Hai-Bin Ruan 阮海斌
@RuanLab
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The Ruan Lab at U of MN is driven to understand Metabolic Physiology.
Minneapolis, MN
Joined February 2019
We are accepting applications for fall 2026 for the PhD graduate program in Physiology. Come and join an amazing group of students and faculty! https://t.co/FHjlT81Vm8
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Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @Cell_Metabolism @RockefellerUniv
cell.com
Khan et al. apply machine learning to identify substrates of UNC93A, SLC45A4, and SLC25A45. Biochemical assays and in vivo metabolite tracing establish SLC25A45 as a key mediator of mitochondrial...
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The latest from our lab in the cover of @CircRes: Macrophage-derived CCL24 exacerbates fibrosis and impairs cardiac function via CCR3. Work led by Preethy Parthiban in collaboration with Jop van Berlo's lab. Open access: https://t.co/tPelmwVeWv
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Please join us for tomorrow's IBP seminar series as we welcome Dr. McCole @DecMcCole. “Regulation of Intestinal Epithelial-Macrophage Barrier Properties by the Inflammatory Bowel Disease Risk Gene, PTPN2”
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In the latest issue! Quantifying the varying harvest of fermentation products from the human gut microbiota
cell.com
Fermentation products are the most abundant gut microbial metabolites absorbed by the host, with important dose-dependent consequences for health. In this study, we present a systems-level analysis...
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As Vice Chair, I am delighted to invite you to join us for our GRC Bones and Teeth, taking place January 25–30, 2026, at the historic Hotel Galvez in Galveston, TX, a cherished venue. We look forward to welcoming you to what is sure to be an exciting and memorable meeting!
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1/11 In @ScienceMagazine: A new perspective on how our intestines renew. Cells are not “pushed out” by crowding or die from apoptosis. Instead, cells play a mechanical tug-of-war, where weaker cells extrude, reframing gut renewal as force-regulated.
science.org
Cell extrusion is essential for homeostatic self-renewal of the intestinal epithelium. Extrusion is thought to be triggered by crowding-induced compression of cells at the intestinal villus tip. In...
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We are proud to be a founding contributor to https://t.co/pzRYWSMmaI, a repository developed by @TheTafesseLab & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: https://t.co/OdFWCOYmtu
#lipidtime
arxiv.org
Lipid-protein interactions play essential roles in cellular signaling and membrane dynamics, yet their systematic characterization has long been hindered by the inherent biochemical properties of...
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The Verkerke lab is hiring at all levels. We apply metabolic and bioenergetic techniques to investigate how pathways are rewired in pathophysiology. Experience in bioenergetics,cancer metabolism, metabolomics, molecular biology is a bonus. Email averkerk@umn.edu to apply!
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Online now: Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity
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The wait is over, it’s back! 🧪 Granulocyte Meeting 2025 | 15–18 Sept | Shanghai. Big science. Big names. Big City. Don’t miss it. 🔗 https://t.co/f6TmBaKLjc
#Gmeeting2025 #Granulocytes #ThePowerOfMany
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Understanding the predictors of metabolic dysfunction-associated steatotic liver disease— Peter Crawford @ketonemics & team @umnmedschool suggest ketogenesis serves a protective role in MASLD-MASH progression via processes other than fat oxidation. https://t.co/Dl444xqzgH
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We’re thrilled to welcome Dr. Carla Rothlin(@carlarothlin) as our new Director of the Center for Immunology and Dr. Sourav Ghosh as CFI Program director, Immunology of Tissue Resolution, Repair, & Regeneration at UMN! Both join us from Yale and officially start in August 2025.
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The first graduates from our new Physiology Master's program. We are very proud!
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New! Online now: Protein O-GlcNAcylation and hexokinase mitochondrial dissociation drive heart failure with preserved ejection fraction https://t.co/nyWG12edzY
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🗓️ Save the Date!🗓️Join us for the 2025 Blumenthal Memorial Lectureship Series featuring Jenny Ting, Ph.D. on April 25, 2025, from 12:00 PM - 1:00 PM at 2-620 Moos Tower. Don’t miss this exciting talk! To save to your calendar: https://t.co/lnHMzM0A80
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As we gear up for @APSPhysiology Summit, our subcommittee created a Spring Newsletter with helpful tips, mentoring opportunities, & fun things to do in Baltimore. Be sure to check it out! https://t.co/G6DLJ3EeKF
#wearephysiology #gitwitter @ajpgi
canva.com
Check out this US Letter designed by Kristen Engevik.
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This is the most important paper in the circadian field in over a decade. A completely new clock component that is evolutionarily conserved. @Eric_E_Zhang @susanksgolden @ @SRBR_Outreach
https://t.co/Gh8fUhDeP7
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Attending #APSSummit25 & looking to expand your #gil_trainee network? Sign up to participate in our Mentoring on the Go! program - whether you're a trainee, ECR or established PI, all are welcome to help foster the amazing community of GI&Liver researchers!
Are you planning out your #APSSummit2025 yet? We're excited to organize Mentoring on the Go! where we match up GIL trainees with experts in the field to meet during @APSPhysiology Summit in April. Sign up! Trainee: https://t.co/1bMutTs34w Mentor: https://t.co/QdydmSuhl2
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#Adiposetissue.org: New Knowledge Portal Enhances Obesity and Metabolism Research The new platform https://t.co/LdN2U4Knkd, developed by #HelmholtzMunich, Karolinska Institutet, and Steno Diabetes Center Copenhagen, centralizes molecular and clinical data from 6,000+
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