I feel like each year I realize how much I don’t know and how ignorant I am and it’s *awesome*. Like, how exciting is it that you *don’t* already know all there is to learn?

I really wish there was a Stratechery for deeptech in different industries (ie nuclear, neuro, etc) - has anyone written such a thing?

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are there any good books on the qualia of mathematics? like Polya's 'How to Solve It' but including what kind of qualia one might experience along the way? Hadamard on the psychology of mathematical invention comes to mind, but I want something a bit more tactical?

so cool that you can reversibly cryopreserve human embryos for 30+ years and still get a live, healthy birth https://t.co/3rworzB7LY

watch this space :)

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someone once told me that being an entrepeneur is like being a psychological endurance athlete and it was one of the most helpful frameworks I've ever internalized (not apropos of anything happening rn, just felt like sharing)

I don't...buy the ergodic hypothesis in stat mech. Any recs for how to get comfortable (even empirical?) Seems just obviously not something that follows from first principles - unless it's like every system is noisy and that's why? But aren't there attractor trajectories that

any recs on using AI image / video gen tools for precise scientific illustrations / graphics? would love any examples of this done well also! most of the stuff I'm interested in modeling are general properties of groups of molecules moving around

hm, it was originally introduced in the context of a geometric representation of what systems were likely to do - I'm curious if this perspective (very visual) is some missing part of the puzzle Maxwell making a clay model of the landscape for Gibbs! ->

like d'aww yes of course that is a little ice embryo that wants to grow! but hopefully just not in living tissue!

ChatGPT keeps (mistakenly) saying 'ice embryos' instead of 'ice nuclei', which is honestly just so much cuter

Trying, once again, to actually understand what 'free energy' means - would love any help/pointers! - if it were renamed, what do you think it should be called instead? - what are your favorite thought experiments / toys that involve free energy? - what isn't true about it, that

currently on the conversation menu - philosophy (what form of personal identity does technology want us to take) - how to live a good creative life while building deep tech products that reach patients - how are you??? humans vibing haha - if you understand Galois theory or group

will be at the transhumanism workshop at @edgeesmeralda this Thursday 5/29, curated by @katherinebaney :) - curious to say hi to some new friends while I'm there, DM if you want to meet up!

Really enjoyed talking to Joe! We focused on things I don't normally speak about publicly (personal identity, humane transhumanism, new thinking latent spaces for scientific discovery) Thanks @JosephNWalker for facilitating a convo that very current - amazing prep :)

draft #41 problems - have any of you tried to 'show' idea that is so incoherent and mysterious (like, it has structure, but it's much larger than you can see), but is also saying something *very particular* - how do you effectively transmit the latter, while retaining room for

my mom is graduating law school today!!! so excited, love you mom ❤️❤️❤️

I'm curious who this generations PG is (updated for building on accelerated timelines w still operating from high agency) - I feel (in retrospect) so amazed and grateful for the level of thoughtfulness and kindness that his essays had (he wrote a whole essay about why it's safe

in ~15 years, metastatic melanoma went from a disease with a median 6 month survival time to one where 52% of patients have melanoma-specific survival 10 years out may we all get a chance to work on medical technologies like this - my god! https://t.co/n5Htxe7ZSI

I feel like you can tell how happy I am by the number of https://t.co/bBCzFCoazL tabs open in my browser

I feel like there's a phase of writing about an idea where you are totally in love with it and unable to see its flaws, and then there is a phase where it feels like a long-term partner - you are intimately aware of its flaws, its changed you, deeply, trying to explain it clearly