Sidharth Malhotra
@smlhtr_
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MD-PhD Candidate at Duke-NUS Medical School
Singapore
Joined May 2021
A new analysis of a cohort in Nepal links the waning of vaccine immunity against Japanese encephalitis virus to elevated chymase levels and a higher risk of severe #dengue infection. Read more in @ScienceTM: https://t.co/HMAZlYMhaL
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Dengue is rising. In Nepal, studying >500 #dengue patients, we found that waning immunity to Japanese encephalitis virus (#JEV) was associated with worsened dengue severity, which has implications for #vaccine campaign planning. First au🙌: @smlhtr_
https://t.co/tdR7MMF0gg
science.org
Waning immunity to Japanese encephalitis virus was associated with increased severity of dengue disease in a cohort of patients from Nepal.
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You may think that neurological symptoms in #LongCovid are for old people, but it is the opposite. Young adults (18–44 years) and middle-aged (45–64 years) with mild acute #COVID cases (non-hospitalized) represent 90% of the cases of #NeuroCovid Read here: https://t.co/qd2NMH8LrF
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Well it's another study that comes like a kick in the gut. Covid infection in pregnant mothers disrupts immune balance, alters fetal brain cells and increases offspring's risk of neurodevelopmental disorders. In Nature: https://t.co/BmVYF3zp8A
nature.com
Molecular Psychiatry - Maternal COVID-19 infection associated with offspring neurodevelopmental disorders
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⚠️ BREAKING: Canada 🇨🇦 reports its first human case of H5 bird flu in a teenager in British Columbia. The case is hospitalized and contact tracing and source investigation is ongoing, according to the B.C. Government.
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Did you know that the fetal immune system can protect from congenital infection before birth? -Proud to share our study identifying protective functions of #microglia, contrasting the harmful early influence of #monocytes and primitive macrophages to #zika virus infection.
Now online! Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection
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Introducing ✨Dr✨Sid Malhotra who defended his thesis today! 🍾 He’s made it past another step on the path to be a clinician scientist! He’s also a @SD_GHI Doctoral Scholar and plans to continue his #globalhealth projects before returning to med school. @smlhtr_
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Wrapping up a great visit to Sri Lanka introducing Sid to the @RDCIDRuhuna site. He’ll be working there with Dilshan (left) & team to wrap up our project on COVID/dengue biomarkers for the next month & teaching techniques! Thanks to @SD_GHI for making it possible! #GlobalHealth
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It was great to host Dr. Richard @niyiotolorin to advance our collaboration on dengue in Nigeria. After a busy 3 weeks of experiments, here he is with Sid looking like they are going to an awards show.
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Reminder: The reason our health system is collapsing isn’t that there are a lack of beds, but rather, because there are a lack of health workers to staff those beds. Trust us health workers when we say that our health system is not collapsing because of a lack of furniture.
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Do your part and get your booster shot as soon as you can. Find out how, when, and where you can get that taken care of: https://t.co/8iBPRTN5fX
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Bizarre. Singapore screens aggressively for SARS-CoV-2 infection, even among those asymptomatic. Physical distancing and mask wearing are still absolutely required. What is unknown, @CDCgov? https://t.co/wOHetGX8V8
straitstimes.com
Singapore now joins the same classification category as Afghanistan, North Korea and Syria. Read more at straitstimes.com. Read more at straitstimes.com.
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I believe it is time to give in soon. Vaccine protection rates are as high as they may ever be in many places, and now we've got a couple of decent drugs. Pretending we remain in control, of sorts, is just becoming too costly. 5/
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Looking forward to talking in the #globalimmuno series this spring! Check out their new flyer and full speaker line up for 2022:
We are delighted to announce the 2022 #globalimmuno talks organizers: Burkhard Becher @BecherLab Kate Fitzgerald @FitzgeraldKate Florent Ginhoux @FGinhoux Matteo Iannacone @iannaconelab Susan Kaech @Tcellogic Laura Mackay @LMackayLab & the superb program they put together👇
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Is the official Omicron paranoia overblown? Frustration, fatigue have overtaken fear of 'doomsday' warnings
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*shouts* CANADA HAS THE LONGEST LOCKDOWNS BECAUSE IT HAS THE MOST INFLEXIBLE MODEL OF HEALTHCARE DELIVERY.
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Saddened to read that SG is considering booster shots for young adults. More than half the world has no access to vaccines. This is not science.
straitstimes.com
The new measures are aimed at buying Singapore time to get more people vaccinated, and slow down transmission. Read more at straitstimes.com. Read more at straitstimes.com.
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