Pietro Pichierri 🇮🇹🇪🇺 @[email protected]
@PietroPichierri
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Team leader at Istituto Superiore di Sanita' working on how our cells keep their genome safe - ...to boldly go where no man has gone before... Views are my own
Rome - Italy
Joined September 2011
I just picked up a Pocket qPCR from the legendary @GaudiLabs. Can't wait to finally have some gene expression tooling. $1000 with tarrifs and tax shipped to US. https://t.co/jEXzVgq4lx
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CRISPR–Cas9 DSBs don’t just change DNA sequence — they also disrupt DNA methylation. Using @nanopore native long reads, we uncovered stable epigenetic side effects of DSB repair. https://t.co/QFzTXRQyb9
@GenomeBiology
https://t.co/rYZ9Mm5qsL
@Mengge_W @YingziZhang212 @KAUST_News
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We thank @PeterLyLab and Alessandra Brambati for the engaging discussions at today’s webinar! We wish our community a nice end-of-the-year break, and we look forward to seeing you at our first webinar of 2026 on January 13th. Explore our exciting 2026 Winter Season:
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Excellent article about the ERC-Plus fund!!
I just published: ERC-Plus: jackpot science or missed chance to fix academia? My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building. 1. First, credit where it’s due 2. But then the numbers
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10 courses for my dream bioinformatics curriculum: 1. Unix Commands with Greg Wilson https://t.co/83VHvTqbMt 2. statistics and R with Rafael Irizarry https://t.co/ofYSIiChoW
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Online Now: Attenuation of ATM signaling by ROS delays replicative senescence at physiological oxygen https://t.co/r7lXoghd6o
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Hope you all had a great Thanksgiving holiday! Dr. Arnab Chaudhuri will join us from Netherland to discuss Replication and recombination for cancer therapy. Sign up at https://t.co/XaGM9Lt62q
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What you’re seeing This figure shows how modern diets alter the gut environment, shifting microbial balance, weakening intestinal defenses, and driving low-grade inflammation linked to chronic disease. 🟡 High-fat, low-fiber diets change bile acid metabolism and reduce
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L'Istituto Superiore di Sanità si illumina di rosso questa sera, per celebrare la giornata internazionale contro la violenza sulle donne e ricordare le troppe vittime di questo crimine ingiustificabile. . #iss #istitutosuperioredisanità #stopviolenza #25novembre #noallaviolenza
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Are you a life sciences researcher interested in doing research in Germany? An EMBO Postdoctoral Fellowship could help advance your career by enabling you to pursue research in labs across Europe – including Germany – and beyond. Apply now👉 https://t.co/yDAk0vu3sn
#FundingFriday
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🐣A baby is born. Heel prick, standard newborn screen, everyone goes home. Three days later the phone rings. “Your daughter has Hurler. A nonsense mutation. Her cells stop reading the IDUA gene halfway through.” >Old world: weekly enzyme infusions, bone marrow transplant,
Today in @Nature we report a new prime editing strategy that can rescue a common cause of many genetic diseases in a disease-agnostic manner. This approach converts a redundant endogenous tRNA into an optimized suppressor tRNA, enabling a single prime edit to rescue premature
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Si è appena conclusa una delle settimane piú stressanti, che io ricordi, da quando faccio questo lavoro. Una di quelle che ti tengono sveglio la notte e assorbono ogni sinapsi disponibile. Nulla che non possa succedere a tutti, ma mi ha fatto pensare al famoso work-life balance👇
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Adding to this week reading list; this direction seems like a major unresolved puzzle.
Two fantastic stories published ~a year apart with striking confluence in findings - while age is the single most important risk factor for cancer, aging can also limit the ability of cells to undergo neoplastic transformation. https://t.co/k3A4nvttVn
https://t.co/fNiXBr14tp
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Thrilled to share our manuscript identifying C8orf33 as a novel regulator of DSB repair choice. It channels repair to NHEJ over HR by antagonizing KAT8-mediated H4K16ac. Consequently, C8orf33 loss causes excessive HR, rDNA instability and cell death. https://t.co/f9RtiqQ72n
nature.com
Cell Death & Disease - C8orf33 dictates DNA double-strand break repair choice by modulating KAT8-mediated H4K16 acetylation
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NIH grant applicants: October and November grant application submission *deadlines* will be rescheduled (🤯). Specific dates TBD. https://t.co/RWkio5joq0
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Mattarella: Va ribadito con risolutezza: la sovranità di un popolo non si esprime nel diritto di portare guerra al vicino. La volontà di avere successo di una nazione non si traduce nel produrre ingiustizia. La guerra di aggressione è un crimine
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