Rupert Beale
@bealelab
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Cell Biology of Infection Lab @thecrick. Legacy verified account. Nephrologist. Own views. Mostly using Blue sky now, same handle.
Cambridge/London
Joined June 2012
We’ve worked out how the molecular machines that create acidic compartments can recruit autophagy (self-eating) machinery when they can’t maintain a pH gradient. We are really pleased with this discovery, out in @MolecularCell
https://t.co/XOFj4lJ2I7. 1/16
cell.com
Timimi et al. reveal that the targeting of de-acidified compartments with ATG8s is mediated by a direct interaction between the V-ATPase subunit V1H and ATG16L1. This interaction is important for...
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I can't sleep. I've just looked at Lord Birt's and Lord Pannick's amendments first reported by @Telegraph. They say it delivers a 'separate service' within the NHS, but it's a charter for abuse, fast-tracking ending lives with a cheery navigator 1/
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I’m still not sure how, of all healthcare professionals with expertise in this area, it was Marsh who got the opportunity to once again share his personal opinion (although I appreciated his candour). In terms of favouring the choice that benefits the majority at the cost of
The terms “risk” and “cost” are euphemisms in this context, used to step around the truth. He is talking about a person being coerced to take lethal medication to end their life. And he appears to treat that person’s life as an acceptable price to pay to push this law through.
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The Terminally Ill Adults (End of Life) Bill is not about alleviating suffering, there is no guaranteed choice of palliative care, the “protections” against coercion are inadequate. If MPs wanted such a Bill they could have sent us one. They didn’t.
If the Lords can *ever* vote any bill down, it's hard to think of one which would more fully meet the criteria: - serious rights concerns - skimpy Commons process - not a manifesto commitment / not even a govt bill
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In light of Lord Falconers closing speech today, I’m reposting this thread on why we would assess capacity differently for a request for assistance to end one’s life compared to a refusal of life-sustaining treatment (such as withdrawal of ventilation)…
The TIA bill committee seem v confused about the difference btw assisted dying and refusal of life-sustaining treatment. It comes up again and again, esp from @LewisAtkinson So here’s a brief explainer 👇🧵
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This is absolutely critical. If a patient tells me they want to die, how would I know whether the appropriate response is suicide prevention or suicide assistance? What would this decision be based on - a hunch?
Lord Goodman (@PaulGoodmanCH) points out that psychiatrists are trained to help prevent suicide, not authorise it. Using the Mental Capacity Act to authorise assisted suicides would confuse the role of psychiatrists and even place them at criminal risk under this Bill.
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Two points on this letter about the Lords' role in relation to the Terminally Ill Adults Bill. First, contrary to the letter, there is no consensus that it is improper for the Lords to refuse to approve a non-manifesto Private Members' Bill. See:
publiclawforeveryone.com
The Assisted Dying Bill has been approved by the House of Commons. But to become law, it also needs the approval of the House of Lords. What constitutional role will the Lords play in this process …
NEW: 65 peers have written to all lords urging them not to block the bill. “It is not our role to frustrate the clear democratic mandate” of the Commons. Signed by the likes of Neil Kinnock, Ruth Davidson, Robert Winston and others.
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Absolutely agree with @HackneyAbbott (and all the medical Royal Colleges) that the bill is not fit for purpose. It's extraordinary that it ever got this far. Damning indictment on Starmer's 'leadership' that it's still getting tacit Government support.
Good. This is a dangerous Bill, and it should be blocked. Peers in fresh push to block assisted dying bill https://t.co/RM07wRWPeK
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I am second on the list of amendments tabled. Some are around using the correct language in the equality act. Others are around pregnancy. The bill is light on this. Many are safeguarding amendments. Ask me why I’ve tabled so many versus other bills. There are big gaps
Good. This is a dangerous Bill, and it should be blocked. Peers in fresh push to block assisted dying bill https://t.co/RM07wRWPeK
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Lord Shinkwin, one of a few disabled peers, raising concern that reasonable adjustments are not being made to allow disabled peers to participate. Govt/Falconer was pushing for House to sit longer than 3pm (the normal time). Has written to PM and Chief Whip for reassurance
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Day 1 of Committee of Whole House on Starmer's ill thought through vanity project will start shortly. I'll try and pull out key moments. Watch BBC Parliament if you'd like the names of the peers speaking: https://t.co/94zQFwbm03 Or Parliament Live:
bbc.co.uk
Coverage of proceedings in the House of Lords on Friday 14 November.
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Here are nine reasons why the Complex Life and Death Decisions (CLADD) group at @KingsCollegeLon believe the Terminally Ill Adults bill is bad law as currently drafted 👇
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I can't think of another piece of legislation so ostentatiously championed by privilege, so driven by corporate opportunism, so precisely targetted at the vulnerable, so marinaded in supersition. This is what the Great Reform act was supposed to prevent.
At the Joint Committee on Human Rights today, @thelizcarr makes an excellent point. The one safeguard that is needed is that #assistedsuicide remains illegal. Bravo!
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Prob for whoever briefed last night in knowledge Wes Streeting on media round today is that Streeting is such a pro. Effortlessly batted it all off while showing why he'd be so much better at talking to the public than Starmer. Talk about self-defeating 😂
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https://t.co/9gjcXeepMo This report by the All Party Parlimentary Group on Emergency Care went under the radar yesterday (the media was distracted) but contains some really important information. A rambling thread 1/n
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The important story behind this story is that someone in Downing Street is having a breakdown:
theguardian.com
No 10 said to be in ‘full bunker mode’ over fears of attempt to oust him after budget or May local elections
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FWIW this NHS worker has overall a favourable view of Wes Streeting. Definitely less bad than many recent Health Secretaries.
Via @Ipsos_in_the_UK in September Keir Starmer Favourable 21% Unfavourable 54% Wes Streeting Favourable 19% Unfavourable 32%
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SUPERB and angrily unvarnished response, by former BBC chairman, Lord Patten. "I don't think that we should allow ourselves to be bullied into thinking that the BBC is only any good, if it reflects the prejudice of the last person who shouted at it." ~AA
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Pleased to share the voices of children at the Terminally Ill Adults (End of Life) Bill Committee this afternoon. We must be more cautious around assisted dying, especially for vulnerable children inc those with disabilities who face challenges transitioning to adult services.
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This is shocking. An assisted dying law that would apply to Pam would be dangerous to many thousands more disabled people. Surely it cannot proceed.
Under a decision made by @SP_HSCS this morning, I would be eligible for assisted suicide. The committee rejected placing timescales on prognosis. This means anyone with an illness that could result in their premature death is eligible. (1)
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Rail worker injured as he protected passengers during mass stabbing on UK train named as Samir Zitouni
bbc.co.uk
The family of rail worker Samir Zitouni say they are "immensely proud" and he has "always been a hero".
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