
Wellcome Sanger Institute
@sangerinstitute
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We are a world leader in genomics research. We apply and explore genomic technologies to advance the understanding of biology and improve health 🧬
Wellcome Genome Campus, Cambs
Joined April 2009
What’s happening with the Chikungunya outbreak in China?. Get the facts in our latest explainer featuring Roger Hewson, a seasoned virologist working at the intersection of science and global public health ⤵️.
sangerinstitute.blog
An outbreak of a rare mosquito-borne virus in Southern China has prompted drastic containment strategies and sparked fears of another pandemic. To understand more about the situation, we spoke with...
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This study with @uk_biobank will deepen our understanding of the human genome, support the development of more effective treatments, and pave the way for precision medicine🧬. Learn more about our journey with UK Biobank here:
sangerinstitute.blog
In 2019, the Sanger Institute started on the most ambitious human genome sequencing project in the world. Three years later, the Institute has delivered nearly 250,000 whole human genome sequences...
✅ Published in @Nature today, the paper describing the initial whole-genome sequencing analysis of 500,000 UK Biobank participants.
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Read ‘Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation’ from @SangerInstitute, @Cambridge_Uni and @u_ikiam in @PNASNews, here ⤵️.
pnas.org
A central question in evolutionary biology is what drives the diversification of lineages. Rapid, recent radiations are ideal systems for this ques...
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Read ‘Genetics, energetics, and allostery in proteins with randomized cores and surface’ from .@sangerinstitute and @CRGenomica in @ScienceMagazine, here 👇.
science.org
A lack of systematic experimental data limits our understanding of protein evolution. In this study, we experimentally characterized proteins with randomized sequences. Vast numbers of amino acid...
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This work is an international collaboration involving scientists in Argentina, Brazil, Chile, Colombia, Mexico, Peru, Uruguay, and the UK. It includes funding from @sangerinstitute @OpenTargets @cziscience @PacBio. Spanish-language site for Project JAGUAR:
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Genomic studies often lack data from Latin American populations, but Project JAGUAR is changing that💪 . “We are laying the foundations for long-term change – in both data and how science is done” @GosiaTrynka, @PJaguarLATAM. More⬇️.
sangerinstitute.blog
Genomic research is lacking representative data, which limits our ability to understand diseases and develop treatments. To fix this, we need to prioritise local leadership, capacity building, and...
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Are you taking part in the #BigButterflyCount this year, or are you a butterfly fan all year round?. Our latest blog dives into the DNA of butterflies and moths seen and sequenced here on Campus. Learn some fun facts about these colourful creatures ⤵️.
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Experts are one step closer to harnessing the power of quantum computing for the benefit of human health 🧬.A Sanger Institute collaboration has progressed to the final stage of the Q4Bio challenge, a @WellcomeLeap competitive research programme👇.
sanger.ac.uk
Sanger Institute team aims to demonstrate the potential of quantum computing in solving critical health challenges.
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There is a stark lack of representation across #genomic science. To address this, we have launched an organisational Representative Research Strategy. Find out what that means in our latest blog:
sangerinstitute.blog
Representation in research is key to ensure that science can benefit all of us. The Wellcome Sanger Institute is one of the first research institutions in the UK to launch an organisational Represe...
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Read ‘The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability across multiple tumor types.’ from @sangerinstitute and collaborators in @NatureGenet, here ⤵️.
nature.com
Nature Genetics - This study employs a functional genomic approach to identify a synthetic lethal interaction between CDS1 and CDS2 in uveal melanoma and other cancers, which may represent a...
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Read 'The long-term effects of chemotherapy on normal blood cells’ from @sangerinstitute, @Cambridge_Uni @CUH_NHS @CancerGrand & others in @NatureGenet ⤵️.
nature.com
Nature Genetics - Mutational signature analysis of blood cells isolated from 23 chemotherapy-exposed samples and 9 nonexposed controls characterizes the effects of various drugs on mutational...
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