Tolga Bozkurt
@Tolga_Bzkrt
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Scientist @ Imperial College London, working on plant immunity, autophagy and immune receptor trafficking. https://t.co/8qFb7bRjOV
London
Joined July 2014
Our new preprint, in collaboration with @KamounLab and contributions from @jonathandgjones, @AdamWu9527, and @JiorgosKourelis labs, on the exciting discovery of organelle targeting by an activated helper NLR is out! 👇.
🚨 A new twist in #NLRbiology! 🚨. Excited to report on the surprising mechanism where the helper NLR NRG1 targets organellar membranes to trigger immunity unlike canonical CC-NLRs, which function at the plasma membrane!. 1/11 🧵.
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RT @VT_TPSC: Former students and colleagues of Dr. John McDowell published a @MPMIjournal article detailing John's amazing scientific achie….
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RT @KamounLab: #HeardToday #AcademicChatter. I'm reviewing this paper while on holiday at the beach, which normally puts me in a positive m….
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RT @Freddie_King00: I finally got around to publishing my MPMI poster on 'Developing broad bean as a new model system for studying plant im….
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RT @wenboEffector: Excited to preprint work mainly by former postdocs Li Feng, Yingnan Hou @Cerhou, and the phylogenomics genius @amiralito….
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RT @TerezaYan: First Ma lab #GMI paper is now online! It‘s a mini-review on insect-induced plant #galls —their coolness and research potent….
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RT @HuckelhovenR: Finally published. A big thank you to all contributors: Barley resistance and susceptibility to fungal cell entry involve….
onlinelibrary.wiley.com
The ROP GTPase RACB has been co-immunoprecipitated with two host phospholipid-metabolizing enzymes and one fungal effector that influences pathogen interaction. All three modeled protein complexes...
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RT @NewPhyt: Can AI structural modelling distinguish between sensor and helper NLR immune receptors?. Toghani et al. @amiralito_ @Tolga_Bz….
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RT @NikoMcCarty: In 2007, physicist Freeman Dyson wrote an essay called “Our Biotech Future” for The New York Review. In it, he wrote:. “I….
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RT @avi_cmbi: 📢 paper - a new class of RIPK1 inhibitors. Lots of with here, with structure of it bound to RIPK1, biochemistry and more! Was….
pubs.acs.org
Necroptosis is a form of programmed cell death that, when dysregulated, is associated with cancer and inflammatory and neurodegenerative diseases. Here, starting from hits identified from a phenoty...
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RT @dromius: #2025ISMPMI - first new to nature chimeric NLR sensors being created, with integrated domains that do not have sequence or str….
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RT @nutthalak: #2025ISMPMI Excited to share insights from my postdoc work at @TheSainsburyLab on NLR diversity and evolution in Caryophylla….
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RT @YuSugiharaY: 🎉 Exciting news during #2025ISMPMI .Our AlphaFold 3 sensor vs helper NLR paper is now published in @NewPhyt!. Big thanks t….
nph.onlinelibrary.wiley.com
Click on the article title to read more.
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RT @SaskiaHogenhout: Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies | Science Advances https:….
science.org
Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.
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Fasniating discovery by Suomeng Dong and his colleagues about a the first ever TIR NLR resistance gene against Irish potato famine pathogen P. infestans.
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RT @mpcontreras4: #ISMPMI2025 check out this beautiful #cryoEM structure! A pathogen L-shaped effector blocks resistosome assembly of a hel….
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RT @SaskiaHogenhout: Effector Innovation in Genome-Reduced Phytoplasmas and Other Host-Dependent Mollicutes | bioRxiv .
biorxiv.org
Obligate host-associated bacteria with reduced genomes, such as phytoplasmas, face strong evolutionary constraints, including metabolic dependence on hosts, limited horizontal gene transfer (HGT),...
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RT @JMadhuprakash: 🚨New @biorxivpreprint alert! .We are thrilled to share our latest findings—building on our earlier work on suppressors o….
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RT @forallcurious: You are looking at the first ever image of another multi-planet solar system
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