Aël Hardy
@ael_hardy
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MD-PhD student @MedecineSU @MDMlab_Paris, formerly PhDing @FrunzkeLab 🔬 #phage phan interested in medicine 🇺🇦 #NAFO 🐘 https://t.co/M3Gyb7ZYFk
Paris, France
Joined May 2018
Very happy to change my profile picture to a fella. #NAFO is an amazing way to support Ukraine, in a time where 🇷🇺 relentlessly bombs 🇺🇦 civilians in the most abject way. Check out @Official_NAFO if you're interested to contribute too.🌻.🇺🇦 must & will win this war #СлаваУкраїні
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RT @ben_a_adler: It is finally out! . Muntathar Al-Shimary, Doudna Lab, @bradyfcress and I present a gene knockdown tool that works in div….
nature.com
Nature Microbiology - Leveraging RNA-targeting dCas13d enables selective interference with phage protein translation and facilitates measurement of phage gene fitness at a transcriptome-wide scale.
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RT @clement_molin: We shouldn't be afraid of Russia ☢️🇷🇺☢️. What many failed to understand is that Putin is not crazy nor stupid. He is eve….
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RT @SorekLab: Published today @NatureComms. We discovered a bacterial NLR-like pattern recognition receptor that can sense 3 different vira….
nature.com
Nature Communications - Avs proteins are bacterial anti-phage pattern recognition receptors evolutionarily related to eukaryotic NLRs. Here, Béchon et al show that a single bacterial Avs can...
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RT @SorekLab: Fancy a postdoc in Munich? For a collaborative project between @SorekLab and @hornung_lab on antiviral innate immunity, we ar….
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RT @ben_a_adler: 🦠🧬Our paper is live @CellCellPress: Genome integrity sensing by the broad-spectrum Hachiman antiphage defense complex.http….
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RT @paulnovosad: What kind of childhood makes a top scientist? Is it enough to have all the right traits (brilliance, grit, etc) or do you….
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RT @AHarms485: Exciting and fantastic work - the new peak of recent studies reminding us that viruses are not the only mobile elements with….
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RT @AHarms485: You are looking for a PostDoc position or know someone who is? We are looking for someone to join our team at @ETH_en Zürich….
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RT @United24media: Are you planning to visit Ukraine soon? Or would you like to show your support and learn a little Ukrainian?. Check out….
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RT @MDMlab_Paris: In a new study, we report the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathw….
biorxiv.org
The full extent of immune system conservation between prokaryotes and eukaryotes is unknown. However, recent research supports that a subset of bacterial antiphage proteins is conserved in eukaryotes...
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RT @Matt_Hdqt: Almost two years ago I joined @MDMlab_Paris and @Poirier_Lab to study the conservation of immunity between prokaryotes and e….
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No one:. Absolutely no one:. French medical textbook: hey here is a mnemonic to help you remember complications of obesity : "fat sow"
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RT @FrunzkeLab: We are happy to share our recent preprint on (first ever CRISPR paper in my life😅):. "CRISPR/dCas-mediated counter-silencin….
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RT @FrunzkeLab: It was fun to bring together this special issue as editor with @RobLavigne1!. Lucky to be part of a research community ". ….
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RT @MDMlab_Paris: Excited to introduce AntiDefenseFinder - a free, open source tool that detects anti-defense systems in any genomic sequen….
biorxiv.org
The co-evolution of prokaryotes, phages, and mobile genetic elements (MGEs) over the past billions of years has driven the emergence and diversification of defense and anti-defense systems alike....
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RT @shsternberg: Really proud to see this work published -- a thrilling detective story I was lucky to be a part of. Big kudos to @stephent….
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RT @Artem_Isaev_: Bitter-sweet result. Our paper is out in Nature, but sometimes you're forced to hide your affiliation to make it happen.….
nature.com
Nature - Structural and functional studies reveal how viral proteins trigger the phage antirestriction induced system (PARIS) to degrade host tRNA and how viral tRNAs suppress the PARIS nuclease...
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