Tremendously honored by 2 recent developments: promotion to Professor
@BCMNeurosurgery
and being named director of the Cain Pediatric Neurology Research Labs
@TCHResearchNews
, dedicated to reducing the burden of childhood epilepsies.
Tremendously honored to be named Cullen Foundation Endowed Chair by
@bcmhouston
. The Cullen Foundation has been supporting health care, higher ed, and performing arts in Houston since 1947. Humbled to be associated with their legacy.
@BCMNeurosurgery
.
Major health insurer Anthem recently announced that DBS of the "striatal axis" is "medical necessary" for pts with OCD who meet (well-accepted) criteria: . HUGE win for pts with severe OCD given otherwise restricted access to DBS despite FDA HDE.
So this is happening! I’m taking a sabbatical to start a minimally invasive bioelectronics company:
@motifneuro
We plan to demonstrate the smallest, least invasive neural interface in humans by the end of 2024. Wish us luck! 🤞 🧠
Great piece in
@ScienceMagazine
on current state of the art in DBS for depression mentioning several recent studies including ours just out today in
@BiologicalPsyc1
using intracranial recordings to optimize DBS therapy.
Very excited to share initial results from our adaptive DBS for OCD trial in
@NatureMedicine
. 5/5 responders and ventral striatum ephys signals that may be promising for closed loop control. Brava, 1st au
@NicoleProvenza
! Great team
@BrownBME
Borton,
@bcm_ocd
Goodman, Storch.
1/4 Check out our new article in
@eLife
. We discovered rhythmic patterns within the human insula that form gradients and traveling waves across the cortical surface.
@neurojosh
@ChenWuMD
@KBijanki
New paper out in
@JNNP_BMJ
on our systematic review and meta-analysis demonstrating the safety and efficacy of
#DBS
for treatment-resistant
#OCD
. Great work by co-first authors
@ron_gdt
and
@RicardoANajera
Every opportunity to highlight clinical research efforts to US Congress is critical. We recently did so for
#DBS
for
#OCD
in this panel discussion featuring one of our patients and postdoc
@NicoleProvenza
.
I’m greatly honored and excited to serve. Thanks to Walter Koroshetz
@NINDSdirector
for the nomination. Look forward to working with him and BRAIN Initiative director John Ngai and the Councils.
Proud to have
@SameerShethMD
as a colleague at
@BCMNeurosurgery
Sameer was just appointed to two NIH advisory councils. One for the BRAIN initiative and one for NINDS.
Great Conjunction of Jupiter and Saturn, captured on my Dad’s amateur telescope. Enlarge and you can see the rings. 400 years since the two were this close together in the sky.
1/7 Check out our recent paper in
@brainstimj
drilling down on prefrontal connectivity using a unique opp from our
#BRAINInitative
funded
#DBS
for
#Depression
trial. We have DBS leads in VC/VS and SCC, and sEEG throughout PFC.
Soaking up amazing science and enjoying global friendships at 2nd DBS Experts Summit in Wurzburg hosted by the inimitable
@volkmann_jens
.
@foxmdphd
@HMayberg
We're back to canceling elective surgeries. The selfishness and misinformation-fed ignorance behind refusal to
#vaccinate
and
#MaskUp
is filling up hospitals and preventing needed care. A terrible, avoidable tragedy.
@StLukesHealthMD
@BCMNeurosurgery
The NINDS K12 award was critical in my early career. Highly encourage neurosurgeon-scientists to apply in first year of faculty job. Tune in for info from NINDS's Stephen Korn and my residency mentor Emad Eskandar.
@nsurgchick
@CNS_Update
@NINDSdirector
Day 1 of kids’ spring break well-spent delivering 120 lunches to kids in Houston’s Fifth Ward via fantastic organization
@KidsMealsInc
. Teaching our kids to
#GiveBack
.
Awesome all-woman early career mini-symp at
#SfN2023
starting now!! MIN04: Advances in DBS: From Mechanisms to Applications organized by
@Steph_SPisto
&
@scernera1
. Very proud my postdoc
@NicoleProvenza
will be presenting her work on intracranial neural biomarkers of OCD.
Human intracranial neuroscience research provides truly unique opps to study brain function with an 👁️ towards treating debilitating neuropsych disorders. As we learn, we must maintain the highest ethical standards, as we discuss here 👇🏼
@NeuroCellPress
Got the NOA for the R01. Thanks to
@NINDSfunding
for supporting research to ensure all
#stroke
patients have access to high quality screening for treatment. And for those applying for funding - don’t give up. This took many (read: MANY) attempts...
"It was suddenly like I was back online." Amazing language patients use to describe their experience with DBS for depression. Here's an article about our sEEG-informed depression DBS trial from POV of our first subject.
@drpouratian
@KBijanki
We were honored to host Dr. Julie Pilitsis as our Annual Gildenberg Lecturer this morning. Julie is an amazing clinician researcher and a great friend. And is now about to be just the third neurosurgeon medical school dean! Brava!
This morning we hosted the 14th Annual Gildenberg Lectureship with invited lecturer Dr. Julie Pilitsis of
@AMCNeurosurgery
who's lecture was titled "Can focused ultrasound change the pain game?"
We are honored to have had her speak with our residents and visit Houston!
I’m thrilled to announce that this week I started as a tenure track assistant professor and
@McNairFdn
Scholar in
@BCMNeurosurgery
with an adjunct appointment in
@RiceECE
! (1/3)
Extremely proud of
@BCMNeurosurgery
PGY5 resident Nisha Giridharan
@ngiridh
for winning the
#TANS2023
Resident Research Award for her NIH
#R25
funded work on DBS for OCD in my lab this year. Functional/epilepsy programs out there: watch for this rising 💫💫!!
What a fantastic treat to spend time with
@BShofty
@rshervin
@50kDinar
@IM_Inman
at
@UofUNeurosurg
. Ben and Shervin are the future of functional neurosurgery! Amazing program, wonderful hosts. I even got drafted to play ball in case this neurosurgery thing doesn’t work out…
Our new paper is out now in
@brainstimj
. Here we report surgical considerations for our hybrid sEEG-DBS intracranial monitoring approach to treat network-level dysfunction in treatment resistant depression.
Meet the new robot in town – our ROSA at
@VAHouston
. Her maiden voyage was also the first robotic sEEG case in the VA system. Excited to leverage this technology to help our vets.
#Neurosurgery
#NeuroTwitter
1/4 In our new
@ScienceAdvances
article, we used
#Neurogrid
, a thin-film, non-penetrating, high-channel count neural interface, to record human single neuron spiking activity:
Our new paper in
@theJNS
compared awake vs. asleep
#DBS
for
#Parkinson
's across several dimensions in 122 patients. Motor improvement, L-dopa reduction, and TEED did not differ, and asleep procedures were significantly faster. (1/4)
1/5 In our new
@SfNJournals
#JNeurosci
article, we used a multiscale approach to measure the spatial reach of neuronal coherence and spike-field coupling during cognitive tasks in humans.
So proud of my co-resident and neurosurgical brother
@BrianNahed
, the new Joanne & Anthony Migliaro Endowed Scholar at
@MGHNeurosurg
. Bri, love u, man!
Tremendous honor to give Grand Rounds
@NeurosurgUCSF
this morning. Thanks to
@ManishKAghi
and
@ChangLabUcsf
for the invitation. Your department is a model of the bright future of neurosurgery. Looking forward to talking with your residents this afternoon.
Great talk
@NeurosurgUCSF
grand rounds this morning on precision neurosurgery for treatment resistant psychiatric disorders by
@BCMNeurosurgery
superstar and my good friend
@SameerShethMD
. Sameer joined us despite the terrible weather and lack of electricity in Houston!
@HMayberg
holding court after keynote, mentoring the next gen of leaders in a manner befitting the Women in Neuromodulation theme of DBS Think Tank X
@DBSThinkTank
The Sheth Lab is looking for a motivated Engineer/Programmer to support our expanding EMU-based research efforts on human neuroscience and meuromodulation. See posting here: Please RT!
@BCMNeurosurgery
Challenging secondary dystonia, targeted both STN and GPi bilaterally to hedge our bets, but with just one pair of burr holes and one IPG. Increased therapeutic potential with minimal cosmetic "cost" to pt.
@StLukesHealthTX
@StLukesHealthMD
@BCMNeurosurgery
@BShofty
First in Texas! Dual DBS for complex movement disorder with 4 leads into the new Vercise Genus R32 channel generator. Patient leaves happy with only 1 chest incision!
@BCMNeurosurgery
#functional
fellowship, breaking boundaries under
@SameerShethMD
with the help of Dr. Sharma.
Check out our other paper in
@brainstimj
on interactive holographic stereotactic planning for sEEG and DBS electrode placements. This method integrates patient-specific brain models into a group-based 3D virtual reality environment.
Excited to put out this new content for our rapidly growing field of stereotactic and functional
#neurosurgery
. Congratulations to my co-editor
@drpouratian
of
@UCLAHealth
and thanks to the chapter authors, all leaders in this field!
@Nature
piece re
@neuralink
's first human implant. Will advertised, cherry-picked sound bites become the new normal means for comms? On other hand, I hope increased awareness ➡️ increased interest in these promising neurotech therapies.
@motifneuro
Proud of this rising 💫 functional neurosurgeon, whom I first met when I was a resident
@MGHNeurosurg
and he was
@harvardmed
med student. Way to go, Jimmy! Congratulations on the recruitment,
@RussellLonser
!
Congratulations to Dr. Jimmy Yang! He was awarded a NINDS (
@NIH
) K12 grant (
@NRCDP_K12
) for his research into anterior thalamic stimulation for medically-refractory epilepsy. This grant will propel this critical science and his work.
@NeurosurgeryOSU
#neurosurgery
Happy to announce I'm moving the lab to the Dept of Neurosurgery at Baylor College of Medicine. Very excited to collaborate with so many fantastic neuroscientists!!
@BCMNeurosurgery
@bcmhouston
@SameerShethMD
Researchers captured over 1K hours of brain recordings from patients w/ OCD to improve the design of deep brain stimulation treatments for neuropsychiatric disorders. Read more:
#NIH
@USBrainAlliance
@NINDSNews
Thrilled to share the score for my NIH R01 on novel approaches to image-guided intratumoral delivery of immunotherapies. I’m eternally grateful to my mentors and collaborators who helped make this a reality!
@PatrickHwuMD
@ANaingMD
Feeling very inspired this week and fortunate to be guided by incredible mentors such as
@lola_chambless
who became an endowed chair and
@SameerShethMD
who honored us with a visiting professor visit and grand rounds talk
@VUMC_Neurosurg
! Mentors really light up the path 🤩
Check out the new proceedings of last year’s DBS Think Tank highlighting cutting-edge neuromodulation, adaptive stimulation, AI, computational modeling and more!
The Deep Brain Stimulation (DBS) Think Tank XI proceedings is published! “Pushing the Forefront of Neuromodulation,” the updates, paper and meeting were highlighted by
@ndosenbach
who presented research recently published in
@Nature
w/Evan Gordon to identify and characterize the
1/5 New preprint from our DBS for depression trial in partnership with
@bostonsci
. We share a novel inverse programming algorithm, DBS Illumina 3D, to assist with clinical programming of DBS stimulation parameters using patient-specific imaging.
Attend our DBS for OCD CME workshop 10/14/22 to learn/discuss surgical targeting and DBS programming. Free for trainees. In-person or virtual. Register: . Practical, case-based approach to demystify and increase accessibility to DBS for OCD. 👉🏼Pls RT!
What an honor and pleasure to bring
@DanielYoshor
back to his
@BCMNeurosurgery
roots for the 10th Sawaya Lecture. Inspiring talk on leadership and generosity honoring his mentor Dr. Sawaya. Dinner with 6 neurosurgery chairs was momentous!!
It was a real honor to host
@DanielYoshor
from
@PennNSG
for the tenth annual Raymond Sawaya lecture
@BCMNeurosurgery
. They each have left a remarkable legacy and I am grateful to both of them for their positive impact on my career.
And that’s a wrap on
@ASSFNeurosurg
meeting! Capping it off with receiving the best clinical poster award (!) and some quality time with two of my favorite people
@SameerShethMD
@NicoleProvenza
. This engineer is 100% sold on neurosurgery meetings being the most fun 🤓
Great addition to the literature on DBS for OCD. Evidence in favor of the efficacy of this critical therapy is growing fast. Now we have to work on more consistent insurance coverage and increasing patient referrals to experienced programs.
@bcm_ocd
Last month,
#BCMNeurosurgery
welcomed Drs. Benjamin Hayden and Sarah Heilbronner to the team as McNair Scholars!
Learn more about their areas of focus → 🧠🔬
Grateful beyond words to
@theNCI
for funding my research and converting my R01 to an R37 MERIT award. Our lab
@MDAndersonNews
is ready to go! Thanks as well to my tremendous mentors who helped make this dream come true
@PatrickHwuMD
@ANaingMD
Extremely proud of Anusha, now Dr. Allawala!! Anusha gave an oratorical masterpiece of a defense at
@Brown_BME
. Her efforts were critical for our DBS for depression trial and earned her a prestigious NIH F99/K00. Way to go
@neuronush
!!
@NeurosurgUCSF
is lucky to have u!
Officially DOCTOR ALLAWALA! Exceptionally grateful to
@SameerShethMD
for being a brilliant mentor and advocate for me during this process, my advisor Dave Borton, and to my committee for their thoughtful feedback.
Next stop:
@NeurosurgUCSF
!
DBS for OCD has been approved by FDA HDE since 2009, but is highly underutilized. With outcomes as good as they are, we need to increase awareness of this life-improving therapy.
Series of webinars on DBS sponsored by the Int'l Neuromodulation Soc featuring international speakers starts tomorrow morning U.S. time. Register at . Thanks to Paresh Doshi
@PKD2012
in Mumbai for organizing.
Super excited for and proud of
@KBijanki
for getting her R01! Nailed it on her first try! (much more than I can say for my first…) Great project taking advantage of intracranial opps in epilepsy and TRD patients.
@BCMNeurosurgery
@bcm_neurosci
@NINDSdirector
My R01 was funded today! Looking forward to studying intracranial mechanisms of mood with
@SameerShethMD
,
@drpouratian
, Wayne Goodman, Cameron McIntyre, Sanjay Mathew,
@SuthanaLab
, David Borton, Jeff Cohn, and Meghan Robinson!