Sherif El-Khamisy
@SEK2016T
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A pharmacist fascinated by how cells maintain genome integrity in health and disease. Love running, tennis and squash
Joined July 2016
Excellent meeting at Westminster with the U.K. Minister for Science, Research and Innovation, George Freeman MP: Open Science, Research Security, mental health and the levelling up agenda were the highlights.
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Breast cancer relapse is driven by dormant cells that hide for years before reawakening. Our new review decodes how these cells survive—and how we can target them to stop recurrence for good. 👉 Read here:
nature.com
Oncogene - Decoding the adaptive survival mechanisms of breast cancer dormancy
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🧬 New from the lab - we’ve uncovered how a key protein, NuMA, helps repair damaged DNA and protect important control regions of our genome, especially after oxidative stress—protecting the genome = protecting health. Read more:
cell.com
Abugable et al. investigated the role of ADP-ribosylation in NuMA function during DNA repair. They demonstrate that ADP-ribosylation-deficient NuMA impairs repair kinetics and transcription and fails...
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Unprecedented challenges in UK Higher Education 🎓 Redefine the future of workforce sustainability and research excellence. Join the conversation and share your ideas: https://t.co/yi1b3Sh7Zl
#ResearchUK #HigherEducation #InnovateTogether
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Read our latest: Nucleoside supplementation rescues all phenotypes associated with PARG inhibitor sensitivity. From @Prof_S_Taylorl lab, Manchester Cancer Research Centre @MCRCnews.
academic.oup.com
Abstract. A subset of cancer cells are intrinsically sensitive to inhibitors targeting PARG, the poly(ADP-ribose) glycohydrolase that degrades PAR chains.
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The economic model of funding the UK HE ecosystem is broken https://t.co/AON8UECIwh
qmucu.org
a live page of all the redundancies and restructures happening across UK Higher Education. Page is updated regularly.
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Not only the Science is TOP at the #EMBOdnaDamage in #Lonavala but venue is an oasis and food is incredible !!! And one person made it all possible... Thank you @Arnab_RC1 🙏🙏🙏
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Senataxin modulates resistance to cisplatin through an R-loop mediated mechanism in HPV-associated Head and Neck Squamous Cell Carcinoma https://t.co/K1v8ZZRbsR
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I am very proud of our paper on micronucleus formation published today in @Nature with @David_J_Adams and our collaborators!!! @Cambridge_Uni @UKDRI @sangerinstitute @TINS
https://t.co/4sBtfc5rrq
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Genomic mapping of single-strand breaks is crucial to understanding links to human diseases and gene transcription. Stay up-to-date with the latest developments in this field: https://t.co/aCfobXd4PL
#GenomicMapping #SingleStrandBreaks #HumanDiseases #GeneTranscription
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Fantastic opportunity here - don't miss it!
We have launched a major cancer research recruitment campaign, in partnership with @SheffieldHosp & with dedicated funding from @yorkshirecancer. Find out more & apply by 18 Jan 👉 https://t.co/9Hrp543bZ0
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Strange things are happening down at the University..... come along and join us for Discovery Night Part 2 #biofest The University of Sheffield 15th November, Firth Court, from 4pm onwards. https://t.co/zfio1FmCrg
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If you are interested in making a difference in cell replacement therapies, don't miss this opportunity for a fully funded MRC DiMeN PhD: https://t.co/ohTesd4KuW
findaphd.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Enabling safe and efficient generation of stem cell-based therapies at University of Sheffield, listed on FindAPhD.com
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Pleased to share that work from my @UniofBradford STARTER Fellowship is now published @iScience_CP. We demonstrate the unique glycosylation of tumour-expressed CD13, which impact its detections and tumour-specific functions. @ICT_Bradford @UoBPaMS
https://t.co/2VKX4QBVuV
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@professor_dave I am sorry to hear this Dave. I am not surprised as this is one manifestation of the recent hypocrisy and double standard revealed to us all. I cannot believe we are in UK and 20th century.
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A 90ft long E.Coli has been suspended from the ceiling of #Sheffield Winter Garden (once again)! 5 million times larger than the actual bacteria, the inflatable sculpture by artist @lukejerram, has been installed for @sheffielduni’s BioFest. 🦠🎨 https://t.co/JWYYoSqG60
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Are you skilled in stem cell disease modelling or genomics and computational biology? Check out this MRC-funded post: https://t.co/Wq4gIuvhrq For more information, check out this article
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Congratulations to Dr Hannah Crane for passing her PhD VIVA yesterday. Thanks to examiners: Grant Stewart (Birmingham) and Dan Lambert (Sheffield).
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