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Paul Brennan Profile
Paul Brennan

@brennap9

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Hepatology Clinician Scientist, Edinburgh/Dundee Trainee Rep @SSG and @BASL Often to be found watching rugby 🏉

Scotland, United Kingdom
Joined September 2013
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@brennap9
Paul Brennan
9 months
Very excited to present our phase 2 RCT on “ autologous macrophage therapy for liver cirrhosis” published today in @NatureMedicine https://t.co/uetgfK8i8p ⚡️I've summarised some of the key aspects of the trial 🧵
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nature.com
Nature Medicine - Results from the phase 2 MATCH01 clinical trial of autologous monocyte-derived macrophage therapy for liver cirrhosis revealed no liver-related severe adverse events or deaths in...
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@LiverAHPs
LiverAHPs
4 days
Brilliant expert panel discussed hosted by Prof. Matt Armstrong and Prof. Suzanne Norris .. a vibrant discussion emphasising the importance of an MDT approach with emphasis on AHP involvement and lifestyle intervention @Drfattyliver @BASLedu #BASL2025
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@druppygill
Uppy Gill
5 days
Superb lecture by @brennap9 for the prestigious #SheilaSherlock award… Adding to the illustrious winners - @Drwenhaoli @KushAbey @prakramacha @FSampaziotis @Drfattyliver & many other legends….
@OTavabie
Oliver Tavabie
5 days
A very worthy Sheila Sherlock winner - congratulations ⁦@brennap9#basl2025@BASLedu⁩ ⁦@JVLazarus⁩ ⁦@aelsharkawy75⁩ ⁦@Drwenhaoli⁩ ⁦@druppygill⁩ ⁦@tom_marjot⁩ ⁦@DebbieShawcros1⁩ ⁦@stumcp⁩ ⁦@BritSocGastro
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@Drwenhaoli
Wenhao Li
5 days
Huge body of work! Big fan 🤩 congratulations @brennap9 👍
@OTavabie
Oliver Tavabie
5 days
A very worthy Sheila Sherlock winner - congratulations ⁦@brennap9#basl2025@BASLedu⁩ ⁦@JVLazarus⁩ ⁦@aelsharkawy75⁩ ⁦@Drwenhaoli⁩ ⁦@druppygill⁩ ⁦@tom_marjot⁩ ⁦@DebbieShawcros1⁩ ⁦@stumcp⁩ ⁦@BritSocGastro
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@OTavabie
Oliver Tavabie
5 days
A very worthy Sheila Sherlock winner - congratulations ⁦@brennap9#basl2025@BASLedu⁩ ⁦@JVLazarus⁩ ⁦@aelsharkawy75⁩ ⁦@Drwenhaoli⁩ ⁦@druppygill⁩ ⁦@tom_marjot⁩ ⁦@DebbieShawcros1⁩ ⁦@stumcp⁩ ⁦@BritSocGastro
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@Mister_trip
Jose MA
5 days
@OTavabie @brennap9 @BASLedu @JVLazarus @aelsharkawy75 @Drwenhaoli @druppygill @tom_marjot @DebbieShawcros1 @stumcp @BritSocGastro Well deserved indeed! Excellent researcher and colleague. They are lucky to have him!
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@OTavabie
Oliver Tavabie
12 days
This is a MUST read - lots of practical tips and insights relevant to anyone managing patients with liver disease @BASLedu @BSGTrainees @BavenoCoop @EASLedu @AASLDtweets @WAGE_media @ScotSocGastro @ulstergastro @LiverTrust
@FrontGastro_BMJ
Frontline Gastro
12 days
🚨💥 BIG NEWS 💥🚨 The FIRST-EVER FG × BASL Special Issue has LANDED! 📚 14 hepatology must-reads 🔓 OPEN ACCESS (but only for a short time ⏳) 👉 https://t.co/NI1pHJsobF #FGBASLSpecialIssue #LiverTwitter @basl_events @heppharm @livernursing @LiverAHPs @Liver4Lifeuk
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@NeilRajJ1
Neil Rajoriya
16 days
Superb surgical team (& not bad medical colleagues 😉). And most importantly a great chance to help our liver patients awaiting a life saving liver transplant
@Drfattyliver
Matthew Armstrong 💙
16 days
@uhbtrust⁩ ⁦@basl_events⁩ ⁦@BTStransplant⁩ ⁦@EASLnews⁩ liver transplant consultant retrieval job with scope to deliver NRP. Short application time ⁦@NeilRajJ1⁩ ⁦@jfergus75
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@tom_marjot
Tom Marjot
17 days
This was a really enjoyable #MASLD meeting with @basl_events It's always great to have basic science, translational research, and clinical updates placed side-by-side 🙏Thanks to @AHadjihambi @TessCacciottolo @JAFallowfield @brennap9 @WillAlazawi @barbarat1966 @leannehodgson4
@basl_events
BASL
25 days
Thanks to everybody who visited Oxford for the first #MASLD Symposium from @basl_events 🔹60 delegates 🔹Representation from England, Ireland, Scotland, & Wales 🔹10 expert speakers 🔹5 industry partners 🔹Lots of discussion + new collaborations Join the SIG:✉️sigs@basl.org.uk
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@OTavabie
Oliver Tavabie
20 days
Amazing stuff - moving to prospectively collected data demonstrates the evolution of @uk_torch - good luck with this project which is patient-centric and an area of need! An RCT for the next one maybe @RajivJalan1 @BASLedu @BritSocGastro @UK_CLIF @BSGTrainees
@uk_torch
ToRcH-UK
20 days
We are officially live! #EVADE is running and we are encouraging sites to sign up! But what is EVADE and why should you even be interested in signing up? (1)
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@FrontGastro_BMJ
Frontline Gastro
24 days
📢 Just announced! The next BSG/FG webinar "Decompensated Cirrhosis – Bundles and Beyond" is happening on 🗓️ 1st October ⏰ 19:00–20:00 BST Join hepatology heavyweights @ebtapper, @salvatore_piano & @stumcp for what promises to be a top-tier session, hosted by 🎙️ @KGananandan,
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@uk_torch
ToRcH-UK
25 days
📢 We are about to GO LIVE with our next project EVADE 📢 Evaluation of the Variation in Management and Outcomes after an Acute Decompensation of Liver cirrhosis Event From speaking to patients we know this is an area of unmet need! #livertwitter 🦋 https://t.co/HbRTEhmZlk
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@OTavabie
Oliver Tavabie
27 days
Delighted to share our work on behalf of @BritSocGastro Quality Standards group in collaboration with the @LiverTrust 'Development and feasibility of a patient-reported experience survey for outpatients with liver disease' in @FrontGastro_BMJ https://t.co/otZLTp9ta0
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@touchENDOCRINE
touchENDOCRINOLOGY
1 month
🩺 Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive liver disease linked to obesity, diabetes, and metabolic syndrome. In this practical Q&A, Dr Paul Brennan @brennap9 shares how to: 🔹Recognize key risk factors 🔹Use non-invasive tools for early
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@FrontGastro_BMJ
Frontline Gastro
1 month
🚨 Big news! We're thrilled to announce that Frontline Gastroenterology @FrontGastro_BMJ is now the official journal partner of the Roux Group @roux_group – the trainee arm of AUGIS @AUGISnews! Editor-in-Chief Dr Philip Smith @PhilSmithIsBack: “Surgeons are key to the MDT in GI,
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@DebbieShawcros1
Debbie Shawcross
1 month
https://t.co/y8IPMV2ODB 📣📣📣 Calling all @BSGTrainees @BSGNurses @BASLedu #GITwitter #livertwitter Registration is now open for the BSG Introduction to Research Day for Trainees & Nurses 29th Nov 2025 Radisson Hotel York Register now! @OTavabie @tom_marjot @RCPhysicians
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@IrishLiverNurse
Irish Hepatology Nurses Association (IHNA)
2 months
Such an important initiative 👏🏻 Liver disease is silent until advanced stages when symptoms start to show. Screening allows for early detection and intervention, aiming to prevent cirrhosis and liver cancer 💚 @HSELive @IrishHaemAssoc @PBCIreland @AlcoholIreland
@IrelandLiver
Irishliverfoundation
2 months
We are delighted to announce that we are providing free liver health screens across Ireland, starting this Saturday in Dublin! In collaboration with LISN patient group @LiverTrust @EASLnews @Independent_ie @IrishTimes @rtenews @IrishLiverNurse @LiverBeaumont
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@brennap9
Paul Brennan
2 months
@DrLoomba @AlkhouriNaim @TheLancet @JVLazarus @Drfattyliver @EASLnews @JAFallowfield @ProfJohnDillon @dundeeuni @OTavabie @LancetGastroHep @BASLedu @UCSDHealth Read the full paper here; the future of advanced liver-directed therapies is getting ever closer. https://t.co/89Aj3nvKTs More treatments offer better outcomes for patients, particularly as we begin to understand differences in phenotypes and outcomes in patients with MASLD.
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@brennap9
Paul Brennan
2 months
Our commentary of the very novel anti-sense oligonucleotide trial in MASH by @DrLoomba and @AlkhouriNaim in @TheLancet https://t.co/7RqZxvDANx Another future tool? Let's hope so, the field is moving at pace on the back of EMEA approval of #rezdiffa and FDA of #Sema
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@Drfattyliver
Matthew Armstrong 💙
2 months
Amazing achievement @novonordisk @phil_newsome7 @unibirmingham @BirminghamBRC @uhbtrust 16 years! on from the start of our phase 2 LEAN (liraglutide) RCT @TheLancet. Drug development is difficult in #NASH, even when GLPs were approved for other conditions it’s taken this long
@DrLoomba
Rohit Loomba
2 months
Novo Nordisk's Wegovy gets accelerated US approval for liver disease MASH
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@Dr_Ampuero
Javier Ampuero
2 months
🔝🔝🔝 FDA grants accelerated approval to Wegovy (semaglutide 2.4 mg injection) for treating adults with non‑cirrhotic metabolic dysfunction‑associated steatohepatitis (MASH) with moderate to advanced fibrosis (but not with cirrhosis). https://t.co/nRzDIR82C3
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