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Fikadu G. Tafesse Profile
Fikadu G. Tafesse

@TheTafesseLab

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Infectious diseases I Bacteria I Viruses I Lipidomics I Sphingolipids I Nanobodies I Alumnus: @UtrechtUni @whiteheadinst/MIT @ragoninstitute of MGH, MIT&Harvard

Portland, OR
Joined March 2016
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@TheTafesseLab
Fikadu G. Tafesse
4 months
Have you published lipid-protein interactome data? Please let us know, we’d love to include it in the repository. The goal is to build a centralized hub for the scientific community. Thanks to Gaelen Guzman, a graduate student/postdoc in the lab who built it from scratch.
@basktastic
Jeremy Baskin
5 months
We are proud to be a founding contributor to https://t.co/pzRYWSMmaI, a repository developed by @TheTafesseLab & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: https://t.co/OdFWCOYmtu #lipidtime
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@Tgondii2020
Mebratu Bitew
6 days
Thrilled to share that my new paper has been published at @NatureComms @NaturePortfolio. We conducted a genome-wide CRISPR screen in Toxoplasma gondii and identified GRA38, a dense granule protein, as a key regulator of lipid homeostasis in Toxo.
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nature.com
Nature Communications - Here, using a genome-wide CRISPR screen, Bitew et al. identify GRA38, a phosphatidic acid phosphatase, as a key factor in Toxoplasma gondii adaptation to lipid-rich...
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@MekdesDaba
Mekdes Daba
19 days
የማርበርግ ቫይረስ በሽታ ዕለታዊ ሁኔታ ህዳር 25/ 2018 Marburg Virus Disease Daily update, Ethiopia December 04/ 2025 @FMoHealth @EPHIEthiopia
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@MekdesDaba
Mekdes Daba
30 days
የማርበርግ ቫይረስ በሽታ ዕለታዊ ሁኔታ ህዳር 14/ 2018 Marburg Virus Disease Daily update Ethiopia November 23/ 2025 @FMoHealth @EPHIEthiopia
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@Gio_Dangel0
Giovanni D'Angelo
2 months
Our Single cell and Spatial Metabolomics Online day is back for its 2nd edition! After the success of the 2024 edition, December 10th is meant to become a metabolomics tradition.
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@TheTafesseLab
Fikadu G. Tafesse
4 months
Have you published lipid-protein interactome data? Please let us know, we’d love to include it in the repository. The goal is to build a centralized hub for the scientific community. Thanks to Gaelen Guzman, a graduate student/postdoc in the lab who built it from scratch.
@basktastic
Jeremy Baskin
5 months
We are proud to be a founding contributor to https://t.co/pzRYWSMmaI, a repository developed by @TheTafesseLab & Schultz lab to increase accessibility to proteomics data from multi-functionalized lipid analogs! Check out the website & preprint: https://t.co/OdFWCOYmtu #lipidtime
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@JAMA_current
JAMA
3 months
A study published in JAMA found acetaminophen use during pregnancy was not associated with children’s risk of autism, ADHD, or intellectual disability. JAMA Deputy Editor Linda Brubaker, MD, MS, spoke with senior author Brian Lee, PhD, about the study’s findings and its
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@ASBMB
ASBMB
4 months
The Jan. cover of @jlipidres depicts a key step in #lipid metabolism, and features research from the paper "Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids." https://t.co/5XZkGrWUOm. #lipidomics
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@basktastic
Jeremy Baskin
4 months
Faculty opening in @CornellChem at the Assistant Professor level in the area of chemical biology, broadly defined! https://t.co/6X85aEPXv6 #chemjobs
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@TheTafesseLab
Fikadu G. Tafesse
4 months
Congratulations Jay @JayXiaojunTan and the team! Very important work showing critical roles for lipids in lysosomal repair pathways. #lipidtime
@JayXiaojunTan
Jay Tan
4 months
Lysosomal vacuolation has been observed for decades in many diseases. Today in @ScienceMagazine, we report LYVAC/PDZD8-mediated directional, ER-to-lysosome lipid transfer as an essential mechanism for lysosomal vacuolation. https://t.co/yrklDE9plq
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@TheTafesseLab
Fikadu G. Tafesse
6 months
Promoted to Full Professor with tenure! This wouldn’t have been possible without the incredible trainees, past & present, who made the science & the journey meaningful. Grateful to my mentors, colleagues, & collaborators. Excited for what’s next- here to the future! 🙌
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@TheTafesseLab
Fikadu G. Tafesse
6 months
Congratulations to Tim Bates from my lab, Corinna Kulicke from the David Lewinsohn lab, and all the collaborators involved, especially the John Burke lab. @OHSUNews
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@TheTafesseLab
Fikadu G. Tafesse
6 months
Excited to share our new preprint 🥳. We developed a high-affinity nanobody that binds MR1 & blocks MR1-restricted T cell activation, a powerful tool to dissect MR1 biology in infection, inflammation & cancer. https://t.co/cgOqNzdUgO
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@TheTafesseLab
Fikadu G. Tafesse
7 months
It’s finally out! Started this project as a PhD student in the Joost Holthuis’s lab & now it’s finished by my PhD student. Full-circle moment and the end of an era. 😊 Huge thanks to Gaelen and everyone who made this happen. @OHSUNews @PNNLab #lipid https://t.co/oAwQdwNQly
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pubmed.ncbi.nlm.nih.gov
Sphingomyelin (SM) is a major component of mammalian cell membranes and is particularly abundant in the myelin sheath that surrounds nerve fibers. Its production is catalyzed by SM synthases, SMS1...
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@TheTafesseLab
Fikadu G. Tafesse
7 months
Congrats to lab alumni Scotland Farley for leading this work, and our long standing collaborators at @PNNLab. @SchultzLabOHSU
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@TheTafesseLab
Fikadu G. Tafesse
7 months
Excited to share our latest preprint! Using integrated global lipidomics and proteomics, we show that SARS-CoV-2 variants induce conserved changes in host lipid metabolism pathways. @OHSUNews @PNNLab https://t.co/Q5mGQV0meh
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biorxiv.org
The rapid evolution of SARS-CoV-2 has led to the emergence of numerous variants with enhanced transmissibility and immune evasion. Despite widespread vaccination, infections persist, and the mechan...
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@MolCellBiophys
Liana C Silva Lab
7 months
What a fantastic 3rd FEBS Special Meeting on Sphingolipid Biology. It was an absolute pleasure to host such an inspiring gathering of researchers, collaborators & friends in the lipid community Thank you to all speakers, attendees & sponsors for making this possible! @SL_Biology
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@TheTafesseLab
Fikadu G. Tafesse
7 months
Have you ever wondered how repeated vaccination shapes our immune responses, and whether timing between doses matters? Check out our latest work! https://t.co/bs6WbELMFJ
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nature.com
Communications Medicine - Wrynla et al. assess humoral immunity elicited by the monovalent XBB.1.5 COVID-19 vaccine in participants who did or did not previously receive the bivalent...
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@TheTafesseLab
Fikadu G. Tafesse
10 months
I had an amazing time visiting Uni Victoria @uvic @UVicBCMB. It was wonderful meeting students and faculty- thank you so much, John Burke, for hosting me! #lipids and #nanobodies
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