Patty Pringle Bloom, M.D.
@BloomPringle
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Transplant Hepatologist @mayoclinic | Alum of @MGHMedicine and @MGH_GI | Hepatic encephalopathy, microbiome | AE @HepCommJournal | Tweets are my own
Rochester, MN
Joined November 2018
Last year, @NIDDKgov sponsored a symposium on gut microbiota and kidney disease Here is the product of a huge team effort: A Roadmap of our current understanding, and recs for future research in this space https://t.co/KKZYCbB22d
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Last week I began the next step in this journey, at the Mayo Clinic🥳 Absolutely thrilled to be here, and eager to get to work
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I’m back! Took a break for mat leave 👩🍼 More big news! After 5 wonderful years at UMichigan, I have packed up my lab (and family) It is hard to summarize how incredible Michigan was for my career and life. I owe my UM colleagues and friends everything ❤️
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How reversible is hepatic encephalopathy after all In some cases, the damage persists Important paper: https://t.co/qIG4SfgE62 Hey, @serperm, maybe we should work on preventing HE?
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This trial by @BloomPringle will be seen as one of the most important in the field of FMT - 💩 transplant - for #cirrhosis Does the 💩 engraft? Does the 💩 work (improved barrier function)? This is why P P B is the future https://t.co/LsX8fW724U
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Gut R. gnavus may induce monoamine synthesis and neurotoxicity in some patients with #cirrhosis, causing #hepaticencephalopathy — revealing a possible therapeutic target for this understudied condition. News & Views from @BloomPringle @MichiganLiver
https://t.co/cvAYYv4Qub
nature.com
Nature Medicine - New evidence suggests that Ruminococcus gnavus in the gut induces monoamine synthesis and neurotoxicity in some patients with cirrhosis, causing hepatic encephalopathy —...
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In #CTGjournal: The Misdiagnosis and Underdiagnosis of Hepatic Encephalopathy Patricia Bloom, MD ➡️ https://t.co/nzu5V0Rd7B
@BloomPringle @AmCollegeGastro @brianjacobsonmd @YhernandezMD @LevinthalDavid @EugeniaShmidtMD @singal_ashwani
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In pts w #hepaticencephalopathy on max Rx..how can we⬇️recurrence? #gutbrainaxis In our #FMT Phase 2 trial @JHepatology funded by @VAResearch 🔑FMT capsule💊/💉enema➡️safe 🔑 FMT doses (1-2-3) >>placebo ⬇️HE recurrence 🔑 Donor engraftment matters!⤵️ https://t.co/6glUnREzxu
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Fibrates and other PPAR agonists are so hot right now 🔥🔥🔥 Here is a review of how they work, the evidence of benefit, and the bright future of this pathway in improving liver health https://t.co/3hJQa0Yu8q
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📑 Validation of #MELD3.0 in 2 centers from different continents 🌎 In this study, MELD 3.0: 🔹Had highest mortality prediction in women 🔹But not superior to MELD-Na https://t.co/JogzChpNTB
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Flying home from @AASLDtweets and @EASLnews Masterclass full of new inspiration and with many new friends 😊 So thankful that these two organizations prioritize young investigators as much as they do
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Family photo @EASLedu @AASLDtweets MASTERCLASS Wonderful group
@EASLnews @AASLDtweets MASTERCLASS in beautiful Savannah ❤️ Gathering of next generation of leaders in hepatology🤩🤩 👉team science 👉building a team Networking among liver friends @FrancqueSven
@EASLedu
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@EASLnews @AASLDtweets MASTERCLASS in beautiful Savannah ❤️ Gathering of next generation of leaders in hepatology🤩🤩 👉team science 👉building a team Networking among liver friends @FrancqueSven
@EASLedu
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I am VERY impressed by the work of @JessBRubin on pain in cirrhosis #TLM2024 Since opioid safety initiatives, opioid prescribing is lower in cirrhosis and acetaminophen, NSAIDs, & gabapentin scripts are UP Now, how has that affected pain control for our patients? More to do…
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PROUD of @UMich medical student Gabe Rice for presenting our work on EEG as a way to optimize anesthesia management in liver transplant @AASLDtweets He has learned so much from this project. It’s been incredible to see his growth and the final product #mentorPROUD
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Dr @ponnivp Perumalswami delivering a masterclass on alcohol related liver disease We are hepatologists, but we CAN and SHOULD be prescribing medication to treat alcohol use disorder Naltrexone, NNT = 7! Hard to beat.
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You may leave the institution where you trained (❤️ you @MGH_GI), but if you’re lucky, those mentors never leave YOU Thanks @raychungmd and @JHEP_Reports for inviting us to write our thoughts on the FUTURE of microbiome therapeutic trials in cirrhosis https://t.co/OUeQgriudw
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Another engaging liver transplant journal club with the UMich transplant team! Talking about PTLD Rare, so literature is limited. Hard to know what to do 🤔 Decrease Tac? Switch to mtor inhibitor? Are we immunosuppressing too much in the first 6 months?
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Original Article HEAR-MHE study: Automated speech analysis identifies minimal hepatic encephalopathy and may predict future overt hepatic encephalopathy Bloom et al. #LiverX
https://t.co/QXpQ8wYS6x
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Thank you to our funders! @AmerGastroAssn and the Michigan ADVANCE award Link to article: https://t.co/MytvzPzX38
journals.lww.com
m (1) correlates with validated HE tests, (2) correlates with MHE, and (3) predicts future OHE. Approach and Results: In a two-center prospective cohort study of 200 outpatients with cirrhosis and 50...
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