Rob Lavigne
@RobLavigne1
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All things bacteria, phage and other viruses. Biology to biotechnology. I actually enjoy teaching too! Hobbies? what are those?
Belgium
Joined July 2013
Thanks @GuelPHage_lab for this interesting collaboration.
A new milestone in our phage research program @AAFC_Canada .Our latest paper is now out #msystems @ASMicrobiology where we dig deeper into the systems biology of phage/host interactions using a multi-omics approach. We studied the P100-like #phage CKA15 infecting #Listeria mono
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RT @AzeredoLab: And now, to discuss the future of phage therapy, we're having a round table with this great panel of experts .
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RT @JessicaSacher: Personalized or one-size-fits-all: the phage therapy field's favorite binary. Or is it a spectrum?. Excited to share ou….
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RT @bollyky: Congrats to @kevin_minyoung and @JessicaSacher on their review of phage therapy production and drug development. It was great….
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RT @PabloINik: Engineering a phi15-based #expression system for stringent #gene expression in #Pseudomonas putida—led by @EvelineLammens, @….
nature.com
Communications Biology - The development of a modular, phage-based expression system optimized for Pseudomonas putida enables stringent, tunable and high yield expressions with minimal cytotoxicity.
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Go beyond #genome #sequencing !.Giant #Pseudomonas #phage #transcription landscape reveals novel #sRNA & regulatory elements. Relevant to phage #biology & #microbiology #SyntheticBiology .#research #Publication in @MicrobialBiote1 .@ERC_Research
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Thank you Karim & team for the fruitfull and efficient collaboration.
Excited to share our article describing the effectiveness of phage HK6 in biocontrolling multidrug-resistant E. cloacae found in food samples. This approach could be a promising strategy to limit the spread of these pathogens in healthcare settings.
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Tools, tools, tools.Check out our #phage #protocols in @springerpub in #Methods in #Molecular #Biology.ONT cappable seq #transcriptome.Mapping:. CRISPR/Cas3 Based lytic phage #genome #Engineering :.
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Wonderful guest editing a special issue in Current Opinion in #Microbiology with the amazing @FrunzkeLab, entitled: Host-Microbe Interactions: #viruses 2024. Check out the 12 amazing contributions and our #Tolkien inspired editorial :.
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And here's our new @UZLeuven standardized bench-to-bedside protocol to assess kinetics and dynamics of #Phagetherapy for #musculoskeletal #infections. #publication in @FrontiersIn.#Cellular and #infection #Microbiology . #PhageForce
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Putting #phage #antibiotic synergy into practice. Co-delivery formulation approach for #MRSA treatment in fracture-related infections . #publication in @Nature_NPJ with @AOFoundation. #FRI #AMR #clinic #microbiology #staphylococcus
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Also out this week: multiparameter #evolution training of #phage to target #Pseudomonas for improved cocktails in #phagetherapy. #publication in @NatureComms with Kunisch etal:. #microbiology #bacteria
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#Pseudomonas #protein PlzR regulators type IV #pili assembly in a c-di-GMP manner by PilZ/B #interaction. Check our #publication in @NatureComms . #microbiology #motility #bacteria #AMR #molecular #biology
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RT @MicrobialBiote1: Microbes are crucial to our planet and well-being but go unnoticed. They provide food, medicines, clean water & help w….
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20y of dedication/perseverance by @PaulPirnay , @mmerabish & team to make #phagetherapy a reality. A good moment to say thank you for our 30th joint publication.
OUT NOW 👉 Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study @PaulPirnay @DjebaraSarah @StevenDeSoir @GlontiTea @JeroenWagemans @PJ_Ceyssens @RobLavigne1 @mmerabish #phage.
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New insights on intricate & diverse #gene #expression regulation mechanisms of different #pseudomonas aeruginosa #phage clades, using our ONT-cappable #sequencing. Proud of this #publication in @microLifeJrnl . #transcription #microbiology #BIONICBACTERIA
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Exploring our views on the impact of Post Translational Modifications elicited by #phage to rapidly finetune #bacteria #metabolism during #infection . Review with @noort_zuit in .Current Opinion in #Microbiology :. #bioinformatics #alphafold #omics
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Systematic strategy to decipher #phage-mediated #bacteria takeover using Grad-seq (gradient fractionation of #protein complexes coupled with #RNAseq & #proteomics) reveals phage #peptide modulating bacterial protein synthesis machinery @NatureMicrobiol : .
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