CannaLab
@canna_lab
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Auto- & Hyper-inflammation | MAS HLH | IL-18 | Down wit OPD | ❤️er of puns (see logo) | 🚲 evangelist | opinions my own
Philadelphia, PA
Joined October 2018
"Modeling the HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death" #HLH travels under many names (#MAS, #CRS, ...), all united by T-cell hyperactivation. https://t.co/F1aJAumXdE
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~30 min each way x 5+ days/week x ~48 weeks. Recharges: 5-6 Dead battery: 1 - I got lazy Casualties: 0 (unless you count all that gnar I shredded) stay bright, y'all
About 🚴 commuting: it gets dark early now. Helmets are great, but much better to avoid being hit. Enter @redshift_sports & https://t.co/X4S6KVtnie Not cheap, but v smart (auto on/off, red/white) & solid. Surprisingly long 🔋. My bike is a festival of lights!
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HLH, Trisomy 21, immune dysregulation ... Case conf webinar featuring: Joaquin https://t.co/cO3o0bdkJR Thursday 13 November, 11AM ET Register at https://t.co/k3zgpJ0hmd
#CIS, @HistiocyteSoc, @Histiocytosis
us02web.zoom.us
Welcome! You are invited to join a webinar: Joint CIS & Histiocyte Webinar. After registering, you will receive a confirmation email about joining the webinar.
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Lab successfully escaped escape room. Teamwork: easy. 3x3 slide puzzle - apparently very difficult.
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We have Allergy positions open at CHOP. We are looking for people to join a dynamic group with a strong tradition in food allergy and a growing food challenge and oral immunotherapy program. Reach out to Kate Sullivan.
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I'm sorry to have missed this, but so grateful for all that folks like Karen @AAlliance_SAID and the teams @PeriodicFeverUK, @CdnANetwork, @IndiaSAIDgenome, @autoinflamaware, @RACC_UK do for patients with #autoinflammatory diseases. Big things for this community in 2026!
Come to Methuen Riverwalk, MA @ 7 pm for a night of fun to Shine 4 Sammy & Int'l #Autoinflammatory Awareness Month! The falls will be lit orange! 🧡 https://t.co/sRjJaGfavP
#autoinflammatory #shine4autoinflammatory #OrangeEra #august4autoinflammatory #autoinflammatoryawareness
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ISGs: bet you can't have just one!
Latest from us. Universal antiviral made! How? Transient gene therapy. Which genes? Only 10 suffice, out of thousands of antiviral host genes. How did we choose? Got inspired by patients and gene promoters. Read in detail 👇🏼
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Why test #celltherapies one-by-one when you can use multiplexed #SynBio, #proteinengineering & #ML to design, measure & track them at scale? The Goodman Lab @PennMedicine opens July 2025. We’re hiring Specialists & Postdocs! Apply @ https://t.co/DE7aPLp9vr RTs appreciated!🙏
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Too bad that the timelapse we made of an activated CTL (green, Ca++ flux) and contracting BMDC (red/PI) was too low-res for the cover.
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Thx @BloodPortfolio editors for highlighting our work (led by @AFKamenetskii) on the HLH Immune Synapse https://t.co/F1aJAumXdE Thx to the editors and to @MachowiczRafal & @paul_la_rosee for their editorial "HLH: it is all about communication" https://t.co/kHpnGBAzRW
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T cells do the heavy lifting when it comes to the anti-tumor action of checkpoint immunotherapy. But do antibodies play a role too? That’s the question @yile_dai looked to answer in his thesis work, out today in @Nature! 🧵below https://t.co/VgTByRKRCX
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"Multi-Disciplinary Approach to Managing #HLH" Register at
us02web.zoom.us
Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom...
Join us for a webinar: Multi-Disciplinary Approach to Managing HLH with Drs. Jessica Manson & Rachel Tattersall, who have led a UK-wide effort to bring excellent HLH care to their institutions and the broader NHS and to track the outcomes of their interventions. @canna_lab
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thx @LabWaggoner, beat us to it!
Preprint: Multimodal induction of fulminant HLH by IL-18 includes virus-specific NK immunodeficiency @canna_lab @varghese_jemy
https://t.co/UkYpjpl8lw
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Honored by shout-out from the legendary Dr. De Benedetti at #EULAR25 Check out @AFKamenetskii 's paper. @BloodPortfolio
https://t.co/F1aJAumXdE
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Fun writing "Insights from the 2024 ACR/PRES Peds Basic/Translational YIR" with the talented Dr. Jessica Turnier @umichmedicine. Thx for invite @ChristophKessel and PROJ. 1st time citing @DGlaucomflecken ... so far. https://t.co/92nd45JG2e
link.springer.com
Background Advances in Pediatric Rheumatology are driven by mechanistic insights from basic and translational science. We have selected and reviewed the most impactful basic/translational science...
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Drs. Manson & Tattersall have led a UK-wide effort to bring consistent, excellent #HLH care to their institutions & the broader @NHSuk ... & tracking their outcomes. Please register:
us02web.zoom.us
Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom...
@HistiocyteSoc #HLH Webinar "Multi-disciplinary Approach to Managing HLH" Headlined by @JessicaJManson & @R_tattersall (@ucl) who've really brought HLH excellences to @NHSuk July 24th, 11AM NY/8AM SF/4PM UK/5PM CET Details and link are forthcoming
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Piloted by @AFKamenetskii & crew (@varghese_jemy, @JeremyMx96, @JoeFraietta, @CarolineDiorio, ...) this project grew from foundational work out of Melbourne, 🇦🇺 by @DrMistyJenkins, JTrapani, & IVoskoboinik.
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The gut-wrenching irony of so many libs voicing their outrage ... by donating content to X.
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Welcome to Philly, where it's always sunny. Additionally, I'm dropping my worst puns over where the grass is greener on the posting site where the sky is bluer.
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