Extremely proud to present my new paper https://t.co/IlTizJ5Iy9 done in collaboration with the amazing Ruben Casanova @uria_mor. 1/4

Happy to announce #SCG2023! For the first time in the Swiss Alps! Exciting speakers! Website is up! Save-the-date: Registration opens May 2nd. https://t.co/2A2iwuHtbR @IdoAmitLab, AmosTanay, @slinnarsson, @sandberglab, @AlexandervanOu1, @MarioniLab AvivRegev @genentech, @ETH_en

I'm very excited to share that our work is online @Nature! We found that STING suppresses progression of dormant metastasis. Huge thanks to all the co-authors! @LabMassague @LoweLabMSKCC @SunLab_Official @dana_peer @KarunaMDPhD @ciacobu @MSKCancerCenter https://t.co/fjgM08FPnA

These methods are implemented with our new package R Balagan available on Github https://t.co/yCptfiM5KE !

Second: instead of randomly selecting the regions of a sample to image (random sampling) we propose to apply an other sampling strategy called stratified sampling that is extensively used to improve surveys. 4/4

We propose two strategies to overcome this limitation : first the use of an appropriate statistical model and statistical test (beta-binomial regression model) that boosts the statistical power of differential abundance analysis 3/4

This paper addresses the main limitation of multiplexed imaging identified by recent works including the landmark paper of the Sorger lab https://t.co/BNpxCSWtUz, i.e the low statistical power of small-TMA based studies 2/4

Submitted to eLife

My 2 cents about @eLife criticisms of gatekeeping: phrased differently, that's curation. This is exactly what I expect editors to do because it's impossible to read all preprints and we need a trusted curation system.

As a mathematician, I am deeply offended when people say "Don't put math on the slides" even for talks meant for tech or Science students. It's like Maths is something ugly or scary or maybe we should put a "trigger warning" for Maths!

Spatial epigenome–transcriptome co-sequencing🤩🤩🤩Beyond excited to see it out today @Nature! Enjoyable collaboration between my lab @YaleBME @YaleSEAS @YaleMed and @GoCasteloBranco of @karolinskainst. The most informative tool for spatial multi-omics!! https://t.co/hRTtfGVbno

En ces temps de bullshit spreading global, il est temps de ressortir les 10 commandements d'Arthur Kornberg. C'est de l'enzymo, mais ça s'applique à tout. Mon préféré: "Don't waste clean thinking on dirty enzymes" (on pourrait dire: "on dirty science") 😉 https://t.co/MbfMFLcVTN

If you want to do science at the intersection of virology and systems biology, you should apply to our open post-doc search. We offer an amazing environment, both physical and scientific, and great compensation. To learn more please e-mail me with your CV and cover letter.

Droplet-based forward genetic screening of astrocyte–microglia cross-talk. Congrats to @mwheeler0 and @QuintanaLabHMS on the groundbreaking work. For those looking for a postdoc, check @mwheeler0 out, he is going to be a fantastic PI.

When an already independent PI publishes together with his post doc advisor

When the reviewer asks you to cite their irrelevant paper

Post docs applying for PI positions https://t.co/jAZU8kpK6l

Really proud to see my recent work highlighted by @naturemethods : https://t.co/kk8PHs2Xi1 !

A new paper presents a statistical framework for power analysis of spatial omics studies, facilitated by an in silico tissue generation method. @ethanagb @DenisSchapiro @mssanjavickovic @broadinstitute @HiTSatHarvard OA paper:

When the method section leads to a citation... Which leads to another citation... Which leads to a paper from the 70s that isn't online