Michael Rauh
@QMyPath
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MD/PhD; Hematopathologist/Assoc Prof, Queens U, Personalized Myeloid Cancer Pathology & Research (QMyPath) #chip #mdssm #leusm #hemepath
Kingston, Ontario, Canada
Joined May 2014
Congrats Alex McDonald on your MSc graduation @tmedQueens ! ! 🎉🍁 You made fundamental discoveries about clonal hematopoiesis and risk of Alzheimer disease, and contributions to this paper @CellStemCell . Amazing!!🤩 https://t.co/4p0kVqtQMG
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CHIP variants are often discovered incidentally in liquid biopsy testing, but is plasma cell-free DNA reliable when CHIP variants are the desired finding? 🩸@BloodAdvances @AlexBickMDPhD 🧵1/12
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Congratulations to @PMResearch_UHN's Dr. Robert Vanner, who leads a team awarded $1M through @BrainCanada and @SRC_CRS's 2025 Translational Research Grant in Brain Cancer! 🎉 🔗Learn more about the project focused on advancing #glioblastoma research:
braincanada.ca
🚨 Big news in #braincancer research! Brain Canada & @SRC_CRS are funding 2 top teams: Dr. Robert Vanner & Dr. Sheila Singh with $1M each over 3 years. @CDCR_Mac @UnityHealthTO Read more ➡️ https://t.co/o96kP7klWZ
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🚨 Big news in #braincancer research! Brain Canada & @SRC_CRS are funding 2 top teams: Dr. Robert Vanner & Dr. Sheila Singh with $1M each over 3 years. @CDCR_Mac @UnityHealthTO Read more ➡️ https://t.co/o96kP7klWZ
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Drs. Caitlyn Vlasschaert @DrFlashHeart & Michael Rauh @QMyPath (@QueensuDOM)'s study on assessing the role of clonal hematopoiesis in respiratory infection risk and vaccine responses in the elderly: https://t.co/DS7aPNA374
#NationalSeniorsDay
psifoundation.org
Grants & Awards funded by PSI Foundation
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Primary Prevention of colon cancer. We don't measure CHIP (clonal hematopoiesis of indeterminate origin, blood stem cell mutation) but it is the one factor that helps predict who will benefit from low dose aspirin https://t.co/gysOgTTkAW
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Congratulations to Alex McDonald who successfully defended her MSc thesis examination!! @QMyPath @QueensuDOM @queensgradstudy @QueensUHealth
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Check out our newly published work! We show that germline & somatic variants in DNMT3A and other CHIP-related genes are enriched in PAH, including APAH-CTD. These mutations promote inflammation and may serve as biomarkers and therapeutic targets
academic.oup.com
AbstractBackground and Aims. Multiple germline gene variants promote familial and idiopathic pulmonary arterial hypertension (PAH); however, none are consi
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🚨📢❗So proud and excited to share our latest work, "Clonal Hematopoiesis Dynamics and Evolutionary Fitness During Cancer Treatment Impact Clinical Outcomes", now available: https://t.co/EQu4Ilx2Hf🧵
medrxiv.org
Clonal hematopoiesis (CH) is the age-related expansion of mutated hematopoietic stem cells without other hematologic abnormalities. In patients with solid tumors, CH is associated with higher...
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Germline and somatic variants in DNMT3A and other clonal haematopoiesis of indeterminate potential genes contribute to pulmonary arterial hypertension | European Heart Journal | Oxford Academic! @queensutime @KingstonHSC
academic.oup.com
AbstractBackground and Aims. Multiple germline gene variants promote familial and idiopathic pulmonary arterial hypertension (PAH); however, none are consi
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We had the honor to preview @TheKingLab's new publication in @CellStemCell; 'Plot Twist: TET2 Clones Save the Brain'. If you are interested in peripheral vs. central immune cells in the brain in health and disease, check it out!
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Please check out or new paper describing a novel relationship between DNMT3A and telomeres. It truly was a team effort ! Even better when your former @Goodell_Lab baymate @TheKingLab publishes in @CellStemCell in the same issue!
Online Now! Non-canonical functions of DNMT3A in hematopoietic stem cells regulate telomerase activity and genome integrity https://t.co/Twl44S84Ps
#stemcells
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We're super excited to announce the 10 recipients of our @QueensuSCRI INAUGURAL 2025 Sinclair Graduate Scholars in Cancer Research awardees. Bravo and congratulations to Kaytlin, Marco, Simona, Samantha, Natasha, Monica, Fatin, Ashley, Laura & Julian!!!!
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“Educating the next generation expert in nephrology genetics”: we need a new workforce to deal with rapidly growing role of genetics in Nephrology! https://t.co/9h98ECHl0u
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I'm honoured to share that I've been selected as part of the final @CIHR_IRSC #VanierCanada CGS cohort! Very grateful for the support from my supervisors @QMyPath and Rob Vanner, as well as family, friends, and mentors from along the way! @QueensMDPhD @QueensuSCRI @QueensUHealth
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Congrats & thanks to Katherine King & Katie Matatall @TheKingLab for inviting us to this collaboration @CellStemCell. Also to Alex McDonald, @marcobuttigieg_ , @DrFlashHeart & Susan Crocker @QueensUHealth @tmedQueens @QueensMDPhD . Our funding from #NFRF @SSHRC_CRSH, @CIHR_IRSC
Clonal hematopoiesis (CH, blood stem cells with mutations) is considered a risk factor for cardiovascular disease and other adverse health outcomes. But today we learn about its potential benefit vs Alzheimer's disease https://t.co/mh4mToEgcD
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Collaborative work online now @CellStemCell provides insight into how mutant immune cells can help mitigate Alzheimer’s disease. Tet2-mutant myeloid cells are able to infiltrate the brain and clear β-amyloid, slowing cognitive decline.
cell.com
Matatall et al. uncover a mutation-specific association between clonal hematopoiesis (CH) and Alzheimer’s disease (AD) in mice and humans. TET2-mutant CH conferred lower odds of AD in humans and...
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Healthspan has a proteomic signature! About 3,000 plasma proteins assessed and validated in 2 cohorts. Immune response and inflammation proteins stood out. https://t.co/UZBWIhT1Ft
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