Different COVID-19 vaccine formulations have distinct effects on the stromal cell landscape and function of draining lymph nodes @SciImmunology @SalmiLab https://t.co/OKcbBnfvad

This paper:

In our recent Sci. Signal. paper by Gutjahr et al. @GutjahrJulia 10.1126/scisignal.adt2678 we did not discuss in detail this point: "Using CXCL12 should improve the efficiency of in vitro blood production" Fortschritt in der künstlichen Blutproduktion

A team finds that the #chemokine CXCL12 can support the production of #RedBloodCells in mice, suggesting that this pathway could be investigated for the treatment of disorders related to red blood cells. @stevenduke @GutjahrJulia @QMULWHRI https://t.co/IH59m8o8nq

Un joli erythroblaste. Un érythroblaste est une cellule jeune de la lignée des globules rouges, présente dans la moelle osseuse. Elle contient encore un noyau, ce qui la distingue des globules rouges matures (érythrocytes), qui en sont dépourvus.

#FluorescenceFriday & Erythroblast Erythroblast stimulated with CXCL12, stained for CXCR4 (green) and nuclei (blue). Captured via Correlative Light & Electron Microscopy by @JemimaBurden Learn more: https://t.co/TsOpLonSF4 @GutjahrJulia @RotAntal @ScienceMagazine @scisignal

In a new study, researchers find that the chemokine CXCL12 can support the production of red blood cells in mice, suggesting that this pathway could be investigated for the treatment of disorders related to red blood cells. Learn more in @SciSignal: https://t.co/5HEMNfVX1F

In a new study, researchers find that the chemokine CXCL12 can support the production of red blood cells in mice, suggesting that this pathway could be investigated for the treatment of disorders related to red blood cells. Learn more in @SciSignal: https://t.co/5HEMNfVX1F

A team finds that the #chemokine CXCL12 can support the production of #RedBloodCells in mice, suggesting that this pathway could be investigated for the treatment of disorders related to red blood cells. @stevenduke @GutjahrJulia @QMULWHRI https://t.co/IH59m8o8nq

A preclinical study uncovers a metabolic pathway that offers a target in neuropathic pain, scientists discover how chemokines can support red blood cell production in mice, and more this week in #ScienceSignaling. https://t.co/ujJNEWxa5j

Not all chemokine signaling is about cell migration! In mouse erythroblasts, CXCL12-bound CXCR4 enters the nucleus to control gene transcription, trigger calcium bursts, and drive red blood cell formation—especially enucleation. 🔗 https://t.co/pEl4qc0BjX #chemokine #CXCR4

https://t.co/W1APRNAGlD We describe the hitherto overlooked expression of CXCR4 in erythroblasts, which do not migrate in response to CXCR4 ligation by CXCL12. Instead, CXCR4 localises to the nucleus and mediates alternative responses in erythroblast maturation and enucleation

Although chemokines are known for their role in cell migration, new work in mice shows that CXCL12 also promotes the differentiation of #erythroblasts by promoting CXCR4 signaling and activity in the nucleus. @stevenduke @GutjahrJulia @QMULWHRI https://t.co/IH59m8o8nq

CXCL12-stimulated intracellular and nuclear CXCR4 signaling mediates erythroblast enucleation to generate red blood cells @scisignal @GutjahrJulia @RotAntal https://t.co/wbx3nqu5Ro

Open access link can be found here:

Proud to share that our recent publication in Science Signaling has been featured on the Science website today! 🧬🔬 It’s a great feeling to see our work reach a broader audience. Many thanks to all collaborators Check out the feature here: https://t.co/TSnynBpRpo #Science

Dime un jugador del Real Madrid así

Poorly validated antibodies fuel the reproducibility crisis. @YCharOS1 shares a protocol for antibody validation using KO cell lines https://t.co/K1f1lGaFcq https://t.co/ufxrLxqFNB Glad that our study is cited as an example for improving data quality https://t.co/lTt6i1MTTz

🚀 New Postdoc Position 🚀 We offer a 3-year postdoc position to investigate how vascular #aging impacts #immunecell function. 🔬 We’d be grateful if you could help spread the word! 🙏 @QMUL @QMULWHRI 👉 https://t.co/LB5h3kIomR #Postdoc #AcademicTwitter #ResearchOpportunity

Only 8K? possible to screen all of these quickly, in ....decades. Would there be grant money to finance such massive katharsis?