Tolga Bozkurt
@Tolga_Bzkrt
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Scientist @ Imperial College London, working on plant immunity, autophagy and immune receptor trafficking. https://t.co/8qFb7bRjOV
London
Joined July 2014
Our new preprint, in collaboration with @KamounLab and contributions from @jonathandgjones, @AdamWu9527, and @JiorgosKourelis labs, on the exciting discovery of organelle targeting by an activated helper NLR is out! 👇
🚨 A new twist in #NLRbiology! 🚨 Excited to report on the surprising mechanism where the helper NLR NRG1 targets organellar membranes to trigger immunity unlike canonical CC-NLRs, which function at the plasma membrane! 1/11 🧵 https://t.co/jqIquRcz9D
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Please RT‼️ #TenureTrack position @ZmbhH - one of the best #proteostasis research centres in the world.
nature.com
The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a Tenure Track Professors...
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The unspoken rule: Immigrants are welcomed only when they’re ‘useful’ and compliant. The moment they question authority, they are disgraceful — no matter how much they contribute.
bbc.com
Liverpool forward Mohamed Salah is called a "disgrace" who has caused "carnage" at the club by pundits as the fallout continues from his explosive interview.
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My department is seeking an Assistant Professor of Horticulture. We'll start reviewing applications on December 19. Join a fantastic group of colleagues! https://t.co/qJcd95U0Bi
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Exciting new paper on aging: 1. CRISPR-mediated DNA breaks cause heritable epigenetic changes 2. Changes occur genome-wide, not just at breaks 3. Natural DNA breaks also disrupt the epigenome Strongly supports The Information Theory of Aging (ITOA) https://t.co/Vw4veR0JV3
link.springer.com
Genome Biology - CRISPR-Cas9 genome editing enables precise genetic modifications by introducing targeted DNA double-strand breaks (DSBs). While Cas9-induced DSBs are known to cause unintended...
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🚨Today @CellCellPress: @YaqiuWang, @ThiruKanneganti, & team identified a new #celldeath pathway, mitoxyperilysis! Innate immune & metabolic synergy --> damaged #mitochondria staying at the membrane --> local oxidative damage & cell bursting. Check it out! https://t.co/7yq5XqzvSV
cell.com
Wang et al. identify a new lytic cell death pathway, mitoxyperilysis, triggered by the synergy of innate immune activation and metabolic stress. This process is regulated by mTORC2 and involves...
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Gemini 3 Deep Think is here. Deep Think is our most advanced reasoning mode that explores multiple hypotheses simultaneously to give you an even more sophisticated output.
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Scientists have no time for peer reviews. So, real AI Reviewers are taking over. OpenRxiv is integrating an AI reviewing tool to get 30-min feedback on biomed manuscripts (Nature News describes it in detail). AI Reviewers give advantages (my view): - No more Reviewer # 2. This
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How can the same "master regulatory" protein mTOR recognize different sets of targets to separate nutrient and growth factor signals? Thrilled to share our new paper, in which we reveal how mTORC2 recognizes Akt. 🧵 on our new paper in Science: https://t.co/PSZWMsEYbn
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We present evidence of a gene duplication event 28–18 million years ago that coincided with the global expansion of C4 grasses, allowing the maize pathogen #Colletotrichum graminicola to evolve CgEP4—a novel, nuclear-targeting #effector weapon.
biorxiv.org
Colletotrichum species rank among the most important fungal pathogens, threatening food security by infecting nearly all major crops worldwide. Colletotrichum graminicola , the causal agent of maize...
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Are you interested in #evolution of #receptor networks, selective #autophagy or #proteostasis, please have a look at our new story: https://t.co/wAZboUk0Ea
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This is insane 🤯 A new system called Paper2Video can read a scientific paper and automatically create a full presentation video slides, narration, subtitles, even a talking head of the author. It’s called PaperTalker, and it beat human-made videos in comprehension tests.
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🩺 Canadian Scientists Build a Rice-Sized Robot That Breaks Kidney Stones — With Almost No Pain Canadian researchers have developed a tiny magnetic robot—no bigger than a grain of rice—that can travel inside the body and break kidney stones safely, gently, and without surgery.
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Our new paper is out! Autophagy acts as a gatekeeper of plant–fungal symbiosis. Zecua and Dunken et al. show how Arabidopsis restricts endophyte over-colonization and symbiosis-induced cell death to keep the partnership beneficial.
academic.oup.com
Autophagy acts as a pro-survival mechanism in plant roots during beneficial fungal colonization by restricting fungal proliferation and immunometabolic cel
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We're now rolling out interactive images to the @GeminiApp for more visual and dynamic learning. It’s designed to help you visually explore complex academic concepts, turning studying from passive viewing into active exploration. Learn more → https://t.co/GLVkfBIuGd
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Cancer cells steal mitochondria from neurons to spread throughout the body.
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Google has integrated Google Scholar with AI. Run a search and it will screen the 10 most relevant papers and shows how the paper answer your question. This will make literature discovery very efficient. Here's how to use it:
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STOP TELLING CHATGPT TO "MAKE A PRESENTATION FOR ME" Bad prompt = Bad result. Use these prompts instead and see the magic:
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Releasing a new "Agentic Reviewer" for research papers. I started coding this as a weekend project, and @jyx_su made it much better. I was inspired by a student who had a paper rejected 6 times over 3 years. Their feedback loop -- waiting ~6 months for feedback each time -- was
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Ultra-processed foods now make up at least half of all food sold in UK supermarkets. The Lancet has described them as a “corporate-engineered public health crisis.” That is exactly what they are: industrial products designed for profit, not nutrition. They override appetite
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