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