Sten Linnarsson
@slinnarsson
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Professor of Molecular Systems Biology at Karolinska Institutet. Moved to https://t.co/RutSid6fAz
Joined June 2009
We’re looking for a PhD student in brain onco-immunology! Apply here, one week to go:
kidoktorand.varbi.com
Are you driven by a desire to contribute to groundbreaking medical research? The Sten Linnarsson Lab , part of the Unit of Molecular Neurobiology at the Department of Medical Biochemistry and Bi
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I stopped posting here a long time ago when X took a sharp right turn into the gutter. But I miss Science Twitter. Now it looks like it’s being reconstituted at Bluesky! I’ll be at https://t.co/Ye9wmOWWHc (to get started finding people, look for ”starter packs”)
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We are very excited to present a major breakthrough achievement – the de novo design of synthetic enhancers for selected tissues in fruit fly embryos in vivo using deep- and transfer learning, @deAlmeida_BPet al published today in @Nature
https://t.co/TIlPrBKYaK. Thread 👇(1/N)
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Exciting news! Our latest research on "Cell type directed design of synthetic enhancers" has been published in @Nature. We've harnessed deep learning to design enhancers with cell-type specificity. Find our paper here: https://t.co/wC44fDMp70. Highlights below: [1/n]
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Nature research paper: Cell type directed design of synthetic enhancers
nature.com
Nature - Deep learning models were used to design synthetic cell-type-specific enhancers that work in fruit fly brains and human cell lines, an approach that also provides insights into these gene...
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Method sections should contain all the info needed to replicate a study. But the level of published detail can vary considerably. @LarsBorm (@slinnarsson lab) explains how he makes complex research protocols understandable. @nature @NatureCareers
nature.com
Nature - New wet-lab methods can be hard to share owing to their complexity, but with a little extra effort, you can give users a leg-up in getting started.
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Seriously @MIT - ”CRISPR-based genome editing tools developed by MIT professor and McGovern investigator Feng Zhang, Abudayyeh, Gootenberg, and others” - ”others” is doing a lot of work in that sentence… (but @zhangf Fanzors are very cool)
news.mit.edu
Species from snails to algae to amoebas make programmable DNA-cutting enzymes called Fanzors, and a new study from MIT’s McGovern Institute has identified thousands of them.
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We are looking for computational biologists who are interested in one of the following topics: protein design and engineering, biosensor development, single-cell technologies. Please send me a message or email if you are interested.
ki.se
Our research group is interested in the molecular mechanisms influencing experience-driven activation and equilibration of neuronal circuits in the mouse brain.
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Human brain atlas papers by @kimsiletti @MossiAlejandro @ka_wai_rine
@ErnestArenasSWE @EmelieBraun1 @MiriDanan Rebecca Hodge Trygve Bakken Ed Lein @LarsBorm Elin Vinsland Erik Sundström and many others. With a stunning double cover illustration by @IKapustova
In 21 papers across Science, @ScienceAdvances, and @ScienceTM, researchers with the #BICCN consortium present an atlas of the human and nonhuman primate brain in unprecedented detail. The results uncover the genetic organization of the human brain. https://t.co/K3ePBMRzli
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In several parallel projects now published in @ScienceMagazine, @slinnarsson's group at KI and colleagues @humancellatlas have created the most comprehensive atlases of human #brain cells to date, providing clues on different brain diseases. #neuroscience
https://t.co/K0IsdG5r9m
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I am shocked at the violence and barbary displayed today by Hamas and its followers. My thoughts are with all my scientist friends in Israel, at Weizmann, Technion and elsewhere. Be safe, be safe.
קהילת מכון ויצמן מתאחדת בצער עמוק על מותם של חפים מפשע ומייחלת להחלמתם של הפצועים ולשובם של השבויים, החטופים והנעדרים בשלום. בשעה קשה זו, אנו מחזקים את תושבי כל ישראל, כוחות הביטחון וההצלה ומקווים לימים שקטים יותר. שמרו על עצמכם ועצמכן. In light of the recent events, the
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We're proud to present our latest @CD_AACR study, in collaboration with @ErezNeta, unraveling the intricacies of immune cells in breast cancer metastasis & revealing that TREM2 macrophages regulate the invasive margins of metastases. >>> https://t.co/GNrL6E4m5o (1/12)
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PLEASE consider joining our #singlecell #spatial genomics group @cnag_eu in beautiful Barcelona! #lifeisbetteratthebeach Senior Laboratory Technician https://t.co/5qN8pZzTRT Postdoctoral Computational Biologist https://t.co/o8QzM5Rsjm Please RT.
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We're so excited to share our latest work “Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in #Glioblastoma” spearheaded by @OghuzhanKaya on the wet & @LCForst on the dry lab as a preprint @Biorxiv
https://t.co/r4od0M6d5D
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Really happy to present our work combining Molecular Biology and Electronics just published in @ScienceAdvances A great collaboration with Mehdi Javanmard @RutgersECE and @LarsMSteinmetz #LAMP #AMR #infection
science.org
Electronic detection of self-assembled DNA nanoballs enables simple label-free pathogen detection.
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Massive opportunity alert! Start your new independent lab in any area of experimental or computational biomedicine, in our department at @karolinskainst. We offer a 1.1 M€ ($1.2M) startup package, amazing colleagues and a beautiful lab environment.
ki.varbi.com
We seek inspiring, creative candidates that want to start their careers as independent researchers at the department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet . We are one of
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