Armand 🏡 Profile Banner
Armand 🏡 Profile
Armand 🏡

@armandcognetta

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766

Now: making drugs with superpowers @proxbio , mentor @beondeck (ODLB), advisor @menten_ai Past: @Alnylam , @scrippsresearch , @InzenTx , @ycombinator W20

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Joined April 2019
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@armandcognetta
Armand 🏡
2 months
when you send a 🔥 investor update
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@armandcognetta
Armand 🏡
11 days
has anyone else tried ~jhana meditation but for sleep? access concentration -> find a sleepy feeling in your body -> shift your concentration there and let it expand through your entire consciousness -> become extra sleepy, fall asleep
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@armandcognetta
Armand 🏡
4 months
Inbound to @KeystoneSymp Proximity Based Therapeutics with proximity legend @MichelleArkin et al
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@armandcognetta
Armand 🏡
3 months
so fucking epic/surreal to vote for my bff @Mtclai ! LFG!!!
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@armandcognetta
Armand 🏡
3 months
I'm hiring a principal scientist/director at @proxbio to take over my role of leading the absolutely stellar group of scientists on our platform team. Strong chem bio + proximity background is best, but leadership skills are most important. Please share + DM if interested, ty! :)
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@armandcognetta
Armand 🏡
6 months
most unexpected outcome of the OpenAI saga for me was my mom texting this morning asking if I knew who Mira Murati was and that she was single
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@armandcognetta
Armand 🏡
7 months
recently got some unbelievably cool data for one of our lead programs, will be a while until we can share publicly but man it's gonna be huge! I love my job 😇
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@armandcognetta
Armand 🏡
17 days
high throughput phenotypic screening is our best bet to solve the most important challenges in drug discovery right now, and the ability to do this in vivo is huge! it's been awesome to watch @GordianBio 's progress over the years from up close, can't wait to see what's next 🚀
@GordianBio
Gordian Biotechnology
17 days
Shouldn’t aging be part of drug discovery for diseases of aging? Gordian exists to move therapeutic testing from plastic wells and young mice into a living environment with all the complexity present in patients with age-related disease. We’re now…
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@armandcognetta
Armand 🏡
4 months
Michael is simply one of the best there is, and I know of no other person with more potential to change SF politics for the better than him. He is one of the rare individuals possessed of both deep kindness and empathy coupled to absolute, unstoppable hyper-competence. A…
@Mtclai
Michael Lai 赖天宸
4 months
I’m running for office for San Francisco DCCC on March 5th, 2024! In the city where ppl are building AI & longevity drugs, it's crazy that the basics don't work: Streets are unsafe New housing is blocked We don't teach 8th grade algebra I'm running to change SF 🧵
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@armandcognetta
Armand 🏡
8 months
Build now, age later 🚀 Proud to be a @LongevityFundVC portco.
@LauraDeming
Laura 🌲 ⛰️
8 months
Excited to launch a new fund today: I wrote here about my takeaways from the past decade + predictions for the next:
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@armandcognetta
Armand 🏡
11 days
for jhana meditation you create a runaway positive feedback loop by finding a positive sensation, focusing on it completely which creates more positive sensation, focusing on that newer/stronger positive feeling, repeat until bliss you could imagine creating a runaway positive…
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@armandcognetta
Armand 🏡
29 days
lesgoooo!
@katclone
Kat
30 days
the only influencing I want to do on here is to convince ppl to go out & stop procrastinating getting healthier ty @armandcognetta for motivating me to get back into distance running LFGGGG ~230 mi of outdoor runs logged since Feb 17
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@armandcognetta
Armand 🏡
2 months
SF is a beacon of the free world. Tomorrow you can vote to save it
@Mtclai
Michael Lai 赖天宸
2 months
voice is back today! i had to say this: the margin for victory for the last seat on the DCCC in 2012 was 32 votes (!!). with two days until the election can you text 3 friends about me and @SFDemsForChange ?
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@armandcognetta
Armand 🏡
4 months
people who say ideas don’t matter have never experienced, on a gut level, how powerful a truly good idea can be ideas are everything (execution is important too tho)
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@armandcognetta
Armand 🏡
7 months
I had a very special weekend marrying two of the best people I know 🤗
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@armandcognetta
Armand 🏡
1 year
@Aella_Girl CBTi fixed this for me
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@armandcognetta
Armand 🏡
22 days
was rereading the acknowledgements section of my thesis about all the clubs I helped instigate in grad school and realized I was meant to be a founder
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@armandcognetta
Armand 🏡
4 months
kenshō
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@mbateman
Matt Bateman
4 months
Your periodic reminder that the body also keeps the score for good things, not just trauma
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@armandcognetta
Armand 🏡
3 months
@AmitDeshwar @nearcyan @slatestarcodex One major hypothesis is just that FAAH/anandamide don’t modulate pain in humans to the same extent they do in rodents (where most of the studies showing analgesia come from). The FAAH-OUT person is perplexing but could be that congenital FAAH inhibition turns off pain signaling…
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@armandcognetta
Armand 🏡
5 months
@Atelfo Here's another way to put this: our current therapeutic modality toolkit still only gives us the most crude level of biological control. EG most small molecules (other than GPCR drugs) are inhibitors. It's a general physical principle that it's easier to break something than it…
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@armandcognetta
Armand 🏡
9 months
live every day like it's the first day of suffertember
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@armandcognetta
Armand 🏡
11 months
Wed morning volunteer group at @GLIDEsf 🤗
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@armandcognetta
Armand 🏡
17 days
when someone on your team tells you this is the best job they’ve ever had 🥰
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@armandcognetta
Armand 🏡
3 months
A+++ life advice: "Passionately launch into an ambitious public-facing project."
@TylerAlterman
Tyler Alterman
3 months
I wrote & analyzed a 20-person list of anyone I've seen go sustainedly super-saiyan (i.e., anyone who's become radically more capable of creating what they want to see in the world). 18/20 all did the same thing. Can you guess what it was? Hint – it wasn't a: • transformative…
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@armandcognetta
Armand 🏡
5 months
@Atelfo Excellent read! The only part I disagree with is: "The most significant factor preventing us from taking better molecules into clinical trials is not our ability to design arbitrary molecules, but our (lack of) understanding of underlying disease biology. In other words, we…
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@armandcognetta
Armand 🏡
1 year
just hit inbox zero for the first time since starting my co, what is this magical feeling 😇
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@armandcognetta
Armand 🏡
3 months
how could you not vote for this guy?! 🔥🔥🔥
@Mtclai
Michael Lai 赖天宸
3 months
Called a voter last night, and it was wild to hear: "oh I saw you on TV!" Fun to be in this @GrowSF TV ad. I'm grateful for all of their work to elect outcomes oriented leaders to fix SF.
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@armandcognetta
Armand 🏡
7 months
excited to be co-hosting!
@kulesatony
Tony Kulesa
7 months
📢 The 2023 Founder-led Biotech Tour In November, we're teaming up with 50+ founders to bring the community together in four cities. SF: 11/2 Boston: 11/7 NYC: 11/9 London: 11/13 + virtual events including co-founder matching, speed networking, and more.
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@armandcognetta
Armand 🏡
29 days
longevity field needs more people who actively exemplify longevity habits
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@armandcognetta
Armand 🏡
10 months
In Boston this week and NYC next! Who should I meet?
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@armandcognetta
Armand 🏡
10 months
. @goodreads is a dating app
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@armandcognetta
Armand 🏡
4 months
@catehall Something I’ve learned is that there is a distinction between just acting with agency and actually feeling on a gut level that you have agency (which then also naturally leads to acting with agency). The latter is better but I think a lot of people get stuck in just the former.
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@armandcognetta
Armand 🏡
9 months
@bashu_thanks recently I've been saying "good job Armand!" in my head all the time for everything it's basically the opposite of constant negative self-talk
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@armandcognetta
Armand 🏡
2 months
new teammates r cool
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@armandcognetta
Armand 🏡
11 months
@ashleydzhang DC: Capitol Hill Books and The National Portrait Gallery
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@armandcognetta
Armand 🏡
4 months
self-trust is what you do, not what you think
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@armandcognetta
Armand 🏡
4 months
@pottslab Really interesting. I wonder what % of the time you'd see neo-interactions like this if you took a protein array and incubated it with any protein +/- a diverse set of ligands for that protein. My guess is that it may be more common than people think
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@armandcognetta
Armand 🏡
5 months
what the fuck
@BillAckman
Bill Ackman
5 months
The presidents of @Harvard , @MIT , and @Penn were all asked the following question under oath at today’s congressional hearing on antisemitism: Does calling for the genocide of Jews violate [your university’s] code of conduct or rules regarding bullying or harassment? The…
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