Very happy to change my profile picture to a fella. #NAFO is an amazing way to support Ukraine, in a time where 🇷🇺 relentlessly bombs 🇺🇦 civilians in the most abject way. Check out @Official_NAFO if you're interested to contribute too.🌻 🇺🇦 must & will win this war #СлаваУкраїні

It is finally out! Muntathar Al-Shimary, Doudna Lab, @bradyfcress and I present a gene knockdown tool that works in diverse phages: CRISPRi through antisense RNA Targeting (CRISPRi-ART)! Check out the final paper in @NatureMicrobiol https://t.co/DJkBM5fhPL

We shouldn't be afraid of Russia ☢️🇷🇺☢️ What many failed to understand is that Putin is not crazy nor stupid. He is even quite clever. He understood we are weak. He understood we are afraid by his power. We shouldn't. 🧵THREAD🧵1/25 ⬇️

Published today @NatureComms We discovered a bacterial NLR-like pattern recognition receptor that can sense 3 different viral proteins as a signature for infection. This explains its broad defense against different phage families Congrats @nath_bechon! https://t.co/ietOyj6Ngu

Fancy a postdoc in Munich? For a collaborative project between @SorekLab and @hornung_lab on antiviral innate immunity, we are looking for exceptional candidates with skills in immunology / biochemistry / computational biology. More details here: https://t.co/VXPNk8Wi3R

This Is Spectacular

🦠🧬Our paper is live @CellCellPress: Genome integrity sensing by the broad-spectrum Hachiman antiphage defense complex https://t.co/id7uU1YRIe Through structural, genetic and microbiological approaches, we show that Hachiman degrades DNA… by sensing low integrity DNA.

What kind of childhood makes a top scientist? Is it enough to have all the right traits (brilliance, grit, etc) or do you need the right family too? And why should we care? A 🧵 on our paper on the Nobel Laureates. A teaser: the income distribution of the laureates' fathers.1/N

Exciting and fantastic work - the new peak of recent studies reminding us that viruses are not the only mobile elements with their own evolutionary agenda! 🧬💪🏼👇🏼

You are looking for a PostDoc position or know someone who is? We are looking for someone to join our team at @ETH_en Zürich for a project on phage-host interactions of Pseudomonas aeruginosa 🦠🧬👇🏼

Are you planning to visit Ukraine soon? Or would you like to show your support and learn a little Ukrainian? Check out this short glossary of the most useful words and phrases. 🧵(1/10)

Our paper out today @nature: phages reconstitute NAD+ to counter bacterial immunity Phaged invented a new biochemical pathway for NAD+ synthesis - including previously unknown enzymatic reactions - to evade bacterial defenses Congrats @IlyaOsterman! https://t.co/JuzwDHmlFU

In a new study, we report the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of mammalian innate immunity!! Co-led with @EnzoZ_P lab, in collab with @morehouse_ben https://t.co/AvaPknd6XX

Almost two years ago I joined @MDMlab_Paris and @Poirier_Lab to study the conservation of immunity between prokaryotes and eukaryotes, and our paper is out! While I didn't move country between PhD lab and postdoc lab, I did move from a bacteria-focused lab (hi @epcrocha ) to...

No one: Absolutely no one: French medical textbook: hey here is a mnemonic to help you remember complications of obesity : "fat sow"

We are happy to share our recent preprint on (first ever CRISPR paper in my life😅): "CRISPR/dCas-mediated counter-silencing – Reprogramming dCas proteins into antagonists of xenogeneic silencers" #CRISPRcosi 🧵(1/8) https://t.co/v8Hg5dG6T8 @fz_juelich, @HHU_de, @MibiNet_1535

It was fun to bring together this special issue as editor with @RobLavigne1! Lucky to be part of a research community "...driven by curiosity and fellowships of phage researchers looking for someone to share in an adventure." https://t.co/BWkxvJ1aIb @SPP2330

Excited to introduce AntiDefenseFinder - a free, open source tool that detects anti-defense systems in any genomic sequence. Available here to toggle on/off: https://t.co/2Z08fGyQLD. Read below for our insights into the >47K detectable systems📈

Really proud to see this work published -- a thrilling detective story I was lucky to be a part of. Big kudos to @stephentang23 and the entire team for an impressive collaborative effort. See Stephen's thread below to learn more... (and read the paper!). https://t.co/EsYtiL68QA

Bitter-sweet result. Our paper is out in Nature, but sometimes you're forced to hide your affiliation to make it happen. Viruses encode tRNAs to circumvent tRNA-targeting immune systems, like PARIS. Thanks to @dbikard, @WiedenheftLab and the teams. https://t.co/uTAdJWjW4f