Activation of a specific cell signaling pathway has been shown to protect blood vessels from hypertension-induced damage, highlighting new potential targets for future blood pressure therapies. @jbiolchem

#A novel fluorescent drug enables surgeons to visualize nerve tissue in real time, enhancing precision and potentially reducing nerve injury during complex surgical procedures. @unm @NatureComms

#Uncertainty, not just social context, activates the brain’s mentalizing network when inferring others’ thoughts, suggesting a broader role for uncertainty in social and nonsocial cognition. @Penn @sfnjournals

#Multisensory virtual #Forest environments combining sight, sound, and scent significantly enhance mood and nature connectedness, suggesting potential for stress relief in settings with limited nature access.

#Neurocomputational analysis using fMRI and language models shows the brain organizes conversational meaning differently during speech production and comprehension, advancing understanding of real-time dialogue. @NatureHumBehav

##GeneTherapy using AAV vectors restored significant hearing in children and adults with OTOF-related #CongenitalDeafness, with rapid improvement and no serious adverse effects observed. @NatureMedicine

#A two-layer neural model now matches the complexity of #VisualProcessing in the brain, accurately predicting individual neuron responses with greater simplicity and interpretability. @NatureComms

#Microplastics have been identified in human follicular and seminal fluids, with PTFE being the most prevalent polymer. The implications for fertility and #ReproductiveHealth remain under investigation. @ESHRE

##Psilocybin reorganizes neural circuits in the #RetrosplenialCortex of mice, enhancing fear extinction and behavioral flexibility by suppressing fear-active neurons and recruiting extinction-active populations. @NatureNeuro

##Betaine, a molecule boosted by sustained #Exercise, inhibits key inflammatory and aging pathways, suggesting potential for exercise-mimetic therapies to support healthy aging and metabolic function. @CellCellPress

Neurons can transfer #Mitochondria to #Cancer cells, boosting #Tumor metabolism and metastatic potential. Disrupting nerve input reduces tumor invasiveness and deprives cancer cells of key bioenergetic support. @nature

Rerouting bile acids after #GastricBypass surgery suppresses colorectal #Tumor growth and metastasis in mice, independent of #WeightLoss, highlighting bile acid metabolism as a potential therapeutic target. @sciencetm

#Earlier bedtimes are linked to higher levels of next-day #PhysicalActivity, even when #SleepDuration remains constant, suggesting sleep timing plays a key role in promoting active lifestyles. @PNASNews

#New evidence indicates that triglycerides stored in #LipidDroplets can serve as an alternative energy source for neurons, especially when #Glucose is scarce, reshaping understanding of brain metabolism. @WeillCornell

A GLP-1 receptor agonist, similar to Ozempic, reduced monthly #Migraine days by nearly half in chronic #MigraineSufferers with obesity, suggesting a potential new treatment pathway.

#Projected US #ForeignAid cuts could result in over 14 million preventable deaths by 2030, with significant increases in child mortality and setbacks in global health progress. @TheLancet

Targeting inflammation in #BrainBloodVessels has been shown to promote repair and functional recovery in #VascularDementia models, highlighting a promising therapeutic pathway for intervention. @CellCellPress

A newly engineered protein selectively silences tissue-damaging #TCells, reducing autoimmune responses in mouse models of type 1 diabetes, hepatitis, and multiple sclerosis. @nyulangone @CellCellPress

#HormoneTherapy type may influence #BreastCancer risk in women under 55. Estrogen-only therapy is linked to lower risk, while estrogen plus progestin therapy is associated with higher risk. @NIHforHealth @TheLancetOncol

Low-intensity transcranial magnetic stimulation boosts synaptic turnover in Alzheimer’s mouse models, suggesting potential to restore neuron health and enhance #SynapticPlasticity in neurodegenerative disease. @SPIEtweets