The vaccine against Shingles helps protect against dementia, results of a natural experiment, adding to prior evidence "implications are profound" New @Nature https://t.co/NmazPQdos2 https://t.co/HnBsMQYWfT

Congrats @alvarfparis Great to see this out

Today we’re launching the world’s most comprehensive study of proteins circulating in our bodies, which will transform research into new medical tests, drugs and treatments. Discover more: https://t.co/o8t2yuknLv

Thanks Joe! I’ll be honest we were mildly disappointed to find no ‘smoking gun’, I.e a disease-specific signature of clonal expansion. For me has highlighted how valuable it is to have positive disease controls to avoid making spurious claims of disease specificity!

V pleased to share our paper on the immune landscape of CSF in MS and other conditions https://t.co/9WBk7FLng6 now out in @CellRepMed Fun and stimulating collaboration with co-first author @ChristieGasperi and senior authors Maria Ban, Steve Sawcer and Bernhard Hemmer

There is discrepancy between self-reported and objectively assessed cognitive functioning in #MultipleSclerosis, suggesting we shall use networks of PROMs and cognitive domains. Study from @maureen_dam @MScentrum020 @amsterdamumc @UniLeidenNews ▶️ https://t.co/7LxI8TsvXK

Looking for new post doc role in 2026? 3 year contract working on proteomic data for AD and PD in Oxford. Do get in touch with any questions - would love to hear from you.

✅ The UKB-RAP Transition Credits Programme is now open! Thanks to @wellcometrust, researchers can apply for £1,000 credits to help cover costs of using our data, with enhanced support available. Apply now & accelerate your research! More info: https://t.co/lOQnKQasil

The newest @RegeneronDNA method, REMETA, from Tyler Joseph, @marchini, and co. is a game changer - enabling the ability to reconstruct gene-based test associations from single variant summary statistics (and LD).

Introducing a new method called REMETA from the Regeneron Genetics Center (RGC) @RegeneronDNA for meta-analysis of gene-based tests using summary statistics https://t.co/Bv3pqMB1iy This is great work from Tyler Joseph. Pre-print is here​ https://t.co/CffQXSZPv2

Tandem repeats (TR) are usually underxeplored in genetic studies🧬 Here, a PheWAS of TRs in UK Biobank 👉N=168,554 👉47 TRs show significant associations with 73 traits 📜paper: https://t.co/zK5kOFSg0x

📢Please, RT: do you need to run GWAS, their imputation/meta-analyses/follow-up, PRS & MR? Apply for Short online live course "Introduction to GWAS" by Dec 20, 2024 https://t.co/jdokiFzjGC 12th edition, over 530 scientists trained thus far! @eshgsociety supports fellowships

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GxDrug interactions now published at cell genomics :) @sadowskimich did a ton of great work in this paper. We hope the approach is a step toward improving predictions for individual-specific treatment response

"GWAS of Extended Prescription Analgesic Use Identifies Novel Genetic Loci in Chronic Pain"

Calling all medical students…

Please RT! This was such an enjoyable event last year. Registration now open. Free registration for early careers researchers and clinicians in training who submit an abstract

One of the strongest risk loci for SLE lies on the MHC region. Earlier work by Steve McCarroll's group (Kamitaki et al Nature 2020; https://t.co/G1Qdm9Tn8d) used African ancestry samples to break down the LD between HLA and Complement gene variants and showed that the risk locus

This is great news (COI: I am a long established consultant and shareholder to @nanopore) - epigenetic information on long reads at scale! (bonus - also excellent SV resolution coming our way). Haplotype methyl+hydroxymethyl resolution. 50,000 and then hopefully the full 500,000.

In a cohort of 51,170 South Asians, #PolygenicRiskScores identified genetic susceptibility to insulin deficiency and fat distribution as key factors in young onset #Type2Diabetes and its rapid complications. #DiabetesPrevention #ChronicDiseases https://t.co/jQHEUbUd4S