Sameer Sheth
@SameerShethMD
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Neurosurgeon @BCMNeurosurgery @BCMHouston @StLukesHealthTX Baylor St. Luke's #Neurosurgery #Neurology #Neuroscience #DeepBrainStimulation #Epilepsy #OCD
Houston, TX
Joined January 2020
📆 Join us for a special #WorldSpineDay webinar on Thursday, Oct. 16 at 12pm CST 📆 @bcmhouston and #BCMNeurosurgery spine expert Dr. Cyrus King discusses managing back and neck pain and prepping for your visit at the #BCMSpineCenter. Register: https://t.co/kPR5VXfLOI 💻
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@SameerShethMD @neurojosh 7/7 Waves in the anterior insula travelled from the anterior towards the posterior insula and got suppressed during successful, compared to, unsuccessful memory encoding, again suggesting heterogeneous dynamics in the insula to initiate efficient dynamic switching and control.
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@SameerShethMD @neurojosh 6/7 Wave strength in the anterior insula was suppressed compared to the posterior insula, suggesting that the anterior insula is a spatially heterogeneous brain area ideally suited for initiating dynamic switching and exerting control over the DMN and FPN.
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@SameerShethMD @neurojosh 5/7 At the group level, wave strength increased for successful, compared to, unsuccessful memory encoding in the beta band. The reverse was true in the theta band.
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@SameerShethMD @neurojosh 4/7 Insular waves also modulate memory performance. For example, a clockwise spiral during memory encoding success, and a counter-clockwise spiral during memory encoding failure. Source waves during successful memory retrieval, and sinks during unsuccessful memory retrieval.
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@SameerShethMD @neurojosh 3/7 Deep learning can decode memory behavior at the single-trial level from these insular waves.
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@SameerShethMD @neurojosh 2/7 We combined iEEG signals across multiple depth probes by using a spatially localized clustering algorithm. We found complex, heterogeneous spatial patterns of insular waves, including spirals, that correlated with behavior, by changing their direction and strength.
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New preprint on the role of insular traveling waves in memory and behavior, using depth recordings from neurosurgical patients, with Chengyuan Wu, @SameerShethMD, and @neurojosh. https://t.co/snnhnt1uEH
biorxiv.org
The insula is a critical brain region that plays a foundational role in adaptive human behaviors, with diverse subregions performing distinct functional roles. However, explaining how these insular...
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Very proud of our group's newest faculty member @NicoleProvenza for her fantastic score that enabled this award despite the recent funding challenges. This work will fuel translational science to help many people suffering with OCD and depression. Congratulations!!
I’m very excited to share that I got the NOA for my first R01 to study approach-avoidance behaviors after DBS for OCD! 🧠⚡️We have an awesome team: @SameerShethMD, Wayne Goodman, Eric Storch, and Ben Hayden at BCM, and Han Yi at JHU APL. @BCMFromtheLabs @JHUAPL
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New preprint from the team, “Attention is all you need (in the brain): semantic contextualization in human hippocampus” . Could not have done it without @SameerShethMD and Ben Hayden! https://t.co/pKgZ8JgMws
biorxiv.org
In natural language, word meanings are contextualized, that is, modified by meanings of nearby words. Inspired by self-attention mechanisms in transformer-based large language models (LLMs), we...
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Huge congrats to Vigi on this award! The Academy Award is the highest scientific honor available to neurosurgery residents. See the preprint here:
biorxiv.org
Consciousness is a fundamental component of cognition,[1][1] but the degree to which higher-order perception relies on it remains disputed.[2][2],[3][3] Here we demonstrate the persistence of...
Dr. Vigi Katlowitz has received the Academy Award for Best Manuscript from the American Academy of Neurological Surgeons for his paper, "Learning and language in the unconscious human hippocampus." Congrats to Dr. Katlowitz, as well as mentors @SameerShethMD & Dr. Ben Hayden! đź‘Ź
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I am honored to have had a chance to speak at the @AANmember about how we hope to improve the way we develop new brain therapies and diagnostics. It was also great to have a chance to highlight collaborators at BCM and MD Anderson working on clinical applications of FUS-BBBO.
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It was a great morning at #BCMNeurosurgery as faculty, residents and students welcomed Dr. Shenandoah Robinson, professor of neurological surgery, neurology and pediatrics at @HopkinsNsurg, as our 11th Annual Raymond Sawaya Lecturer!
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Very proud of my lab alumni who matched today! Huy Dang @HtxDang matched Neurosurgery @UofR, Sandy Reddy matched Radiology @ucdavis, and @Ajay_GandhiMD matched Neurosurgery @UTSWNeurosurg. Many congrats! #Match2025
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Researchers at @bcmneurosurgery identified a new type of cell in glioma, the most lethal form of #BrainCancer. This groundbreaking discovery could reshape prognosis and enhance survival outcomes. @bcmhouston #NeuroTwitter
https://t.co/Ob4Qr9GFW8
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I am incredibly proud to share my first, first-author paper as a postdoc with Ben Hayden. How does the human hippocampus, known for encoding concepts, represent the meanings of words while listening to narrative speech? https://t.co/4mOU2lL9FK
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Support quality health care by nominating Baylor St. Luke’s for U.S. News & World Report's #neurology and #neurosurgery rankings! Help us continue to advance #neuroscience by nominating @bcmneurosurgery on Doximity: https://t.co/CEx11Ta2xA
@bcmhouston @StLukesHealthMD #MedTwitter
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In honor of #ValentinesDay tomorrow, we're sharing this special #ThrowbackThursday ❤️️ Meet Allison and Steven, a husband-and-wife duo who underwent #DBS for #Parkinsons disease, performed by #BCMNeurosurgery's and @StLukesHealthTX's own @SameerShethMD: https://t.co/DPTRbBHFUS
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(1/3) Excited to share our latest health economic analysis in @TheJNS, highlighting the cost-effectiveness of #DBS for refractory #OCD compared to treatment as usual. https://t.co/i5Tq8t2vjk
thejns.org
OBJECTIVE Deep brain stimulation (DBS) is an effective neurosurgical option for patients with treatment-resistant obsessive-compulsive disorder (OCD). Despite being more costly than neuroablative...
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Got an email announcing cancellation of Jan 31 NIH BRAIN Multi-Council Working Group and then got forwarded this. Have to believe it will pass.
science.org
Researchers facing “a lot of uncertainty, fear, and panic”
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