Ruben QC
@RubenQC_Lab
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Interested in dynamics in life and biomedicine, with a focus on mitochondria
Joined April 2019
🔬Honored for the opportunity to contribute this viewpoint @NatMetabolism where we discuss on Mitochondrial Transfer; its evidences, challenges and opportunities, with plenty of room for exciting research yet to come! https://t.co/c82878ivub
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Now online! Protein restriction reprograms the multi-organ proteomic landscape of mouse aging
cell.com
Comprehensive proteomic analysis of 41 mouse tissues reveals tissue-specific aging hallmarks and demonstrates that dietary protein restriction mitigates age-related molecular changes, improves...
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Ya están abiertas las inscripciones para apuntarte a las actividades de la Semana de la Ciencia y la Tecnología en el CSIC, ¡no te lo pierdas!
👩🔬Del 3 al 16 de noviembre, celebramos la Semana de la Ciencia y la Tecnología en el @CSIC ¿Quieres participar en las actividades? 📢Próximo lunes, 20 de octubre, se abren las inscripciones➡️ https://t.co/WkhTaFLbpB
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The brain did not evolve to think, but to regulate the energetic state of the organism. https://t.co/cAijs8Hqfi
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A new blood test to aid with the diagnosis of Alzheimer’s disease has been approved by the US FDA https://t.co/VHPPNa9qej
nature.com
Nature - A second blood test has been been approved by the US Food and Drug Administration to assist in diagnosing Alzheimer’s disease. Will these tests change how cognitive decline is measured?
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#Throwback PERSPECTIVE | H Ren, Y Tang & D Zhang The emerging role of protein l-lactylation in metabolic regulation and cell signalling https://t.co/vGYVQxWRRd
nature.com
Nature Metabolism - In this Perspective, the functions of the recently identified post-translational-modification protein l-lactylation in the regulation of cellular metabolism and signalling are...
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Now online! Choreography of rapid actin filament disassembly by coronin, cofilin, and AIP1
cell.com
The rapid turnover of actin filament networks drives eukaryotic cell migration and morphogenesis. Single-particle cryo-EM structures reveal how the conserved actin-binding proteins coronin, cofilin,...
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⚠️⏰ Last days! Don't miss this opportunity!
¡Últimos días para inscribirse al CajalXmas Meeting! Recordad que gracias a @SENC_ , este año contamos con financiación a socios estudiantes SENC que vengan de fuera de Madrid, así que si conocéis a colegas interesados, ¡animadles a participar! 😊
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⏰⚠️ Run! Don't miss this opportunity!
¡Últimos días para inscribirse al CajalXmas Meeting! Recordad que gracias a @SENC_ , este año contamos con financiación a socios estudiantes SENC que vengan de fuera de Madrid, así que si conocéis a colegas interesados, ¡animadles a participar! 😊
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In the latest issue! Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures
cell.com
A 50-year multi-tissue proteomic atlas reveals transcriptome-proteome decoupling, proteostasis decline with amyloid accumulation, and asynchronous aging clocks, identifying circulating senoproteins...
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The October issue of Science #Immunology is out! This month's cover highlights a Review that delves into #brain #tumor development and examines factors contributing to the immunosuppressive brain tumor microenvironment. Learn about this and more: https://t.co/wXyU8bE7vb
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The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases
nature.com
Nature Metabolism - The authors introduce the Neurolipid Atlas, a dynamic resource for the community to gain insight into lipid alterations in neurodegenerative disease, and they leverage the...
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Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations @ShanRhoads and team! 🎉 https://t.co/BPxKlbU6Ou
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#Throwback REVIEW | Sarah-Maria Fendt et al Metabolic heterogeneity in cancer https://t.co/wCnxCM6Cco
nature.com
Nature Metabolism - Demicco, Liu et al. discuss how metabolic adaptations in cancer contribute to tumour progression. These adaptations entail high spatial and temporal metabolic heterogeneity,...
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Following malignant transformation, small cell lung cancer cells hijack neuronal synaptic signaling to promote tumor growth @Nature
@Stanford @BrighamWomens @humsav @michelle_monje 🇺🇸 https://t.co/TvnZoHdthc
@UniCologne 🇩🇪 https://t.co/vLV3feSlQG
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E. coli engineered to display cytokines destroy hard-to-treat tumors by boosting the activity of local native and adoptive immune effector cells #NBTNV
https://t.co/hdarcfpPlO
https://t.co/dBvpLmK7SF
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🚨PhD position available! Join our new lab @CNC_CSIC to explore the intersection of neural development and cancer. Start: Spring 2026. 🧠🧬 📩Apply now! #PhD #DevelopmentalNeuroscience #CancerNeuroscience
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And best short talk at #senc2025!!! Congrats Andrea @ValinoAndrea!!! So well deserved and so so happy for you!👏🥂
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Dynamic fibroblast–immune interactions shape recovery after brain injury | Nature
nature.com
Nature - Spatial transcriptomic studies and lineage tracing reveal that, after brain injury, transient profibrotic fibroblasts develop from existing brain fibroblasts, infiltrate lesions, regulate...
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Regi Mengual kicking it at the #SENC2025 podium with her talk on mitochondrial transfer in the nervous sytem! #proudPI @SENC_ @InstitutoCajal
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