Anissa Widjaja
@aa_widjaja
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🇲🇨scientist. Assistant Professor @dukenus 🇸🇬. Translational research focusing on ageing, CKD, DKD, and kidney regeneration.
Singapore
Joined July 2009
RT @NatMetabolism: #NatMetabPicks | In @Nature led by @aa_widjaja & @stuartacook1 (@dukenus):. IL-11 is identified as a key regulator of E….
nature.com
Nature - IL-11 is identified as a key regulator of ERK–AMPK–mTORC1 signalling, metabolism, inflammation and age-related disease and lifespan in mouse and human.
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RT @ImmunoPodcast: Forever young? 🐁 . Drs. Anissa Widjaja (@aa_widjaja), @WeiWenLim23, @StuartACook1, and their team found that inhibiting….
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RT @NaturePortfolio: A paper in @Nature reports the ageing effects of a pro-inflammatory protein called IL11 in mice. Inhibition of this pr….
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RT @davidasinclair: A new paper has lit up the longevity field. Removal of interleukin-11 improves health and extends mouse lifespan by up….
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RT @HonkIfUrHoary: My favorite is that in every colony of naked mole rats there are a couple individuals whose job is just to grow as large….
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RT @jenheemstra: On the tougher days in this job, I need to remind myself that:. -the self-doubt means I have ambitious career goals.-the f….
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RT @DanielJDrucker: Studies in mice #aging identify blockade of IL11 actions lowers epigenetic age, reduces telomere attrition, and preserv….
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RT @stuartacook1: In a mouse model of MS therapeutic use of anti-IL11 reduced clinical scores, CNS inflammatory infiltrates, and demyelinat….
pubmed.ncbi.nlm.nih.gov
The objective of this study is to examine IL-11-induced mechanisms of inflammatory cell migration to the central nervous system (CNS). We report that IL-11 is produced at highest frequency by myeloid...
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RT @dukenus: For #WorldKidneyDay, we revisit a groundbreaking discovery by scientists from #DukeNUS who identified the crucial role played….
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RT @agingdoc1: Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease. https://t.co….
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RT @OdedRechavi: Outsiders wouldn't understand the feeling one has during the weeks when you are expecting a decision on a manuscript. You….
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RT @dukenus: We're so proud of Asst Prof Anissa Widjaja and Dr Eugenia Ong, who were featured in the National Research Foundation's RIE mag….
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RT @TanentzapfLab: Most scientists have simple modest wants: a) stable decently paying job b) funding to pursue stuff they are interested i….
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RT @stuartacook1: Kidney regeneration in chronic kidney disease is possible!. Anti-IL11 unleashes endogenous renal repair mechanisms and re….
pubmed.ncbi.nlm.nih.gov
The kidney has large regenerative capacity, but this is compromised when kidney damage is excessive and renal tubular epithelial cells (TECs) undergo SNAI1-driven growth arrest. Here we investigate...
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RT @stuartacook1: Slowing ageing and increasing health-span with anti-IL11 therapy. A 20 min video
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RT @stuartacook1: Brain atrophy in old age. Prevented by giving anti-IL11 to old mice. Probably the craziest and most unexpected result out….
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RT @AdamMGrant: Repeat after me: good communication requires repetition. Data: leaders are 9x more likely to be criticized for undercommun….
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RT @stuartacook1: “Interleukin 11 (IL11) is upregulated in inflammatory conditions, where it is mostly believed to have anti-inflammatory a….
pubmed.ncbi.nlm.nih.gov
Interleukin 11 (IL11) is upregulated in inflammatory conditions, where it is mostly believed to have anti-inflammatory activity. However, recent studies suggest instead that IL11 promotes inflammat...
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RT @stuartacook1: LKB1 (STK11), a master metabolic kinase, is inhibited by IL11. The most direct example of immunometabolism to date @Imm….
cell.com
Cell biology; Functional aspects of cell biology
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