Cameron McAlpine
@cam_phd
Followers
2K
Following
2K
Media
36
Statuses
573
Brain-body circuits in sleep, heart, and brain disorders @IcahnMountSinai @SinaiHeartBlood @SinaiBrain @SinaiImmunol
New York City
Joined December 2017
It was a pleasure to speak at the ITMAT symposium at U Penn, a truly translational and multidisciplinary meeting!
#Sleep & #Immunology & #MyocardialInfarct by @cam_phd at #ITMATSymposium #ITMAT2025 #TranslationalScience
0
2
9
For anyone who has wanted a clear, authoritative summary of inflammation and cardiovascular disease, and where the science is heading, here it is. The 2025 ACC Scientific Statement on Inflammation and Cardiovascular Disease. @JACCJournals
jacc.org
0
21
60
It was an amazing day of systems cardiovascular science!
An absolutely fantastic 4th annual @SinaiHeartBlood retreat delving into connections between heart, brain, liver, kidney and all the myriad ways systems connect. Our community is strong and growing — See you next year!
0
4
19
PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the
32
175
939
Why do we sleep? And how? The 2 theories, broken down https://t.co/NfVw6XFbXE
@NeuroCellPress
9
308
1K
Proud to help launch NY-CURES advocating for sustained investment in NY science. Investing in NY science helps discover new cures, create jobs, and build a healthier future. I encourage everyone to learn more and join us:
2
17
89
Connecting, sharing feedback, and finding collaborators are at the heart of Cell Symposia poster sessions—especially in the beautiful, historic setting of the New York Academy of Medicine. #CSNeuroimmune25 @ImmunityCP @NeuroCellPress
1
6
18
We are thrilled to share our latest work now published in @CellReports! We combined #scRNAseq and #MERFISH on mouse models of type 2 skin inflammation to uncover a critical basophil-fibroblast crosstalk axis in amplifying inflammation. A thread 🧵 1/11
A basophil-fibroblast pro-inflammatory axis fuels type 2 skin inflammation
3
8
37
Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia | Science
science.org
Ventricular tachycardia disrupts the heart’s coordinated pump function, leading to sudden cardiac death. Neutrophils, which are recruited in high numbers to the ischemic myocardium, promote these...
1
26
60
It was a pleasure to present data from the lab at #ESCCongress! There has been a great focus on neuronal and immune contributions to CVD.
Why do damaged hearts require more sleep? Cameron McAlpine explores the increased need for sleep post-#MI including mechanistic insights & results from animal & human studies #ESCCongress #HeartAttack #CVD #inflammation #CardiovascularResearch
3
3
40
Discover more on heart-brain axis interactions in #CVD in our recent #CardiovascularResearch Spotlight Issue on the brain, heart, and vessels crosstalk composed by Guest Editors Daniela Carnevale, Costantino Iadecola & Joanna Wardlaw https://t.co/uzQ5CcR5dG
#ESCCongress
1
7
18
Major congrats to @mchonig with THREE simultaneous senior-author publications during #ESCCongress25 each with a different first-author from his group! 👏 1️⃣ https://t.co/QNE0mRPIEJ
@JACCJournals 2️⃣ https://t.co/lL4U3LogL6
@JACCJournals 3️⃣ https://t.co/oNKAAftAwl
@JAMACardio
jamanetwork.com
This study tests whether clonal hematopoiesis of indeterminate potential is associated with the development of myocarditis and pericarditis.
3
15
83
In this exploratory analysis, Tx w/ low-dose colchicine was assoc w/ an attenuated annual clonal growth in TET2 CH. Findings suggest potential for colchicine to curb proliferative advantage of key CH driver mutations https://t.co/QipRX2Dn6U
#ESCCongress #WCCardio #JACC @mchonig
0
6
28
Join @cam_phd at #ESCCongress 2025 with #WCCardio for his presentation on "Damaged Hearts Require More Sleep" on Sunday, August 31. #CardioX @escardio @IcahnMountSinai
0
3
13
New concept & changes to peer review to make it faster and more friendly: 👇 Unleashing the Power of the Beehive to Begin a New Era for JACC: Basic to Translational Science https://t.co/Mo1MgT0S3M This only works if you, our readers, authors and referees, embrace it!!
jacc.org
2
12
31
Fantastic HFpEF review from experts in the field out in JACC: Basic to Translational Science 🫀❤️🔥
jacc.org
2
7
25
✨HUGE CONGRATULATIONS to @IcahnMountSinai's Dr. Cameron McAlpine @cam_phd on being honored w/ the Dr. Harold & Golden Lamport Basic Research Award for demonstrating exceptional promise for making significant, long-term contributions to biomedical research!🎉👏
1
8
33
I am honored to receive this award! It is a testament to the lab and their hard work!
7
5
47
This was so much fun to write, thank you @SwirskiLab and @FGinhoux !! A summary of the many surprising jobs that immune cells do after hours (and it is more than just cleaning up) Immune system influence on physiology | Science
science.org
The immune system’s central function is to maintain homeostasis by guarding the organism against dangerous external and internal stressors. Immunity’s operational toolbox contains diverse processes,...
7
62
225