John Schoggins
@jschoggins
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Professor curious about how mammals 🧘♂️🦇 🐭 fight viruses🦠Devote inordinate amounts of time to yoga, breadmaking, coffee. Views my own.
Dallas, TX
Joined August 2014
In 1986 Staeheli et al seminal MX1 paper noted re: IFN/ISGs “it is not known...how many of these proteins are required for protection against a particular virus”. 37 yrs later, Phd student @mattbmcdoug's new paper shines a light. 1/3 https://t.co/HFnGhDImg5
embopress.org
image image ZAP, IFIT3, and IFIT1 are dominant effectors that restrict Venezuelan equine encephalitis virus, while comprising < 0.5% of the total interferon‐induced genes. Viruses may thus be...
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Very proud to have our lab's first work published in @cellhostmicrobe! In this work, we use functional metagenomics to find phage defenses from human and soil microbiomes! Congrats to first author @luis840alberto ! https://t.co/qS2UMC7dBL (1/3)
cell.com
Rodríguez-Rodríguez et al. use functional metagenomics to identify hundreds of sequences from diverse environmental bacteria that block phage infection when expressed in E. coli. Their discoveries...
My lab’s first preprint! We used functional metagenomics to identify phage defenses in human and soil microbiomes. We scaled these selections while maintaining accuracy, enabling us to examine 9 habitats for defense elements against 7 phages. https://t.co/M9JGVJ7lVy 1/10
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📢 UT Southwestern Office of Safety & Business Continuity is hiring a Biological Safety Specialist Lead/BSL-3 Coordinator! Lead BSL-3 safety programs and ensure compliance. Bachelor’s + 4 years of experience required, BSL3 experience preferred. Apply now! https://t.co/dU0fzPcDS3
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Are you interested in pursuing a degree in biomedical sciences? Join the @UTSWGradSchool community that provides exceptional mentorship and multidisciplinary training. Explore our innovative research and exceptional educational opportunities now! https://t.co/3xSHbj7POk
#UTSWedu
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We officially launched our new publishing model in January 2023. Today, join us in looking back on a year of activity supporting this alternative approach to research communication with our 2023 Annual Report: https://t.co/q41Qnrto37
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Faculty search announcement: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) https://t.co/4EbIdGIN9g
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Congrats to Maggie Wang, a @UTSWGradSchool student in the Gao Lab for winning the 2024 Ida M. Green Award! Her research targets therapies involving the STING protein's immune mechanisms. Learn more about Maggie’s innovative research and impact: https://t.co/yWN1zAPCNd
#utswedu
utsouthwestern.edu
Graduate student Maggie Wang’s research of a protein involved in cancer immunotherapy led to her winning this year’s Ida M. Green Award.
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We're excited to announce Julie Pfeiffer, Ph.D., as the new Chair of #Microbiology at #UTSW. In a recent Q&A, Dr. Pfeiffer outlines her vision for advancing microbial science and boosting our research capabilities. Learn more about her plans: https://t.co/LqqRvvn72d
#utswnews
utsouthwestern.edu
Julie Pfeiffer, Ph.D., whose discoveries launched a new discipline of microbiology studying transkingdom interactions, has begun her new role as Chair of Microbiology.
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We’re inviting papers to an upcoming Focus Issue on #TrainedImmunity and are particularly interested in maladaptive innate immune memory: https://t.co/ixjR1GWt1o
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Why does @eLife only review some papers and not others? We (Editorial Leadership, Senior Editors, and Early Career Advisory Group) explain why in this new editorial. 👇 Hope this helps clarify the process! https://t.co/vkcxhlUvdv
elifesciences.org
When deciding which submissions should be peer reviewed, eLife editors consider whether they will be able to find high-quality reviewers, and whether the reviews will be valuable to the scientific...
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My review about “The HIV-1 transcriptional program” for the @JMolBiol special issue on transcription elongation is now out: https://t.co/qW2WS3gKSc. I provide a 4 decades historical recount from mechanistic insights to implications for viral latency and cure. Thanks @NIAID!
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The major paper from my PhD thesis with @dorsolab has now been published in @NatureComms: https://t.co/26t7Ren6Sf KAP1 negatively regulates RNA polymerase II elongation kinetics to activate signal-induced transcription. Tweetatorial below!
nature.com
Nature Communications - Here, the authors implement acute factor depletion and demonstrate that the transcriptional regulator KAP1 facilitates signal-induced transcription activation by negatively...
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For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. https://t.co/J9xnnt0xXD
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🎶 3-2-1! Contact, is the secret, is the moment When everything happens Contact, is the motion, is the reason When everything happens Contact! Let's make contact! 3-2-1 Contact! 🎶 So vintage, but this show definitely shaped an early love of science. https://t.co/1S0eCOks2d
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This landmark #ReviewedPreprint represents “the most significant breakthrough in membrane and secretory biogenesis in recent years.” ‘Structural analysis of the dynamic ribosome-translocon complex’ https://t.co/03eD9vjm54
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A new class of bacterial defence systems against genetic parasites.
elifesciences.org
A new class of bacterial defence systems against genetic parasites has been revealed.
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📢 Meet our newest editors! Bringing a broad range of experience, since May last year, we are thrilled to welcome 10 new senior editors and 116 reviewing editors. https://t.co/kuHExZw9xJ
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Path of totality and fairly clear skies in Dallas…gotta say, that was pretty impressive.
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