Wei Tao
@WeiTaoLab
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Farokhzad Family Distinguished Chair (Endowed Chair) @BrighamWomens | Associate Professor @Harvardmed | Member of Academia Europaea (MAE) | AIMBE Fellow
Boston, MA
Joined April 2019
Thanks @NatureMedicine for this interview, and I am glad that the Drug Delivery Technologies developed in my lab can be highlighted. It is also my great honor to be alongside world's top scientists - Profs. Bob Langer, @SMitragotri, @ryanfdonnelly, etc. https://t.co/kKMHociFmk
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This integrative approach represents a notable advance in LNP characterization, offering a more mechanistic understanding of how structural and biophysical attributes influence functional performance. - Another fantastic work by @MJMitchell_Lab and his team! @NatureBiotech
Research Briefing: Solution biophysics reveals the polydisperse structure of RNA lipid nanoparticles https://t.co/BpyiKnNvxF
https://t.co/c8RiMnLVG3
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New in @NatureNano: Systemic delivery of IL-10-mRNA NPs triggers strong immune surveillance in diverse tumor models. This #mRNA NP strategy may offer promise for overcoming recombinant IL-10's challenges in immunosuppressive tumors. https://t.co/n0e02L6qBS
nature.com
Nature Nanotechnology - Intravenous interleukin-10 messenger RNA nanoparticles enhance immune responses in preclinical tumour models, promoting T cell activity and dendritic cell maturation, as...
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RNACap can orally deliver liquid mRNA therapeutics to the intestines in response to intestinal pH, the resulting pressure release, and contractions https://t.co/bQdyg0VYDQ
@ScienceTM
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The new issue of #ScienceTranslationalMedicine has arrived! Engineered capsules can deliver liquid mRNA therapeutics to treat intestinal disease in animals, the complement cascade offers a target in acute chest syndrome in sickle cell disease, and more. https://t.co/NELkknKnH9
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By loading different types of mRNAs, new oral mRNA vaccines for infectious diseases and oral mRNA medicines for cancers are possible. This technology could also benefit the oral delivery of other types of biologics (e.g., nucleic acids and proteins) to tackle different diseases.
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Our new paper is published as a Cover Story -"Eating the Message" in @ScienceTM. This paper demonstrates that oral mRNA delivery to the intestines is feasible using our RNACap design. Congrats to our Rising Star @XiangangHuang and the team!
Engineered “RNACaps” provide oral delivery of liquid #mRNA therapeutics to the intestines in small and large animals for the treatment of #colitis and could support the clinical translation of oral mRNA therapies. @WeiTaoLab @BrighamAnes @XiangangHuang
https://t.co/SjKazC1QdZ
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New Issue Online👏 | Volume 6 Issue 6🥳 check👉 https://t.co/oy2UFpcsKC
@BenZhongTANG1 @yuning_hong @NusXie @shrikezhang @mcgonigalgroup @Alc_Rimbaud @RivardGroupUofA @WeiTaoLab @akyetisen
onlinelibrary.wiley.com
Aggregate is an open access aggregate science journal for research involving the assembly of structures - from cell & protein aggregation to aggregate materials.
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Happy to share our most recent article on using RNA therapeutics to promote healthy aging @NatureAging. Congrats to Shuying and Qian from my team. Link here: https://t.co/HywyjJyD8a
Online now! ✨Chen et al review RNA therapies targeting mechanisms of aging and age-related diseases https://t.co/pBqTdKWEps
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The Tao Lab currently has one postdoc position opening. More information can be found on the page below: https://t.co/ZncAygLbCK
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Modulating nano-bio interface via drug-framework hybridization to activate chemoimmunotherapy against glioma postoperative recurrence https://t.co/UVhiGVnoLm
#biomaterials #bioengineering
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Happy to see our invited Perspective on "Live bacterial chemistry in biomedicine" online @Chem_CP Congrats to Senfeng and Qimanguli in my team @BrighamWomens @harvardmed
https://t.co/8bjoVzMDxB Free access here:
cell.com
This perspective summarizes the programmable chemical sites on live bacteria and the potential physical, chemical, or biological functions achievable through chemical engineering strategies, highli...
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Honored to be inducted as a Fellow into the American Institute for Medical and Biological Engineering @aimbe @BrighamWomens @harvardmed! Many thanks to my nominator, who is my real role model in many aspects! (Thanks to my friends for taking nice photos from different angles📸)
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Happy to see our most recent paper entitled "Lactate‐Modulating Nanozyme‐Mediated Mitochondrial Respiration Block for Tumor Immunosuppression Remodeling" published in @angew_chem. Congrats to Senfeng!
onlinelibrary.wiley.com
The carbon-dopped copper nitride (Cu3N−C) acts as a lactate oxidase-mimicking nanozyme. C doping enhances n−σ* delocalization of the oxygen lone pair from lactate C−OH bond, weakening hydroxyalkyl...
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My honor to receive this year's award from @Biomaterials_.
Biomaterials is pleased to announce 2025 winners of "Biomaterials Global Impact Award" (Andrés García @GarciaLabGT) + Biomaterials Award for Young Investigator (Jinah Jang @JinahJang4 & Wei Tao @WeiTaoLab). Award ceremony will be @EuTermis '25. CONGRATS!!🎉 https://t.co/LExF2VAcnI
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@WeiTaoLab is invited and will deliver a talk on Drug Delivery Technologies @Materials_MRS 2024 Fall Meeting. We are also on the way to translating our technologies into clinical use.
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Congrats to @YJLi_us and @WeiChen_CW. Free access can be found here:
Wei Tao and colleagues review nanobiomaterials-based strategies that modulate inflammatory responses in #MatterIssue65! Read more: https://t.co/dhNM0wwFbs
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Great work led by @WeiChen_CW @ZhuomingZhou!
Excited to share our most recent work regarding "Nanomedicine-based strategies for the treatment of vein graft disease" in @NatRevCardiol from the @WeiTaoLab The paper can be downloaded via https://t.co/r4QHvu7lJD
@ZhuomingZhou @harvardmed @BrighamResearch
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