Ashley St. John Lab
@StJohnLab
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St. John lab @DukeNUS studies immune responses to human pathogens and develops novel vaccination strategies. We love mast cells. Tweets by Ashley.
Joined February 2018
Did you know that the fetal immune system can protect from congenital infection before birth? -Proud to share our study identifying protective functions of #microglia, contrasting the harmful early influence of #monocytes and primitive macrophages to #zika virus infection.
Now online! Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection
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Thank you @StJohnLab for inviting me for the @HcvFlavi2025 So lovely to meet up with you again. Its been one of the best conferences. Congratulations for putting together such a wonderful meeting. #dengue #flavi
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Very inspired that Yaghi, a Palestinian refugee who came to the U.S. at 15 received the 2025 chemistry #NobelPrize . A reminder of the power of education to unleash talent, a testament to U.S. capacity to attract/ enable talent, and how much progress a we lose to incessant wars
This year’s chemistry laureate Omar Yaghi was born in Amman, Jordan, in 1965 to parents who were refugees from Palestine. When we spoke to him he shared his story: “I grew up in a very humble home, we were a dozen of us in one room, sharing it with the cattle that we used to
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Delighted to see Chia-Lin featured by @JExpMed - one of the #womeninSTEM I’ve always admired.
👩🔬 JEM invited NYCU’s Prof. Chia-Lin Hsu to share her journey as a female scientist—founding a lab, chasing dreams, and overcoming challenges. A voice from Taiwan to empower more women in science. 💡 #WomenInSTEM #WomenInScience #NYCU #JEM #TaiwanScience
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The Granulocyte Meeting 2025 has officially concluded! 🙏 Huge thanks to all the incredible speakers & chairs, your contributions made this meeting a success. 📍 Looking ahead: see you all at #GMeeting2027 in Korea! #GMeeting2025
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“I was fired for holding the line on scientific integrity. The stakes are not theoretical — we have already seen the largest [US] measles outbreak in more than 30 years, which claimed the lives of two children.” https://t.co/Npitw2ncG8
nature.com
Nature - Susan Monarez testifies at tense Senate hearing that scientific integrity is being quashed at US health agency.
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Bittersweet ending to the second Granulocyte Meeting! Thank you @lai9uan for bringing us to Shanghai for another chance to unite the granulocytes. Next stop Korea 2027!
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Interested in attending the EMBO Lecture Course, entitled "RNA virus infection and host immune responses," hosted in Faridabad, India, on 11 – 14 February 2026? sign up here: https://t.co/Byw2hhNvND
meetings.embo.org
The India I EMBO Lecture Course on “RNA virus infection and host immune responses” addresses cutting-edge research in emerging and reemerging RNA viruses, with particular emphasis on fundamental infe…
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A new analysis of a cohort in Nepal links the waning of vaccine immunity against Japanese encephalitis virus to elevated chymase levels and a higher risk of severe #dengue infection. Read more in @ScienceTM: https://t.co/HMAZlYMhaL
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A new analysis of a cohort in Nepal links the waning of vaccine immunity against Japanese encephalitis virus to elevated chymase levels and a higher risk of severe #dengue infection. Read more in @ScienceTM: https://t.co/HMAZlYMhaL
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A new analysis of a cohort in Nepal links the waning of vaccine immunity against Japanese encephalitis virus to elevated chymase levels and a higher risk of severe #dengue infection. @StJohnLab @dukenus @smlhtr_
https://t.co/iuI3V1aiu5
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Dengue is rising. In Nepal, studying >500 #dengue patients, we found that waning immunity to Japanese encephalitis virus (#JEV) was associated with worsened dengue severity, which has implications for #vaccine campaign planning. First au🙌: @smlhtr_
https://t.co/tdR7MMF0gg
science.org
Waning immunity to Japanese encephalitis virus was associated with increased severity of dengue disease in a cohort of patients from Nepal.
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Thank YOU for inviting me to a fabulous meeting!
A big thank you to Ashley St John @StJohnLab from Duke-NUS Medical School for kicking off our 2025 Vic/Tas Branch Meeting at the beautiful Melbourne Zoo, with an engaging talk on how the fetal immune system controls congenital viral infections! 🐅🐘🌿
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Excited to share our new #OpenAccess review: "Maternal IgE Influence on Fetal and Infant Health" led by Jozef. We discuss how maternal #IgE shapes fetal immunity and the shift to intrinsic early-life IgE production, with implications for #allergy onset. 👉 https://t.co/0hyAOLdRQB
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Little break from talks to visit Knossos Palace… finally spending time with @Zhijuan_JExpMed not on zoom!
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https://t.co/uCddNwmhuC So excited to share our work on placental changes across gestation. Activation of immune cells types in term placentas even before labor and a reduction in toleragenic cells. Congrats @BunmiOlaloye et al. @YalePediatrics @YaleMed
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Happy to share our preprint assessing the body composition, in a South Asian population. Adiposity and lean muscle indices that associate with cardiometabolic risk factors and inflammatory mediators in a South Asian population https://t.co/QCca12N7ql
@chandi2012 @dumni
medrxiv.org
Background Cardiovascular diseases (CVD) are the leading cause of death in South Asia with visceral adiposity and sarcopenic obesity emerging as critical risk factors. Methods We conducted a cross-...
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Very proud moment 😊- the 1st paper of our lab has just been published: https://t.co/h8q5tLHF5M This tour-de-force work was bravely headed by the fantastic @MaryemRadhouani, showing that #Eosinophils develop #InnateMemory upon skin #infection with implications for lung #allergy
science.org
Staphylococcus aureus skin infection induces eosinophil innate immune memory to exacerbate allergen-induced airway inflammation.
I'm excited to share that my first-author PhD paper is now published in @SciImmunology! We showed that skin infection with S. aureus imprints bone marrow eosinophils to fuel lung allergy. 🔗link to the study: https://t.co/WoRNMp6mrX Let’s dive in 🧵1/9
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Awesome Power of Genetic Screening! Very honored to be part of this wonderful discovery—MFSD6 is an entry receptor for Enterovirus D68!
🚨 New paper in Nature! MFSD6 is an entry receptor for enterovirus D68. Proud to have contributed to this work, led by brilliant co-first authors Lauren Varanese & Lily Xu. Gratitude to Jan Carette, Wah Chiu, and co-authors including Carolyn Bertozzi. 👉
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📢 Delighted to introduce the 2025 Associate Editorial Board: @Casanova_Acebes @CNIOStopCancer, @DGateLab @ARC_Neuro, Elisa Oricchio @EPFL_en, Tim O’Sullivan @UCLA, Ashley St. John @StJohnLab @DukeNUS, and Tuoqi Wu @UTSWMedCenter. Welcome! 👉 https://t.co/7ATvFp3nHD
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Save the date for #HCVFlavi2025, a joint Asia-Pacific meeting to be held October 13-16, 2025 in Singapore @dukenus! More info to come!
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